rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | Q4V7G1 | 354 | SKAP1_RAT Src kinase-associated phosphoprotei... | 50 | 0.26 | 37.4 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042169; F:SH2 domain binding; IPI:RGD. | | | | | | | | | | | 422 | Q99MZ8 | 263 | LASP1_RAT LIM and SH3 domain protein 1 OS=Rat... | 110 | 0.26 | 37 | 31 | 45 | GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 423 | P46109 | 303 | CRKL_HUMAN Crk-like protein OS=Homo sapiens (... | 92 | 0.27 | 37 | 26 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 424 | Q5R5W0 | 261 | LASP1_PONAB LIM and SH3 domain protein 1 OS=P... | 71 | 0.29 | 37 | 37 | 51 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 425 | Q14847 | 261 | LASP1_HUMAN LIM and SH3 domain protein 1 OS=H... | 71 | 0.29 | 37 | 37 | 51 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 426 | Q751J2 | 330 | SHO1_ASHGO High osmolarity signaling protein ... | 59 | 0.3 | 37 | 39 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 427 | Q86WV1 | 359 | SKAP1_HUMAN Src kinase-associated phosphoprot... | 50 | 0.31 | 37 | 30 | 48 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003823; F:antigen binding; IPI:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; IC:UniProtKB. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB. | 428 | P30204 | 458 | MSRE_MOUSE Macrophage scavenger receptor type... | 149 | 0.31 | 37.4 | 23 | 43 | GO:0005581; C:collagen; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0034362; C:low-density lipoprotein particle; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030169; F:low-density lipoprotein particle binding; IMP:BHF-UCL.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | GO:0030301; P:cholesterol transport; IMP:BHF-UCL.::GO:0042953; P:lipoprotein transport; IMP:MGI.::GO:0034381; P:plasma lipoprotein particle clearance; IMP:BHF-UCL.::GO:0010886; P:positive regulation of cholesterol storage; IMP:BHF-UCL.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IGI:BHF-UCL. | 429 | Q5ZIR1 | 366 | SHLB1_CHICK Endophilin-B1 OS=Gallus gallus (C... | 81 | 0.32 | 37 | 27 | 44 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 430 | A7E3N2 | 527 | NCF2_RAT Neutrophil cytosol factor 2 OS=Rattu... | 53 | 0.32 | 37.4 | 34 | 51 | GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0032870; P:cellular response to hormone stimulus; IDA:RGD.::GO:0045777; P:positive regulation of blood pressure; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IDA:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD. | 431 | Q6DII7 | 345 | SKAP1_XENTR Src kinase-associated phosphoprot... | 116 | 0.32 | 37 | 23 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 432 | Q7SDM3 | 1235 | MYO1_NEUCR Myosin-1 OS=1257 / FGSC 987). GN=m... | 51 | 0.34 | 37.4 | 37 | 51 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 433 | Q5U2U2 | 303 | CRKL_RAT Crk-like protein OS=Rattus norvegicu... | 92 | 0.35 | 36.6 | 27 | 47 | | | | | | | | | | | | | | | | | | | | | | 434 | P47941 | 303 | CRKL_MOUSE Crk-like protein OS=Mus musculus (... | 92 | 0.36 | 36.6 | 27 | 47 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI. | 435 | Q5R8P5 | 365 | SHLB1_PONAB Endophilin-B1 OS=Pongo abelii (Su... | 92 | 0.37 | 37 | 25 | 38 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 436 | Q9Y371 | 365 | SHLB1_HUMAN Endophilin-B1 OS=Homo sapiens (Hu... | 92 | 0.37 | 37 | 25 | 38 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IPI:HGNC.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:HGNC.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 437 | B0CRJ3 | 1252 | MYO1_LACBS Myosin-1 OS=deceiver) (Laccaria la... | 42 | 0.38 | 37.4 | 36 | 62 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 438 | P42687 | 497 | SPK1_DUGTI Tyrosine-protein kinase SPK-1 OS=D... | 78 | 0.38 | 37 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 439 | P16277 | 499 | BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus ... | 54 | 0.39 | 37 | 35 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 440 | P20929 | 6669 | NEBU_HUMAN Nebulin OS=Homo sapiens (Human). G... | 72 | 0.42 | 37.4 | 32 | 51 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc. | | | | | | | | | | GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030832; P:regulation of actin filament length; NAS:UniProtKB.::GO:0007525; P:somatic muscle development; NAS:UniProtKB. | 441 | Q5U597 | 330 | SKA2B_XENLA Src kinase-associated phosphoprot... | 91 | 0.45 | 36.6 | 21 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 442 | Q6TGW5 | 214 | OSTF1_DANRE Osteoclast-stimulating factor 1 O... | 55 | 0.45 | 35.8 | 35 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 443 | Q6PG29 | 341 | SKAP2_DANRE Src kinase-associated phosphoprot... | 50 | 0.47 | 36.6 | 32 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 444 | O14259 | 415 | YFP2_SCHPO SH3 domain-containing protein C7D4... | 103 | 0.49 | 36.6 | 27 | 39 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:2000157; P:negative regulation of ubiquitin-specific protease activity; IMP:PomBase. | 445 | A6NI72 | 391 | NCF1B_HUMAN Putative neutrophil cytosol facto... | 97 | 0.51 | 36.6 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 446 | Q4P9K9 | 2005 | CHS8_USTMA Chitin synthase 8 OS=Ustilago mayd... | 144 | 0.53 | 37 | 30 | 41 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004100; F:chitin synthase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW. | 447 | Q55CE0 | 677 | MKCF_DICDI Probable serine/threonine-protein ... | 54 | 0.53 | 36.6 | 31 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 448 | P14598 | 390 | NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom... | 97 | 0.56 | 36.2 | 27 | 43 | GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL. | 449 | Q14185 | 1865 | DOCK1_HUMAN Dedicator of cytokinesis protein ... | 54 | 0.56 | 36.6 | 30 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007229; P:integrin-mediated signaling pathway; TAS:ProtInc.::GO:0006911; P:phagocytosis, engulfment; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 450 | Q6BVC2 | 304 | SHO1_DEBHA High osmolarity signaling protein ... | 56 | 0.56 | 36.2 | 38 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 451 | Q8BUR4 | 1865 | DOCK1_MOUSE Dedicator of cytokinesis protein ... | 54 | 0.58 | 36.6 | 30 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IDA:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. |