Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR379W
Length:
1009
Number of sequences:
5887
Description:
YDR379W RGA2 SGDID:S000002787, Chr IV from 1230167-1233196, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q15942    572   ZYX_HUMAN Zyxin OS=Homo sapiens (Human). GN=Z...1210.00004     51.2     27     47GO:0005913; C:cell-cell adherens junction; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
212Q17R89    818   RHG44_HUMAN Rho GTPase-activating protein 44 ...2030.00004     51.6     23     43GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
213Q2YDK0    284   FHL5_BOVIN Four and a half LIM domains protei...635     34.3     25     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
214P53666    642   LIMK2_CHICK LIM domain kinase 2 OS=Gallus gal...1790.00004     51.2     24     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
215A9LS46    690   WTIP_XENLA Wilms tumor protein 1-interacting ...1100.00005     51.2     26     47GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
216Q2KI95    279   FHL2_BOVIN Four and a half LIM domains protei...931.6     35.8     25     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
217Q6DJ06    165   LMO42_XENTR LIM domain transcription factor L...1000.00005     48.1     24     37
GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
218P35688    1017   LRG1_YEAST Rho-GTPase-activating protein LRG1...474.7     35     32     49GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005100; F:Rho GTPase activator activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009272; P:fungal-type cell wall biogenesis; IGI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
219Q7QJT4    923   PRIC1_ANOGA Protein prickle OS=Anopheles gamb...953.8     35     25     44GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
220B7ZUL2    593   LIMD1_XENTR LIM domain-containing protein 1 O...1200.00006     50.8     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
221P61969    165   LMO4_MOUSE LIM domain transcription factor LM...1000.00006     48.1     24     37GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0001158; F:enhancer sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031333; P:negative regulation of protein complex assembly; IDA:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0050865; P:regulation of cell activation; IMP:MGI.::GO:0042659; P:regulation of cell fate specification; IMP:MGI.::GO:0021527; P:spinal cord association neuron differentiation; IGI:MGI.::GO:0021522; P:spinal cord motor neuron differentiation; IDA:MGI.::GO:0048538; P:thymus development; IGI:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:MGI.::GO:0021514; P:ventral spinal cord interneuron differentiation; IDA:MGI.::GO:0003281; P:ventricular septum development; IMP:MGI.
222P61968    165   LMO4_HUMAN LIM domain transcription factor LM...1000.00006     48.1     24     37GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001843; P:neural tube closure; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
223Q3SWZ8    165   LMO4_BOVIN LIM domain transcription factor LM...1000.00006     48.1     24     37
GO:0008270; F:zinc ion binding; IEA:InterPro.
224Q801P0    171   LMO4B_XENLA LIM domain transcription factor L...1000.00007     47.8     24     37
GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
225Q86I31    885   GACFF_DICDI Rho GTPase-activating protein gac...1770.00008     50.4     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
226Q5XI07    632   LPP_RAT Lipoma-preferred partner homolog OS=R...1025.8     34.7     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
227Q63787    724   P85A_RAT Phosphatidylinositol 3-kinase regula...1750.00009     50.1     28     44GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:RGD.::GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IDA:RGD.::GO:0051117; F:ATPase binding; IPI:RGD.::GO:0005516; F:calmodulin binding; IPI:RGD.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD.
GO:0071398; P:cellular response to fatty acid; IEP:RGD.::GO:0006006; P:glucose metabolic process; IMP:RGD.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045776; P:negative regulation of blood pressure; IMP:RGD.::GO:0022408; P:negative regulation of cell-cell adhesion; IMP:RGD.::GO:0010459; P:negative regulation of heart rate; IMP:RGD.::GO:0045861; P:negative regulation of proteolysis; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0071548; P:response to dexamethasone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009750; P:response to fructose stimulus; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0010040; P:response to iron(II) ion; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0001878; P:response to yeast; IEP:RGD.
228O35115    279   FHL2_RAT Four and a half LIM domains protein ...910.33     38.1     24     40GO:0031430; C:M band; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:RGD.
GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
229O70433    279   FHL2_MOUSE Four and a half LIM domains protei...910.33     38.1     24     40GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0055014; P:atrial cardiac muscle cell development; IEP:BHF-UCL.::GO:0060347; P:heart trabecula formation; IEP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IEP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0055015; P:ventricular cardiac muscle cell development; IEP:BHF-UCL.
230Q04584    542   ZYX_CHICK Zyxin OS=Gallus gallus (Chicken). G...1070.00009     50.1     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
231Q54XE8    576   GACP_DICDI Rho GTPase-activating protein gacP...1090.0001     49.7     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
232P36198    426   LHX2_RAT LIM/homeobox protein Lhx2 OS=Rattus ...1060.0001     49.3     25     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
233A8DZE6    648   WTIP_DANRE Wilms tumor protein 1-interacting ...1100.0001     49.3     26     45GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
234Q8BFW7    613   LPP_MOUSE Lipoma-preferred partner homolog OS...1520.0001     49.3     24     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
235Q5F464    604   LPP_CHICK Lipoma-preferred partner homolog OS...1520.0002     49.3     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
236Q90Z06    835   PRI1A_XENLA Prickle-like protein 1-A OS=Xenop...1180.0002     49.3     25     40GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; IMP:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; IMP:UniProtKB.::GO:0001736; P:establishment of planar polarity; IMP:UniProtKB.
237Q25132    692   LHX3_HALRO LIM/homeobox protein Lhx3 OS=Haloc...1570.0002     49.3     25     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
238P48059    325   LIMS1_HUMAN LIM and senescent cell antigen-li...1171.7     35.8     24     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0007569; P:cell aging; TAS:ProtInc.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.
239Q9VY77    728   AJUBA_DROME LIM domain-containing protein jub...1100.0002     48.9     24     44GO:0005912; C:adherens junction; IDA:FlyBase.
GO:0003779; F:actin binding; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035329; P:hippo signaling cascade; IMP:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.
240Q8BN58    729   RHG28_MOUSE Rho GTPase-activating protein 28 ...2100.0002     48.9     24     44
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
241Q8SSN9    1140   GACF_DICDI Rho GTPase-activating protein gacF...2060.0002     48.9     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
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