Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR379W
Length:
1009
Number of sequences:
5887
Description:
YDR379W RGA2 SGDID:S000002787, Chr IV from 1230167-1233196, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q9NR12    457   PDLI7_HUMAN PDZ and LIM domain protein 7 OS=H...1120.003     44.7     28     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
302A2PZF9    379   LHX9_GLARU LIM/homeobox protein Lhx9 OS=Gland...1260.003     44.7     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
303Q8UUU2    722   P85AA_XENLA Phosphatidylinositol 3-kinase reg...1750.003     45.1     24     45GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.
GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB.
GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.
304Q8TE12    382   LMX1A_HUMAN LIM homeobox transcription factor...1070.003     44.7     25     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
305Q9Z1Z9    457   PDLI7_RAT PDZ and LIM domain protein 7 OS=Rat...1120.014     42.7     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0045669; P:positive regulation of osteoblast differentiation; IDA:RGD.
306P29673    469   APTE_DROME Protein apterous OS=Drosophila mel...950.003     44.7     25     40GO:0005634; C:nucleus; IDA:FlyBase.
GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0045165; P:cell fate commitment; NAS:FlyBase.::GO:0007451; P:dorsal/ventral lineage restriction, imaginal disc; TAS:FlyBase.::GO:0007559; P:histolysis; IMP:FlyBase.::GO:0036011; P:imaginal disc-derived leg segmentation; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; TAS:FlyBase.::GO:0007526; P:larval somatic muscle development; IMP:FlyBase.::GO:0007479; P:leg disc proximal/distal pattern formation; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IMP:FlyBase.::GO:0048190; P:wing disc dorsal/ventral pattern formation; IMP:FlyBase.
307Q8CI51    591   PDLI5_MOUSE PDZ and LIM domain protein 5 OS=M...1190.072     40.8     23     38GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB.
308O14639    778   ABLM1_HUMAN Actin-binding LIM protein 1 OS=Ho...930.089     40.4     26     44GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc.
309A5H447    663   ZYX_XENLA Zyxin OS=Xenopus laevis (African cl...589.9     33.9     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB.
GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
310Q8BGT6    870   MILK1_MOUSE MICAL-like protein 1 OS=Mus muscu...800.005     44.7     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
311Q90XH3    158   RBTN2_XENLA Rhombotin-2 OS=Xenopus laevis (Af...960.005     42.4     22     40GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030218; P:erythrocyte differentiation; IGI:UniProtKB.
312Q55DW9    1043   GACZ_DICDI Rho GTPase-activating protein gacZ...1770.005     44.7     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
313Q55GP8    684   GACO_DICDI Rho GTPase-activating protein gacO...1770.005     44.3     23     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
314Q679P3    416   PDLI7_CHICK PDZ and LIM domain protein 7 OS=G...1120.015     42.7     28     42GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.
315P53412    395   LHX3_CHICK LIM/homeobox protein Lhx3 OS=Gallu...522.1     35.8     27     48
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
316Q8QFP8    662   LIMK1_CHICK LIM domain kinase 1 OS=Gallus gal...1290.006     44.3     23     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
317Q923Q2    1113   STA13_MOUSE StAR-related lipid transfer prote...1590.006     44.3     27     45GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
318Q71FD7    375   FBLI1_MOUSE Filamin-binding LIM protein 1 OS=...1050.007     43.5     29     50GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB.
GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB.
319Q9JKU8    382   LMX1A_MOUSE LIM homeobox transcription factor...980.008     43.5     23     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0021953; P:central nervous system neuron differentiation; IMP:MGI.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021542; P:dentate gyrus development; IMP:MGI.::GO:0071542; P:dopaminergic neuron differentiation; IMP:MGI.::GO:0030901; P:midbrain development; IMP:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0001558; P:regulation of cell growth; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
320Q8K031    1019   STAR8_MOUSE StAR-related lipid transfer prote...2030.008     43.9     24     42GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
321Q9JKS4    723   LDB3_MOUSE LIM domain-binding protein 3 OS=Mu...1150.008     43.9     25     40GO:0005856; C:cytoskeleton; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI.
GO:0005080; F:protein kinase C binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
322Q04650    382   LMX1A_MESAU LIM homeobox transcription factor...980.008     43.5     23     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
323Q7TQJ8    398   WTIP_MOUSE Wilms tumor protein 1-interacting ...1230.009     43.5     24     41GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
324P53407    358   ISL2B_DANRE Insulin gene enhancer protein isl...1000.009     43.1     24     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
325Q96A47    359   ISL2_HUMAN Insulin gene enhancer protein ISL-...1450.009     43.1     23     37GO:0005634; C:nucleus; IC:BHF-UCL.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048935; P:peripheral nervous system neuron development; TAS:BHF-UCL.
326Q5F3G0    495   RHG19_CHICK Rho GTPase-activating protein 19 ...2030.01     43.5     26     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
327Q54VW7    1203   GACGG_DICDI Rho GTPase-activating protein gac...1620.01     43.9     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
328A0JNI8    397   LHX9_BOVIN LIM/homeobox protein Lhx9 OS=Bos t...1000.01     43.1     23     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
329Q9CXV0    359   ISL2_MOUSE Insulin gene enhancer protein ISL-...1450.011     42.7     23     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:MGI.::GO:0021520; P:spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021524; P:visceral motor neuron differentiation; IMP:MGI.
330Q54Y72    338   GACA_DICDI Rho GTPase-activating protein gacA...870.011     42.7     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
331Q5M8V8    158   RBTN2_XENTR Rhombotin-2 OS=Xenopus tropicalis...562.3     34.3     29     48GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
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