Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR379W
Length:
1009
Number of sequences:
5887
Description:
YDR379W RGA2 SGDID:S000002787, Chr IV from 1230167-1233196, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q86IG9    566   GACH_DICDI Rho GTPase-activating protein gacH...2100.00000000000003     80.5     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
62Q5T5U3    1957   RHG21_HUMAN Rho GTPase-activating protein 21 ...2420.00000000000003     81.6     24     44GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051683; P:establishment of Golgi localization; IDA:BHF-UCL.::GO:0007030; P:Golgi organization; IMP:BHF-UCL.::GO:0051684; P:maintenance of Golgi location; IMP:BHF-UCL.::GO:0072384; P:organelle transport along microtubule; IMP:BHF-UCL.::GO:0007165; P:signal transduction; IEA:InterPro.
63P97393    1501   RHG05_MOUSE Rho GTPase-activating protein 5 O...2250.00000000000003     81.3     27     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0030335; P:positive regulation of cell migration; IMP:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:0008361; P:regulation of cell size; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
64Q6DFG0    1926   RH21A_XENLA Rho GTPase-activating protein 21-...2170.00000000000003     81.6     26     45GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
65Q9P227    1491   RHG23_HUMAN Rho GTPase-activating protein 23 ...2140.00000000000003     81.3     29     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
66P34288    1605   PAC1_CAEEL GTPase-activating protein pac-1 OS...2030.00000000000003     81.3     27     49GO:0030054; C:cell junction; IDA:WormBase.::GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010470; P:regulation of gastrulation; IMP:WormBase.::GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
67Q5PQJ5    1266   RHG29_RAT Rho GTPase-activating protein 29 OS...2350.00000000000003     81.3     26     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
68O43295    1099   SRGP3_HUMAN SLIT-ROBO Rho GTPase-activating p...2230.00000000000005     80.5     25     49GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
69O75044    1071   FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p...2070.00000000000008     79.7     27     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
70Q13459    2157   MYO9B_HUMAN Unconventional myosin-IXb OS=Homo...1940.00000000000009     80.1     29     50GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0043531; F:ADP binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
GO:0030048; P:actin filament-based movement; TAS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; IC:UniProtKB.
71Q6DFV3    1944   RHG21_MOUSE Rho GTPase-activating protein 21 ...2410.0000000000001     79.7     24     44GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
72Q7Z5H3    698   RHG22_HUMAN Rho GTPase-activating protein 22 ...2330.0000000000001     78.6     26     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
73Q8BL80    702   RHG22_MOUSE Rho GTPase-activating protein 22 ...2300.0000000000003     77.8     26     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74Q5U4T3    771   RHG26_XENLA Rho GTPase-activating protein 26 ...2060.0000000000003     77.8     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
75P0CAX5    802   OPHN1_RAT Oligophrenin-1 OS=Rattus norvegicus...2060.0000000000003     77.8     28     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
76Q812A2    1099   SRGP3_MOUSE SLIT-ROBO Rho GTPase-activating p...2230.0000000000003     77.8     25     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0007165; P:signal transduction; IEA:InterPro.
77A6QNS3    859   ABR_BOVIN Active breakpoint cluster region-re...1940.0000000000004     77.4     28     47
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
78O94988    1023   FA13A_HUMAN Protein FAM13A OS=Homo sapiens (H...2750.0000000000004     77.4     27     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
79Q5SSL4    859   ABR_MOUSE Active breakpoint cluster region-re...1920.0000000000005     77.4     29     47GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
80Q9QY06    2114   MYO9B_MOUSE Unconventional myosin-IXb OS=Mus ...1940.0000000000005     77.4     28     49GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
81B2RTY4    2548   MYO9A_HUMAN Unconventional myosin-IXa OS=Homo...2000.0000000000006     77.4     30     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016461; C:unconventional myosin complex; NAS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007601; P:visual perception; TAS:ProtInc.
82Q7YQL5    802   OPHN1_PONPY Oligophrenin-1 OS=Pongo pygmaeus ...2090.0000000000007     76.6     27     49GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
83Q7YQL6    802   OPHN1_PANTR Oligophrenin-1 OS=Pan troglodytes...2090.0000000000007     76.6     27     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
84Q12979    859   ABR_HUMAN Active breakpoint cluster region-re...1920.0000000000007     76.6     28     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
85Q07960    439   RHG01_HUMAN Rho GTPase-activating protein 1 O...2230.0000000000007     75.5     24     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
86B5DFQ4    759   RHG26_XENTR Rho GTPase-activating protein 26 ...2060.0000000000008     76.3     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
87Q63358    1980   MYO9B_RAT Unconventional myosin-IXb OS=Rattus...1940.0000000000008     77     28     49GO:0005884; C:actin filament; IDA:RGD.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:RGD.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0001726; C:ruffle; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051015; F:actin filament binding; IDA:RGD.::GO:0030898; F:actin-dependent ATPase activity; IDA:RGD.::GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0043008; F:ATP-dependent protein binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0007266; P:Rho protein signal transduction; IDA:RGD.
88O60890    802   OPHN1_HUMAN Oligophrenin-1 OS=Homo sapiens (H...2090.0000000000008     76.3     27     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:ProtInc.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc.
89Q9Z1N3    2626   MYO9A_RAT Unconventional myosin-IXa OS=Rattus...2000.000000000001     76.3     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
90Q8AVG0    862   ABR_XENLA Active breakpoint cluster region-re...1920.000000000001     75.9     29     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
91A4II46    862   ABR_XENTR Active breakpoint cluster region-re...1920.000000000001     75.5     28     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
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