Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR379W
Length:
1009
Number of sequences:
5887
Description:
YDR379W RGA2 SGDID:S000002787, Chr IV from 1230167-1233196, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271Q91XC0    547   AJUBA_MOUSE LIM domain-containing protein aju...1130.0009     46.6     27     44GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016339; P:calcium-dependent cell-cell adhesion; IMP:MGI.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IMP:MGI.::GO:0048041; P:focal adhesion assembly; IMP:MGI.::GO:0046474; P:glycerophospholipid biosynthetic process; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0033673; P:negative regulation of kinase activity; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0031328; P:positive regulation of cellular biosynthetic process; IMP:MGI.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:MGI.::GO:0030334; P:regulation of cell migration; IDA:MGI.::GO:0043087; P:regulation of GTPase activity; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035313; P:wound healing, spreading of epidermal cells; IMP:MGI.
272Q9P2N2    729   RHG28_HUMAN Rho GTPase-activating protein 28 ...2100.001     47     23     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
273Q3KRB8    267   RHGBB_HUMAN Rho GTPase-activating protein 11B...1730.001     45.8     24     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
274Q90WV2    832   PRI1B_XENLA Prickle-like protein 1-B OS=Xenop...960.001     47     26     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.
275Q99JW4    325   LIMS1_MOUSE LIM and senescent cell antigen-li...1171.7     35.8     24     43GO:0005925; C:focal adhesion; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0007160; P:cell-matrix adhesion; IMP:MGI.::GO:0043009; P:chordate embryonic development; IMP:MGI.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.
276A1ZA47    2194   ZASP_DROME PDZ and LIM domain protein Zasp OS...1120.001     47     27     41GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005927; C:muscle tendon junction; IDA:FlyBase.::GO:0030018; C:Z disc; IDA:FlyBase.
GO:0003779; F:actin binding; IPI:UniProtKB.::GO:0051371; F:muscle alpha-actinin binding; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061061; P:muscle structure development; IMP:FlyBase.::GO:0001952; P:regulation of cell-matrix adhesion; IMP:UniProtKB.
277Q90421    398   LHX3_DANRE LIM/homeobox protein Lhx3 OS=Danio...990.001     46.2     26     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
278E1BKA3    548   AJUBA_BOVIN LIM domain-containing protein aju...1130.001     46.6     27     44GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
279Q9VDG2    625   RLIP_DROME RalA-binding protein 1 OS=Drosophi...1990.001     46.6     25     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:FlyBase.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
280Q9U1I1    785   ESN_DROME Protein espinas OS=Drosophila melan...1000.001     46.6     26     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070593; P:dendrite self-avoidance; IMP:FlyBase.
281Q62523    564   ZYX_MOUSE Zyxin OS=Mus musculus (Mouse). GN=Z...1030.001     46.2     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
282Q8K4G5    861   ABLM1_MOUSE Actin-binding LIM protein 1 OS=Mu...930.03     42     26     44GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
283P53776    390   LHX4_MOUSE LIM/homeobox protein Lhx4 OS=Mus m...980.001     45.8     24     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0021526; P:medial motor column neuron differentiation; IGI:MGI.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
284Q0VA45    674   ZYX_XENTR Zyxin OS=Xenopus tropicalis (Wester...980.001     46.2     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB.
GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
285Q969G2    390   LHX4_HUMAN LIM/homeobox protein Lhx4 OS=Homo ...980.001     45.8     24     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
286Q3SX40    424   PDLI7_BOVIN PDZ and LIM domain protein 7 OS=B...1120.007     43.9     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.
287Q8UVR3    400   LMX1B_XENLA LIM homeobox transcription factor...1070.002     45.8     23     42GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0072013; P:glomus development; IMP:UniProtKB.::GO:0030182; P:neuron differentiation; IMP:UniProtKB.::GO:0039020; P:pronephric nephron tubule development; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
288Q62920    591   PDLI5_RAT PDZ and LIM domain protein 5 OS=Rat...1190.063     40.8     23     38GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0042805; F:actinin binding; IDA:UniProtKB.::GO:0005080; F:protein kinase C binding; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IMP:RGD.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007507; P:heart development; NAS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; IDA:UniProtKB.::GO:0051963; P:regulation of synapse assembly; IDA:UniProtKB.
289Q96HC4    596   PDLI5_HUMAN PDZ and LIM domain protein 5 OS=H...1190.052     41.2     23     38GO:0015629; C:actin cytoskeleton; IDA:LIFEdb.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0042805; F:actinin binding; ISS:UniProtKB.::GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB.
290A6NIX2    430   WTIP_HUMAN Wilms tumor protein 1-interacting ...1230.002     45.4     24     41GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0000932; C:cytoplasmic mRNA processing body; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0035195; P:gene silencing by miRNA; IMP:MGI.::GO:0035331; P:negative regulation of hippo signaling cascade; IDA:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
291Q28FG2    833   PRIC1_XENTR Prickle-like protein 1 OS=Xenopus...1140.002     45.8     23     40GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
292Q6INU3    421   PDLI7_XENLA PDZ and LIM domain protein 7 OS=X...1120.058     40.8     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
293Q3TJD7    457   PDLI7_MOUSE PDZ and LIM domain protein 7 OS=M...1120.011     43.1     27     41GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.::GO:0001725; C:stress fiber; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IPI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.
294Q54BF1    1132   GACE_DICDI Rho GTPase-activating protein gacE...2040.002     46.2     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
295Q6P4F7    1023   RHGBA_HUMAN Rho GTPase-activating protein 11A...1670.002     45.8     25     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
296P53408    358   ISL2A_ONCTS Insulin gene enhancer protein ISL...1630.002     45.1     23     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
297Q92502    1023   STAR8_HUMAN StAR-related lipid transfer prote...2170.002     45.8     25     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
298Q9P2F6    1191   RHG20_HUMAN Rho GTPase-activating protein 20 ...2530.002     45.8     21     40GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
299Q6REY9    1182   RHG20_RAT Rho GTPase-activating protein 20 OS...2460.002     45.8     21     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; TAS:RGD.
GO:0035023; P:regulation of Rho protein signal transduction; TAS:RGD.::GO:0007165; P:signal transduction; IEA:InterPro.
300Q8BRH3    494   RHG19_MOUSE Rho GTPase-activating protein 19 ...1990.003     45.1     26     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
301Q9NR12    457   PDLI7_HUMAN PDZ and LIM domain protein 7 OS=H...1120.003     44.7     28     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
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