| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | P39960 | 2167 | BEM2_YEAST GTPase-activating protein BEM2/IPL... | 235 | 0.0000000004 | 68.2 | 26 | 46 | GO:0005938; C:cell cortex; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD.::GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 122 | Q9WUH4 | 280 | FHL1_RAT Four and a half LIM domains protein ... | 64 | 3.7 | 34.7 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 123 | P97447 | 280 | FHL1_MOUSE Four and a half LIM domains protei... | 64 | 0.45 | 37.4 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 124 | Q10164 | 1275 | RGA2_SCHPO Probable Rho-type GTPase-activatin... | 204 | 0.0000000005 | 67.8 | 29 | 47 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 125 | Q8BZ05 | 1703 | ARAP2_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 210 | 0.0000000005 | 67.8 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 126 | P38339 | 666 | RGD1_YEAST RHO GTPase-activating protein RGD1... | 190 | 0.0000000005 | 67 | 29 | 47 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005933; C:cellular bud; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IMP:SGD.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:SGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IMP:SGD.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007231; P:osmosensory signaling pathway; IGI:SGD.::GO:0001101; P:response to acid; IMP:SGD. | 127 | Q96P48 | 1450 | ARAP1_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 212 | 0.0000000005 | 67.4 | 31 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProtKB.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0051491; P:positive regulation of filopodium assembly; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051270; P:regulation of cellular component movement; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 128 | Q9H0H5 | 632 | RGAP1_HUMAN Rac GTPase-activating protein 1 O... | 203 | 0.0000000008 | 66.2 | 27 | 50 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.::GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; IMP:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0007018; P:microtubule-based movement; TAS:Reactome.::GO:0007405; P:neuroblast proliferation; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007283; P:spermatogenesis; IEP:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; IDA:UniProtKB.::GO:0008272; P:sulfate transport; IDA:UniProtKB. | 129 | P98171 | 946 | RHG04_HUMAN Rho GTPase-activating protein 4 O... | 222 | 0.0000000009 | 66.6 | 23 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; TAS:ProtInc.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 130 | Q4LDD4 | 1452 | ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 203 | 0.000000001 | 66.2 | 30 | 47 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007184; P:SMAD protein import into nucleus; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 131 | Q9WVM1 | 628 | RGAP1_MOUSE Rac GTPase-activating protein 1 O... | 247 | 0.000000001 | 65.5 | 24 | 45 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB. | | | | | | | | | | GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; ISS:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; ISS:UniProtKB.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007405; P:neuroblast proliferation; IEP:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 132 | Q9HF75 | 2071 | BEM2_ASHGO GTPase-activating protein BEM2 OS=... | 192 | 0.000000002 | 65.9 | 26 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 133 | Q54MV3 | 906 | GACJ_DICDI Rho GTPase-activating protein gacJ... | 223 | 0.000000003 | 65.1 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 134 | Q54PG5 | 399 | GACC_DICDI Rho GTPase-activating protein gacC... | 214 | 0.000000003 | 63.9 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 135 | Q54FF4 | 734 | GACL_DICDI Rho GTPase-activating protein gacL... | 341 | 0.000000004 | 64.3 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 136 | G5E5X0 | 674 | LIMD1_BOVIN LIM domain-containing protein 1 O... | 120 | 0.000000006 | 63.9 | 29 | 47 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0016310; P:phosphorylation; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 137 | Q54NL0 | 1009 | GACT_DICDI Rho GTPase-activating protein gacT... | 199 | 0.000000009 | 63.2 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase. | 138 | Q9Y3L3 | 701 | 3BP1_HUMAN SH3 domain-binding protein 1 OS=Ho... | 201 | 0.00000001 | 63.2 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 139 | Q9DBZ9 | 737 | SYDE1_MOUSE Rho GTPase-activating protein SYD... | 234 | 0.00000001 | 63.2 | 25 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 140 | Q9UGP4 | 676 | LIMD1_HUMAN LIM domain-containing protein 1 O... | 120 | 0.00000001 | 62.4 | 29 | 47 | GO:0000932; C:cytoplasmic mRNA processing body; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0016442; C:RNA-induced silencing complex; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0035195; P:gene silencing by miRNA; IMP:MGI.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0016310; P:phosphorylation; IDA:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 141 | Q9VDS5 | 740 | RG92B_DROME Rho GTPase-activating protein 92B... | 233 | 0.00000002 | 62.4 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 142 | A8WRJ2 | 752 | RRC1_CAEBR GTPase-activating protein rrc-1 OS... | 109 | 0.00000002 | 62 | 29 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 143 | Q5R685 | 724 | P85A_PONAB Phosphatidylinositol 3-kinase regu... | 175 | 0.00000002 | 62 | 29 | 43 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 144 | B5DEH0 | 663 | LIMD1_RAT LIM domain-containing protein 1 OS=... | 120 | 0.00000002 | 62 | 29 | 47 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0016310; P:phosphorylation; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 145 | Q54QF4 | 909 | MGP4_DICDI Mental retardation GTPase activati... | 207 | 0.00000004 | 61.2 | 24 | 44 | GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 146 | Q9QXD8 | 668 | LIMD1_MOUSE LIM domain-containing protein 1 O... | 120 | 0.00000004 | 60.8 | 29 | 47 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0002076; P:osteoblast development; IMP:UniProtKB.::GO:0016310; P:phosphorylation; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 147 | Q54XT6 | 783 | GACR_DICDI Rho GTPase-activating protein gacR... | 199 | 0.00000007 | 60.5 | 24 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 148 | Q6ZW31 | 735 | SYDE1_HUMAN Rho GTPase-activating protein SYD... | 216 | 0.00000008 | 60.1 | 25 | 44 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 149 | Q8N392 | 663 | RHG18_HUMAN Rho GTPase-activating protein 18 ... | 180 | 0.0000001 | 59.7 | 26 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 150 | P27986 | 724 | P85A_HUMAN Phosphatidylinositol 3-kinase regu... | 175 | 0.0000001 | 59.7 | 29 | 43 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.::GO:0043559; F:insulin binding; IDA:UniProtKB.::GO:0005158; F:insulin receptor binding; IPI:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.::GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.::GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IPI:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IPI:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IDA:BHF-UCL.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 151 | Q8K2H3 | 851 | FA13B_MOUSE Protein FAM13B OS=Mus musculus (M... | 200 | 0.0000002 | 58.9 | 24 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. |
