Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR379W
Length:
1009
Number of sequences:
5887
Description:
YDR379W RGA2 SGDID:S000002787, Chr IV from 1230167-1233196, Genome Release 64-1-1, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q8K2H3    851   FA13B_MOUSE Protein FAM13B OS=Mus musculus (M...2000.0000002     58.9     24     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
152Q13643    280   FHL3_HUMAN Four and a half LIM domains protei...1190.018     42     24     37
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007517; P:muscle organ development; TAS:ProtInc.
153Q3ZBI6    280   FHL3_BOVIN Four and a half LIM domains protei...593.4     34.7     27     41
GO:0008270; F:zinc ion binding; IEA:InterPro.
154Q9VX32    1561   RG190_DROME Rho GTPase-activating protein 190...1800.0000003     58.5     29     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
155Q15311    655   RBP1_HUMAN RalA-binding protein 1 OS=Homo sap...2010.0000003     58.2     25     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IDA:UniProtKB.
GO:0043492; F:ATPase activity, coupled to movement of substances; IDA:UniProtKB.::GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.::GO:0006810; P:transport; IDA:UniProtKB.
156Q9NYF5    915   FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H...2000.0000003     58.2     24     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
157Q8K0Q5    663   RHG18_MOUSE Rho GTPase-activating protein 18 ...1800.0000004     57.8     27     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
158Q62796    647   RBP1_RAT RalA-binding protein 1 OS=Rattus nor...1900.0000004     57.8     25     47GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IMP:RGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IDA:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IPI:RGD.
159P32873    1128   BEM3_YEAST GTPase-activating protein BEM3 OS=...2420.0000005     57.8     26     47GO:0005938; C:cell cortex; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD.
GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:SGD.::GO:0007165; P:signal transduction; IEA:InterPro.
160Q54YV1    817   GACII_DICDI Rho GTPase-activating protein gac...1860.0000005     57.4     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
161Q13642    323   FHL1_HUMAN Four and a half LIM domains protei...643     35     25     42GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; NAS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
162Q99MB5    145   LMO3_RAT LIM domain only protein 3 OS=Rattus ...1380.0000006     54.3     23     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
163Q8JFQ2    155   RBTN1_DANRE Rhombotin-1 OS=Danio rerio (Zebra...1360.0000008     53.9     24     39GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
164P25800    156   RBTN1_HUMAN Rhombotin-1 OS=Homo sapiens (Huma...1360.0000008     53.5     24     39GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
165Q3B8H4    156   RBTN1_XENLA Rhombotin-1 OS=Xenopus laevis (Af...1360.0000009     53.5     24     39GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
166Q54SL6    531   GACQ_DICDI Rho GTPase-activating protein gacQ...2290.0000009     56.2     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
167O54834    987   RHG06_MOUSE Rho GTPase-activating protein 6 O...1900.000001     56.6     25     44GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; IDA:MGI.::GO:0048041; P:focal adhesion assembly; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
168Q5RBW7    145   LMO3_PONAB LIM domain only protein 3 OS=Pongo...1260.000001     53.1     23     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
169Q8BZL8    145   LMO3_MOUSE LIM domain only protein 3 OS=Mus m...1260.000001     53.1     23     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
170Q8TAP4    145   LMO3_HUMAN LIM domain only protein 3 OS=Homo ...1260.000001     53.1     23     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
171Q2KIA3    145   LMO3_BOVIN LIM domain only protein 3 OS=Bos t...1260.000001     53.1     23     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
172P26450    724   P85A_MOUSE Phosphatidylinositol 3-kinase regu...1750.000001     56.2     29     45GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:MGI.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.
GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0034644; P:cellular response to UV; IMP:MGI.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0001953; P:negative regulation of cell-matrix adhesion; IGI:MGI.::GO:0045671; P:negative regulation of osteoclast differentiation; IGI:MGI.::GO:0051531; P:NFAT protein import into nucleus; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030335; P:positive regulation of cell migration; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI.
173O43182    974   RHG06_HUMAN Rho GTPase-activating protein 6 O...1900.000001     56.6     25     44GO:0005884; C:actin filament; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0016004; F:phospholipase activator activity; IDA:BHF-UCL.::GO:0043274; F:phospholipase binding; IPI:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0030041; P:actin filament polymerization; NAS:UniProtKB.::GO:0007202; P:activation of phospholipase C activity; IDA:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; IMP:BHF-UCL.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:BHF-UCL.::GO:0007266; P:Rho protein signal transduction; NAS:UniProtKB.
174Q62172    648   RBP1_MOUSE RalA-binding protein 1 OS=Mus musc...1800.000001     56.2     27     48GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; ISS:UniProtKB.
GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
175Q9R059    289   FHL3_MOUSE Four and a half LIM domains protei...1300.35     37.7     21     35
GO:0008270; F:zinc ion binding; IEA:InterPro.
176Q86NH1    987   SYD1_CAEEL Rho GTPase-activating protein syd-...1960.000001     56.2     28     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0042734; C:presynaptic membrane; IDA:WormBase.
GO:0005100; F:Rho GTPase activator activity; IMP:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; IMP:UniProtKB.::GO:0008088; P:axon cargo transport; IGI:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:WormBase.::GO:0040011; P:locomotion; IGI:WormBase.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
177Q61CA4    962   SYD1_CAEBR Rho GTPase-activating protein syd-...1970.000002     56.2     27     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; ISS:UniProtKB.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
178Q74ZH7    1013   BEM3_ASHGO GTPase-activating protein BEM3 OS=...1860.000002     56.2     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
179Q9PT60    655   RBP1A_XENLA RalA-binding protein 1-A OS=Xenop...1800.000002     55.8     27     48GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.
180Q503U0    145   LMO3_DANRE LIM domain only protein 3 OS=Danio...1260.000002     52.8     23     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
181Q9YH16    156   LMO3_XENLA LIM domain only protein 3 OS=Xenop...1260.000002     52.8     23     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
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