Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR379W
Length:
1009
Number of sequences:
5887
Description:
YDR379W RGA2 SGDID:S000002787, Chr IV from 1230167-1233196, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q91V57    459   CHIN_MOUSE N-chimaerin OS=Mus musculus (Mouse...2351e-16     87.4     27     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; IMP:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.
32Q6GPD0    1940   RHG32_XENLA Rho GTPase-activating protein 32 ...2302e-16     89     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
33Q71M21    1902   RH21B_XENLA Rho GTPase-activating protein 21-...2192e-16     88.6     27     46GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
34Q6DE55    1107   HMHA1_XENLA Minor histocompatibility protein ...2322e-16     88.6     28     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
35Q91YM2    1499   RHG35_MOUSE Rho GTPase-activating protein 35 ...2183e-16     87.8     30     51GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:MGI.
GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; TAS:MGI.::GO:0043116; P:negative regulation of vascular permeability; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
36P81128    1513   RHG35_RAT Rho GTPase-activating protein 35 OS...2186e-16     87     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37Q9NRY4    1513   RHG35_HUMAN Rho GTPase-activating protein 35 ...2187e-16     86.7     30     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:Reactome.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; TAS:ProtInc.
38Q2M1Z3    1444   RHG31_HUMAN Rho GTPase-activating protein 31 ...2137e-16     86.7     26     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
39Q80YF9    1305   RHG33_MOUSE Rho GTPase-activating protein 33 ...2298e-16     86.3     24     48GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
40A2RUV4    1935   RHG21_XENTR Rho GTPase-activating protein 21 ...2190.000000000000001     86.3     26     46GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
41P83509    1500   RHG35_CANFA Rho GTPase-activating protein 35 ...2180.000000000000001     86.3     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042478; P:regulation of eye photoreceptor cell development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42Q5RB40    1163   HMHA1_PONAB Minor histocompatibility protein ...2290.000000000000001     85.5     26     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
43O14559    1287   RHG33_HUMAN Rho GTPase-activating protein 33 ...2290.000000000000002     85.5     25     48
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
44A6X8Z5    1425   RHG31_MOUSE Rho GTPase-activating protein 31 ...2130.000000000000002     85.5     26     46GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0030027; C:lamellipodium; IDA:MGI.
GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI.
GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
45Q8CGF1    1266   RHG29_MOUSE Rho GTPase-activating protein 29 ...2350.000000000000002     85.1     27     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
46P52757    468   CHIO_HUMAN Beta-chimaerin OS=Homo sapiens (Hu...2070.000000000000003     83.2     29     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
47Q03070    295   CHIO_RAT Beta-chimaerin OS=Rattus norvegicus ...2070.000000000000003     81.3     28     47GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001565; F:phorbol ester receptor activity; TAS:RGD.::GO:0030675; F:Rac GTPase activator activity; IDA:RGD.
GO:0001675; P:acrosome assembly; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
48A7YY57    1269   RHG29_BOVIN Rho GTPase-activating protein 29 ...2370.000000000000004     84.3     27     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
49Q92619    1136   HMHA1_HUMAN Minor histocompatibility protein ...2290.000000000000004     84.3     25     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
50Q811P8    2089   RHG32_MOUSE Rho GTPase-activating protein 32 ...2330.000000000000004     84.3     28     49GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005938; C:cell cortex; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
51A7KAX9    2087   RHG32_HUMAN Rho GTPase-activating protein 32 ...2330.000000000000004     84.3     28     49GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
52Q80XD1    332   CHIO_MOUSE Beta-chimaerin OS=Mus musculus (Mo...2070.000000000000004     81.3     28     47GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
53Q3TBD2    1116   HMHA1_MOUSE Minor histocompatibility protein ...2320.000000000000005     83.6     25     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
54Q54TH9    721   GACY_DICDI Rho GTPase-activating protein gacY...2080.000000000000006     83.2     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
55Q52LW3    1261   RHG29_HUMAN Rho GTPase-activating protein 29 ...2380.000000000000007     83.6     28     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.
GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
56Q91Z67    1071   FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating p...2070.00000000000002     82     28     48GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
57Q69ZH9    1483   RHG23_MOUSE Rho GTPase-activating protein 23 ...2140.00000000000002     82     29     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
58Q13017    1502   RHG05_HUMAN Rho GTPase-activating protein 5 O...2250.00000000000002     81.6     28     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
59Q7Z6B7    1085   SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating p...2250.00000000000003     81.3     27     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0007411; P:axon guidance; TAS:Reactome.
60Q91Z69    1062   SRGP1_MOUSE SLIT-ROBO Rho GTPase-activating p...2100.00000000000003     81.3     29     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0017048; F:Rho GTPase binding; IDA:MGI.
GO:0016477; P:cell migration; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
61Q86IG9    566   GACH_DICDI Rho GTPase-activating protein gacH...2100.00000000000003     80.5     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
records
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