Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR386W
Length:
632
Number of sequences:
5887
Description:
YDR386W MUS81 SGDID:S000002794, Chr IV from 1246084-1247982, Genome Release 64-1-1, Verified ORF, "Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in DNA repair, replication fork stability, and joint molecule formation/resolution during meiotic recombination; helix-hairpin-helix protein"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q04149    632   MUS81_YEAST Crossover junction endonuclease M...6320     1308     100     100GO:0048476; C:Holliday junction resolvase complex; IDA:SGD.::GO:0005634; C:nucleus; IPI:SGD.
GO:0008821; F:crossover junction endodeoxyribonuclease activity; IDA:SGD.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006281; P:DNA repair; IGI:SGD.::GO:0000712; P:resolution of meiotic recombination intermediates; IGI:SGD.
2Q6FYA6    628   MUS81_CANGA Crossover junction endonuclease M...6400     668     55     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
3Q754C9    604   MUS81_ASHGO Crossover junction endonuclease M...6308e-158     474     38     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
4Q6CPQ8    614   MUS81_KLULA Crossover junction endonuclease M...6381e-144     440     42     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
5Q6BJ48    651   MUS81_DEBHA Crossover junction endonuclease M...6587e-108     346     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
6Q59NG5    614   MUS81_CANAL Crossover junction endonuclease M...6525e-99     321     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
7Q7SD49    645   MUS81_NEUCR Crossover junction endonuclease m...6709e-62     222     28     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
8Q4INS6    581   MUS81_GIBZE Crossover junction endonuclease M...6381e-61     220     28     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
9Q4WYE5    596   MUS81_ASPFU Crossover junction endonuclease m...6481e-58     212     27     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
10P87231    608   MUS81_SCHPO Crossover junction endonuclease m...6362e-55     203     28     47GO:0048476; C:Holliday junction resolvase complex; IDA:PomBase.::GO:0005739; C:mitochondrion; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0008821; F:crossover junction endodeoxyribonuclease activity; IDA:PomBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0031573; P:intra-S DNA damage checkpoint; IDA:PomBase.::GO:0000711; P:meiotic DNA repair synthesis; IMP:PomBase.::GO:0000709; P:meiotic joint molecule formation; TAS:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IMP:PomBase.::GO:0006301; P:postreplication repair; TAS:PomBase.::GO:0031297; P:replication fork processing; TAS:PomBase.
11Q5B8L2    677   MUS81_EMENI Crossover junction endonuclease m...6567e-53     197     26     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
12Q551H0    920   MUS81_DICDI Probable crossover junction endon...2933e-24     111     30     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
13Q640B4    612   MUS81_XENTR Crossover junction endonuclease M...2420.000000000000003     82.8     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
14Q96NY9    551   MUS81_HUMAN Crossover junction endonuclease M...2230.000000004     63.2     25     44GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0048257; F:3'-flap endonuclease activity; IMP:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IMP:UniProtKB.
15Q4KM32    551   MUS81_RAT Crossover junction endonuclease MUS...2700.0000000002     67.4     23     41GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
16Q91ZJ0    551   MUS81_MOUSE Crossover junction endonuclease M...2330.0000000005     65.9     24     44GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
17Q7SXA9    604   MUS81_DANRE Crossover junction endonuclease M...2310.00000000000005     79     29     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
18P0CAF6    366   VF364_ASFK5 ERCC4 domain-containing protein E...1790.0002     47.8     26     49
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
19Q65151    364   VF364_ASFB7 ERCC4 domain-containing protein E...1800.0003     47     26     47
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
20P0CAF7    383   VF364_ASFM2 ERCC4 domain-containing protein E...1450.003     44.3     27     50
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
21P0CAF8    369   VF364_ASFP4 ERCC4 domain-containing protein E...1450.003     43.9     27     50
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
22P0CAF9    366   VF364_ASFWA ERCC4 domain-containing protein E...1450.003     43.9     27     50
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
23A5DFH6    247   RPIA_PICGU Ribose-5-phosphate isomerase OS=15...580.36     37     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004751; F:ribose-5-phosphate isomerase activity; IEA:EC.
GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IEA:InterPro.
24Q82XU6    467   DER_NITEU GTPase Der OS=Nitrosomonas europaea...1781.7     35.4     22     42
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
25Q5NVA9    575   EME1_PONAB Crossover junction endonuclease EM...632.1     35     29     56GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
26Q58900    778   Y1505_METJA Putative ATP-dependent RNA helica...1074.7     33.9     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:InterPro.
27Q8BJW7    570   EME1_MOUSE Crossover junction endonuclease EM...637.9     33.1     29     56GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
28Q96AY2    570   EME1_HUMAN Crossover junction endonuclease EM...878.9     33.1     29     51GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
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