Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR388W
Length:
482
Number of sequences:
5887
Description:
YDR388W RVS167 SGDID:S000002796, Chr IV from 1250186-1251634, Genome Release 64-1-1, Verified ORF, "Actin-associated protein with roles in endocytosis and exocytosis; interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; recruited to bud tips by Gyl1p and Gyp5p during polarized growth; homolog of mammalian amphiphysin"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271Q9UBW5    565   BIN2_HUMAN Bridging integrator 2 OS=Homo sapi...2430.003     43.5     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
272O97902    1129   ASAP1_BOVIN Arf-GAP with SH3 domain, ANK repe...600.003     43.9     37     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
273Q8BZ71    360   STAC3_MOUSE SH3 and cysteine-rich domain-cont...510.003     43.1     35     55
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
274O43307    516   ARHG9_HUMAN Rho guanine nucleotide exchange f...660.003     43.5     27     58GO:0005829; C:cytosol; TAS:Reactome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0034220; P:ion transmembrane transport; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
275Q3UTH8    516   ARHG9_MOUSE Rho guanine nucleotide exchange f...660.004     43.5     27     58GO:0005938; C:cell cortex; TAS:MGI.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:MGI.
276Q15080    339   NCF4_HUMAN Neutrophil cytosol factor 4 OS=Hom...1020.004     43.1     30     46GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0043020; C:NADPH oxidase complex; IDA:UniProtKB.::GO:0032010; C:phagolysosome; TAS:Reactome.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006955; P:immune response; TAS:UniProtKB.::GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
277Q9DDA9    477   PACN2_XENLA Protein kinase C and casein kinas...540.004     43.5     43     56GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
278P08631    526   HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo...880.004     43.1     32     45GO:0005901; C:caveola; IDA:UniProtKB.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031234; C:extrinsic to internal side of plasma membrane; IMP:UniProtKB.::GO:0005925; C:focal adhesion; IMP:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007155; P:cell adhesion; TAS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0002758; P:innate immune response-activating signal transduction; TAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; TAS:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043299; P:leukocyte degranulation; TAS:UniProtKB.::GO:0002522; P:leukocyte migration involved in immune response; TAS:UniProtKB.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:UniProtKB.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; TAS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0050727; P:regulation of inflammatory response; TAS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; IMP:UniProtKB.::GO:0071801; P:regulation of podosome assembly; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045728; P:respiratory burst after phagocytosis; TAS:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
279Q7Z8J6    1282   MYO1_USTMA Myosin-1 OS=Ustilago maydis (strai...590.004     43.5     32     54GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
280P27870    845   VAV_MOUSE Proto-oncogene vav OS=Mus musculus ...780.004     43.5     31     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI.
GO:0006955; P:immune response; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006909; P:phagocytosis; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030217; P:T cell differentiation; TAS:MGI.
281Q4P9Q7    335   SHO1_USTMA High osmolarity signaling protein ...550.004     42.7     44     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
282Q7SIG6    958   ASAP2_MOUSE Arf-GAP with SH3 domain, ANK repe...1000.005     43.5     33     48GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
283Q96N96    652   SPT13_HUMAN Spermatogenesis-associated protei...610.005     43.1     31     54GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0046847; P:filopodium assembly; IMP:UniProtKB.::GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
284Q5DU57    656   SPT13_MOUSE Spermatogenesis-associated protei...610.005     43.1     31     54GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030175; C:filopodium; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
285P54100    843   VAV_RAT Proto-oncogene vav OS=Rattus norvegic...540.005     43.1     37     54GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0048468; P:cell development; TAS:RGD.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
286Q8VDG6    1002   M3KL4_MOUSE Mitogen-activated protein kinase ...520.005     43.1     35     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
287P13406    537   FYN_XENLA Tyrosine-protein kinase Fyn OS=Xeno...580.005     42.7     40     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
288Q9Z0W5    441   PACN1_RAT Protein kinase C and casein kinase ...890.006     42.7     33     44
GO:0007010; P:cytoskeleton organization; IDA:RGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
289P97306    403   STAC_MOUSE SH3 and cysteine-rich domain-conta...570.007     42.4     37     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0034605; P:cellular response to heat; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
290A7MBI0    444   PACN1_BOVIN Protein kinase C and casein kinas...610.007     42.4     43     56
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
291Q6ZMT1    411   STAC2_HUMAN SH3 and cysteine-rich domain-cont...910.007     42.4     33     46
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
292A0JNJ1    403   STAC_BOVIN SH3 and cysteine-rich domain-conta...570.007     42.4     37     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
293Q9NHC3    279   CED2_CAEEL Cell death abnormality protein 2 O...710.007     42     34     51GO:0005886; C:plasma membrane; NAS:WormBase.
GO:0032403; F:protein complex binding; IPI:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0043652; P:engulfment of apoptotic cell; IMP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB.
294Q9Y7Z8    1217   MYO1_SCHPO Myosin-1 OS=Schizosaccharomyces po...500.008     42.7     36     56GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0005826; C:actomyosin contractile ring; TAS:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0045121; C:membrane raft; IDA:PomBase.::GO:0045160; C:myosin I complex; TAS:PomBase.::GO:0005628; C:prospore membrane; IDA:PomBase.::GO:0030427; C:site of polarized growth; IDA:PomBase.
GO:0003779; F:actin binding; NAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; TAS:PomBase.
GO:0000147; P:actin cortical patch assembly; IGI:PomBase.::GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0045010; P:actin nucleation; IDA:PomBase.::GO:0030476; P:ascospore wall assembly; IMP:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:PomBase.::GO:0031580; P:membrane raft distribution; IMP:PomBase.::GO:0051127; P:positive regulation of actin nucleation; IMP:PomBase.::GO:0030100; P:regulation of endocytosis; IMP:PomBase.
295Q61644    441   PACN1_MOUSE Protein kinase C and casein kinas...780.008     42     38     49GO:0030137; C:COPI-coated vesicle; IDA:MGI.
GO:0008092; F:cytoskeletal protein binding; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI.::GO:0007165; P:signal transduction; TAS:MGI.
296Q9R0C8    847   VAV3_MOUSE Guanine nucleotide exchange factor...510.008     42.4     37     55GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005154; F:epidermal growth factor receptor binding; IPI:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IGI:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0030032; P:lamellipodium assembly; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IMP:MGI.::GO:0006906; P:vesicle fusion; IGI:MGI.
297P41241    450   CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus ...660.009     42     38     52GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:HGNC.
GO:0005524; F:ATP binding; TAS:HGNC.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; TAS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0050863; P:regulation of T cell activation; TAS:HGNC.
298Q08DN7    844   VAV_BOVIN Proto-oncogene vav OS=Bos taurus (B...540.009     42.4     35     54GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
299P41240    450   CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo...660.009     42     38     52GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005886; C:plasma membrane; IPI:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
300Q0VBZ0    450   CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos ...660.009     42     38     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
301Q8R1B0    408   STAC2_MOUSE SH3 and cysteine-rich domain-cont...520.01     42     40     52
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
records
Previous ‹‹ ›› Next Total records: 522 271 - 300
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::