Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR379W
Length:
1009
Number of sequences:
5887
Description:
YDR379W RGA2 SGDID:S000002787, Chr IV from 1230167-1233196, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331Q5M8V8    158   RBTN2_XENTR Rhombotin-2 OS=Xenopus tropicalis...562.3     34.3     29     48GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
332P20271    351   HM14_CAEEL Homeobox protein ceh-14 OS=Caenorh...1000.012     42.7     27     46GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0016048; P:detection of temperature stimulus; IMP:UniProtKB.::GO:0030182; P:neuron differentiation; IMP:UniProtKB.::GO:0040040; P:thermosensory behavior; IMP:WormBase.
333O43052    1150   RGA1_SCHPO Rho-type GTPase-activating protein...1830.013     43.1     20     47GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005100; F:Rho GTPase activator activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030036; P:actin cytoskeleton organization; IMP:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
334P53671    638   LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapie...2580.02     42.4     24     37GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042325; P:regulation of phosphorylation; IEA:InterPro.
335Q71QF9    831   PRIC1_RAT Prickle-like protein 1 OS=Rattus no...1140.015     43.1     21     39GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0008134; F:transcription factor binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IDA:RGD.
336P53409    363   ISL3_ONCTS Insulin gene enhancer protein ISL-...1000.016     42.4     24     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
337Q9H2C1    402   LHX5_HUMAN LIM/homeobox protein Lhx5 OS=Homo ...2140.51     37.7     21     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
338O54785    638   LIMK2_MOUSE LIM domain kinase 2 OS=Mus muscul...1810.019     42.7     23     41GO:0005801; C:cis-Golgi network; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007283; P:spermatogenesis; IMP:MGI.
339P36200    395   LHX3_XENLA LIM/homeobox protein Lhx3 OS=Xenop...980.019     42.4     26     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
340Q3U5C7    832   PRIC1_MOUSE Prickle-like protein 1 OS=Mus mus...1140.019     42.7     21     39GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
341Q96MT3    831   PRIC1_HUMAN Prickle-like protein 1 OS=Homo sa...1140.02     42.7     21     39GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:2000691; P:negative regulation of cardiac muscle cell myoblast differentiation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0001843; P:neural tube closure; IMP:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.::GO:0006606; P:protein import into nucleus; IDA:UniProtKB.
342A2I8Z7    377   LHX9_ASTFA LIM/homeobox protein Lhx9 OS=Astya...427.3     33.9     38     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
343Q80W90    388   LHX9_RAT LIM/homeobox protein Lhx9 OS=Rattus ...1000.021     42     22     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
344P61376    402   LHX5_RAT LIM/homeobox protein Lhx5 OS=Rattus ...2141.1     36.6     21     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
345P61375    402   LHX5_MOUSE LIM/homeobox protein Lhx5 OS=Mus m...2141.1     36.6     21     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021846; P:cell proliferation in forebrain; IMP:MGI.::GO:0021702; P:cerebellar Purkinje cell differentiation; IGI:MGI.::GO:0021937; P:cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; IGI:MGI.::GO:0021879; P:forebrain neuron differentiation; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0021527; P:spinal cord association neuron differentiation; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
346P50480    360   ISL2_RAT Insulin gene enhancer protein ISL-2 ...1010.023     42     24     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
347P25801    158   RBTN2_MOUSE Rhombotin-2 OS=Mus musculus (Mous...561.7     34.7     29     48GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0043234; C:protein complex; IPI:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035162; P:embryonic hemopoiesis; IGI:MGI.::GO:0045647; P:negative regulation of erythrocyte differentiation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
348P25791    158   RBTN2_HUMAN Rhombotin-2 OS=Homo sapiens (Huma...561.7     34.7     29     48GO:0005667; C:transcription factor complex; IDA:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0048037; F:cofactor binding; IPI:BHF-UCL.::GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.::GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IDA:BHF-UCL.
349Q1LZ94    158   RBTN2_BOVIN Rhombotin-2 OS=Bos taurus (Bovine...561.7     34.7     29     48
GO:0008270; F:zinc ion binding; IEA:InterPro.
350Q62908    193   CSRP2_RAT Cysteine and glycine-rich protein 2...570.03     40.4     35     46GO:0005634; C:nucleus; IDA:RGD.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045445; P:myoblast differentiation; IEP:RGD.
351P97314    193   CSRP2_MOUSE Cysteine and glycine-rich protein...570.03     40.4     35     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
352Q16527    193   CSRP2_HUMAN Cysteine and glycine-rich protein...570.03     40.4     35     46GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
353Q32LE9    193   CSRP2_BOVIN Cysteine and glycine-rich protein...570.03     40.4     35     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
354P53669    647   LIMK1_RAT LIM domain kinase 1 OS=Rattus norve...496.1     34.3     33     49GO:0044295; C:axonal growth cone; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.
355P53406    359   ISL2A_DANRE Insulin gene enhancer protein isl...1000.027     41.6     24     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048676; P:axon extension involved in development; IMP:ZFIN.::GO:0048665; P:neuron fate specification; IMP:ZFIN.
356Q9PTJ3    159   RBTN2_DANRE Rhombotin-2 OS=Danio rerio (Zebra...564.7     33.5     29     45GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001568; P:blood vessel development; IMP:ZFIN.::GO:0035162; P:embryonic hemopoiesis; IMP:ZFIN.::GO:0030218; P:erythrocyte differentiation; IGI:ZFIN.
357Q6P7E4    419   PDLI7_DANRE PDZ and LIM domain protein 7 OS=D...1180.66     37.4     28     42GO:0031941; C:filamentous actin; IDA:ZFIN.::GO:0048471; C:perinuclear region of cytoplasm; IDA:ZFIN.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003294; P:atrial ventricular junction remodeling; IMP:ZFIN.::GO:0003190; P:atrioventricular valve formation; IMP:ZFIN.::GO:0001947; P:heart looping; IMP:ZFIN.::GO:0001756; P:somitogenesis; IMP:ZFIN.
358Q05158    194   CSRP2_COTJA Cysteine and glycine-rich protein...590.1     38.9     24     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
359P50460    194   CSRP2_CHICK Cysteine and glycine-rich protein...590.1     38.9     24     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
360Q1LWV4    396   LHX9_DANRE LIM/homeobox protein Lhx9 OS=Danio...465.2     34.3     37     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
361Q9NQ69    397   LHX9_HUMAN LIM/homeobox protein Lhx9 OS=Homo ...1000.03     41.6     22     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
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