Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR368W
Length:
312
Number of sequences:
5887
Description:
YDR368W YPR1 SGDID:S000002776, Chr IV from 1213904-1214842, Genome Release 64-1-1, Verified ORF, "NADPH-dependent aldo-keto reductase, reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q12458    312   YPR1_YEAST Putative reductase 1 OS=Saccharomy...3120     642     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:SGD.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.::GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; IDA:SGD.
GO:0019568; P:arabinose catabolic process; IDA:SGD.::GO:0042843; P:D-xylose catabolic process; IDA:SGD.
2P14065    312   GCY_YEAST Protein GCY OS=Saccharomyces cerevi...3123e-151     434     65     80GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:SGD.::GO:0003729; F:mRNA binding; IDA:SGD.
GO:0019568; P:arabinose catabolic process; IDA:SGD.::GO:0042843; P:D-xylose catabolic process; IDA:SGD.
3P27800    323   ALDX_SPOSA Aldehyde reductase 1 OS=Sporobolom...2951e-72     233     44     62GO:0005623; C:cell; IDA:UniProtKB.
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:UniProtKB.
4A0QV10    275   Y2408_MYCS2 Uncharacterized oxidoreductase MS...2941e-71     229     43     59
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
5Q9JII6    325   AK1A1_MOUSE Alcohol dehydrogenase [NADP(+)] O...3034e-68     222     40     60GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI.::GO:0047939; F:L-glucuronate reductase activity; IDA:MGI.
GO:0046185; P:aldehyde catabolic process; IDA:MGI.::GO:0042840; P:D-glucuronate catabolic process; IDA:MGI.::GO:0019853; P:L-ascorbic acid biosynthetic process; IDA:MGI.
6Q10494    321   YDG7_SCHPO Uncharacterized oxidoreductase C26...2911e-67     220     45     62GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; ISS:PomBase.
GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase.
7P51635    325   AK1A1_RAT Alcohol dehydrogenase [NADP(+)] OS=...3033e-67     219     39     60
8P82125    301   AKCL2_PIG 1,5-anhydro-D-fructose reductase OS...3014e-67     218     41     58
GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC.
9Q5R5D5    325   AK1A1_PONAB Alcohol dehydrogenase [NADP(+)] O...3032e-66     217     39     60
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
10Q6AZW2    324   A1A1A_DANRE Alcohol dehydrogenase [NADP(+)] A...3025e-66     216     40     58
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
11P14550    325   AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] O...3036e-66     216     39     60
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.
GO:0006006; P:glucose metabolic process; TAS:ProtInc.
12Q95JH6    323   AK1C1_MACFU Aldo-keto reductase family 1 memb...3101e-65     215     43     57GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB.
GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
13Q3ZCJ2    325   AK1A1_BOVIN Alcohol dehydrogenase [NADP(+)] O...3033e-65     214     39     58
14Q95JH7    323   AK1C1_MACFA Aldo-keto reductase family 1 memb...3104e-65     214     42     57GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB.
GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
15Q46857    275   DKGA_ECOLI 2,5-diketo-D-gluconic acid reducta...2858e-65     211     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IDA:EcoCyc.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0009438; P:methylglyoxal metabolic process; EXP:EcoCyc.
16O60218    316   AK1BA_HUMAN Aldo-keto reductase family 1 memb...2985e-64     211     42     58GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:ProtInc.
17Q5REQ0    323   AK1C1_PONAB Aldo-keto reductase family 1 memb...3227e-64     211     40     57GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB.
GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
18Q8XBT6    275   DKGA_ECO57 2,5-diketo-D-gluconic acid reducta...2851e-63     209     39     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.
19P50578    325   AK1A1_PIG Alcohol dehydrogenase [NADP(+)] OS=...3032e-63     209     39     58
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
20Q0PGJ6    315   AKRC9_ARATH Aldo-keto reductase family 4 memb...3043e-63     209     41     58GO:0009507; C:chloroplast; IDA:TAIR.
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB.
GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB.
21P80508    323   PE2R_RABIT Prostaglandin-E(2) 9-reductase OS=...3013e-63     209     43     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC.
GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW.
22O42888    325   YBN4_SCHPO Uncharacterized oxidoreductase C8E...3166e-63     208     39     58GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004033; F:aldo-keto reductase (NADP) activity; ISS:PomBase.
GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase.
23P17516    323   AK1C4_HUMAN Aldo-keto reductase family 1 memb...3027e-63     208     40     59GO:0005829; C:cytosol; TAS:Reactome.
GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:ProtInc.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0015125; F:bile acid transmembrane transporter activity; TAS:ProtInc.::GO:0047743; F:chlordecone reductase activity; IEA:EC.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.
GO:0008209; P:androgen metabolic process; TAS:ProtInc.::GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.
24A1UEC5    283   Y1984_MYCSK Uncharacterized oxidoreductase Mk...2968e-63     206     41     56
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
25Q1BAN7    283   Y1938_MYCSS Uncharacterized oxidoreductase Mm...2968e-63     206     41     56
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
26P52895    323   AK1C2_HUMAN Aldo-keto reductase family 1 memb...3049e-63     207     41     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0034694; P:response to prostaglandin stimulus; IDA:UniProtKB.
27A1UEC6    276   Y1985_MYCSK Uncharacterized oxidoreductase Mk...2841e-62     206     42     58
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
28A3PXT0    276   Y1919_MYCSJ Uncharacterized oxidoreductase Mj...2841e-62     206     42     58
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
29Q04828    323   AK1C1_HUMAN Aldo-keto reductase family 1 memb...3042e-62     207     41     58GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IDA:UniProtKB.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0015721; P:bile acid and bile salt transport; TAS:UniProtKB.::GO:0008206; P:bile acid metabolic process; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0042632; P:cholesterol homeostasis; TAS:UniProtKB.::GO:0030299; P:intestinal cholesterol absorption; TAS:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0046683; P:response to organophosphorus; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; NAS:UniProtKB.
30P52898    323   DDBX_BOVIN Dihydrodiol dehydrogenase 3 OS=Bos...3022e-62     207     43     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
31P51652    323   AKC1H_RAT Aldo-keto reductase family 1 member...3033e-62     206     40     58GO:0005829; C:cytosol; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI.
GO:0050810; P:regulation of steroid biosynthetic process; IDA:RGD.
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