Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR388W
Length:
482
Number of sequences:
5887
Description:
YDR388W RVS167 SGDID:S000002796, Chr IV from 1250186-1251634, Genome Release 64-1-1, Verified ORF, "Actin-associated protein with roles in endocytosis and exocytosis; interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; recruited to bud tips by Gyl1p and Gyp5p during polarized growth; homolog of mammalian amphiphysin"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481Q3UND0    358   SKAP2_MOUSE Src kinase-associated phosphoprot...501.7     34.7     32     48GO:0005737; C:cytoplasm; IDA:MGI.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0042113; P:B cell activation; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.
482Q9NXG0    1405   CNTLN_HUMAN Centlein OS=Homo sapiens (Human)....1941.7     35     21     41GO:0005814; C:centriole; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005739; C:mitochondrion; IDA:HPA.
GO:0000155; F:two-component sensor activity; IEA:InterPro.
483Q4WUG9    288   SHO1_ASPFU High osmolarity signaling protein ...861.7     34.7     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
484B0Y3Z4    288   SHO1_ASPFC High osmolarity signaling protein ...861.7     34.7     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
485Q8TE68    723   ES8L1_HUMAN Epidermal growth factor receptor ...1171.7     35     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
486Q2H3I7    297   SHO1_CHAGB High osmolarity signaling protein ...1391.8     34.7     27     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
487B2ANF9    317   SHO1_PODAN High osmolarity signaling protein ...1231.8     34.7     31     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
488A1IGU5    675   ARH37_HUMAN Rho guanine nucleotide exchange f...4871.9     34.7     21     35GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
489Q9Y566    2161   SHAN1_HUMAN SH3 and multiple ankyrin repeat d...632     35     32     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; ISS:BHF-UCL.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:BHF-UCL.
GO:0071532; F:ankyrin repeat binding; ISS:BHF-UCL.::GO:0030160; F:GKAP/Homer scaffold activity; ISS:BHF-UCL.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
GO:0008306; P:associative learning; ISS:BHF-UCL.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0007616; P:long-term memory; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0006461; P:protein complex assembly; ISS:BHF-UCL.::GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
490Q8NFA2    376   NOXO1_HUMAN NADPH oxidase organizer 1 OS=Homo...472.1     34.3     34     57GO:0043020; C:NADPH oxidase complex; IDA:BHF-UCL.
GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016176; F:superoxide-generating NADPH oxidase activator activity; TAS:BHF-UCL.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; TAS:BHF-UCL.
491Q6TXD4    1580   DNMBP_MOUSE Dynamin-binding protein OS=Mus mu...603.6     33.9     32     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
492Q9NR46    395   SHLB2_HUMAN Endophilin-B2 OS=Homo sapiens (Hu...1202.2     34.3     27     40GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0005634; C:nucleus; IDA:HPA.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
493P43516    142   CHA6_LYMDI Chorion class A protein Ld12 OS=Ly...822.3     33.1     37     40GO:0042600; C:chorion; IEA:InterPro.
GO:0005213; F:structural constituent of chorion; IEA:InterPro.
GO:0007304; P:chorion-containing eggshell formation; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:InterPro.
494Q9U1M8    2357   MYOI_DICDI Myosin-I heavy chain OS=Dictyostel...522.6     34.7     33     56GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0005829; C:cytosol; IDA:dictyBase.::GO:0030175; C:filopodium; IDA:dictyBase.::GO:0005624; C:membrane fraction; IDA:dictyBase.::GO:0016459; C:myosin complex; ISS:dictyBase.::GO:0001891; C:phagocytic cup; IDA:dictyBase.
GO:0003779; F:actin binding; ISS:dictyBase.::GO:0030898; F:actin-dependent ATPase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0003774; F:motor activity; ISS:dictyBase.::GO:0043621; F:protein self-association; IDA:dictyBase.
GO:0030048; P:actin filament-based movement; ISS:dictyBase.::GO:0000902; P:cell morphogenesis; IMP:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0046847; P:filopodium assembly; IMP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0009847; P:spore germination; IMP:dictyBase.
495C7Z504    295   SHO1_NECH7 High osmolarity signaling protein ...1022.6     33.9     29     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
496C5DQY5    371   SHO1_ZYGRC High osmolarity signaling protein ...582.8     33.9     38     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
497Q8Y206    457   MIAB_RALSO (Dimethylallyl)adenosine tRNA meth...732.8     34.3     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006400; P:tRNA modification; IEA:InterPro.
498A6ZR73    367   SHO1_YEAS7 High osmolarity signaling protein ...322.9     33.9     47     59GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
499P40073    367   SHO1_YEAST High osmolarity signaling protein ...323     33.9     47     59GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0044459; C:plasma membrane part; IDA:SGD.
GO:0005078; F:MAP-kinase scaffold activity; IMP:SGD.::GO:0005034; F:osmosensor activity; IPI:SGD.
GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0030010; P:establishment of cell polarity; IGI:SGD.::GO:0007231; P:osmosensory signaling pathway; IPI:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.
500Q5AQ36    387   SHO1_CANAL High osmolarity signaling protein ...563     33.9     38     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0000902; P:cell morphogenesis; IMP:CGD.::GO:0034599; P:cellular response to oxidative stress; IMP:CGD.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:CGD.::GO:0090033; P:positive regulation of filamentous growth; IMP:CGD.
501C7GKW5    367   SHO1_YEAS2 High osmolarity signaling protein ...323     33.9     47     59GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
502C4YDC4    385   SHO1_CANAW High osmolarity signaling protein ...563     33.9     38     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
503E7QE10    367   SHO1_YEASZ High osmolarity signaling protein ...323.1     33.9     47     59GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
504E7LTJ6    367   SHO1_YEASV High osmolarity signaling protein ...323.1     33.9     47     59GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
505E7KMS3    367   SHO1_YEASL High osmolarity signaling protein ...323.1     33.9     47     59GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
506E7KBW4    367   SHO1_YEASA High osmolarity signaling protein ...323.1     33.9     47     59GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
507B5VHP4    367   SHO1_YEAS6 High osmolarity signaling protein ...323.1     33.9     47     59GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
508E7Q311    367   SHO1_YEASB High osmolarity signaling protein ...323.1     33.9     47     59GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
509B3LRN4    367   SHO1_YEAS1 High osmolarity signaling protein ...323.1     33.9     47     59GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
510B9W8T5    398   SHO1_CANDC High osmolarity signaling protein ...563.4     33.9     38     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
511D3Z6Q9    489   BIN2_MOUSE Bridging integrator 2 OS=Mus muscu...2423.6     33.9     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
records
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