Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR364C
Length:
455
Number of sequences:
5887
Description:
YDR364C CDC40 SGDID:S000002772, Chr IV from 1204210-1202843, Genome Release 64-1-1, reverse complement, Verified ORF, "Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression; required for DNA synthesis during mitosis and meiosis; has WD repeats"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40968    455   PRP17_YEAST Pre-mRNA-processing factor 17 OS=...4550     946     100     100GO:0005681; C:spliceosomal complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000350; P:generation of catalytic spliceosome for second transesterification step; IMP:SGD.::GO:0000389; P:nuclear mRNA 3'-splice site recognition; IGI:SGD.::GO:0000348; P:nuclear mRNA branch site recognition; IGI:SGD.
2O43071    558   PRP17_SCHPO Pre-mRNA-processing factor 17 OS=...4379e-95     303     38     58GO:0005681; C:spliceosomal complex; ISS:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
3Q9DC48    579   PRP17_MOUSE Pre-mRNA-processing factor 17 OS=...3917e-87     283     38     57GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
4O60508    579   PRP17_HUMAN Pre-mRNA-processing factor 17 OS=...3912e-86     282     38     57GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:Reactome.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
5E9Q349    535   WDR25_MOUSE WD repeat-containing protein 25 O...2753e-22     102     24     48
6A8X8C6    368   TG125_CAEBR WD repeat-containing protein tag-...3027e-21     97.1     26     46
7Q64LD2    544   WDR25_HUMAN WD repeat-containing protein 25 O...2758e-21     98.6     23     47
8Q8JZX3    405   POC1A_MOUSE POC1 centriolar protein homolog A...2685e-20     95.1     26     46GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.
9Q9D7H2    328   WDR5B_MOUSE WD repeat-containing protein 5B O...3062e-17     86.3     25     44
10Q5M786    334   WDR5_XENTR WD repeat-containing protein 5 OS=...3073e-17     85.9     25     44GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q4V8C4    328   WDR5B_RAT WD repeat-containing protein 5B OS=...3064e-17     85.5     25     44
12Q86VZ2    330   WDR5B_HUMAN WD repeat-containing protein 5B O...2953e-16     82.8     25     44
13Q23256    501   YH92_CAEEL Uncharacterized WD repeat-containi...3010.0000000000001     76.3     25     43
14Q4R8H1    569   TBL1X_MACFA F-box-like/WD repeat-containing p...2900.0000000000002     75.9     27     43GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15P93107    606   PF20_CHLRE Flagellar WD repeat-containing pro...2870.0000000000005     74.7     24     43GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.
16O60907    577   TBL1X_HUMAN F-box-like/WD repeat-containing p...2900.0000000000007     73.9     26     43GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17P38011    319   GBLP_YEAST Guanine nucleotide-binding protein...2660.000000000006     70.1     25     44GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
GO:0001965; F:G-protein alpha-subunit binding; IPI:SGD.::GO:0005092; F:GDP-dissociation inhibitor activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IMP:SGD.
GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:SGD.::GO:0010255; P:glucose mediated signaling pathway; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0017148; P:negative regulation of translation; IMP:SGD.
18B6GZD3    464   LIS12_PENCW Nuclear distribution protein nudF...3060.00000000001     69.7     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
19Q7ZUV2    694   KTNB1_DANRE Katanin p80 WD40-containing subun...1710.00000000002     70.1     27     50GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
20Q9BQ87    522   TBL1Y_HUMAN F-box-like/WD repeat-containing p...2930.00000000003     68.9     25     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q8W1K8    370   MUT11_CHLRE Protein Mut11 OS=Chlamydomonas re...2180.00000000006     67.4     23     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
22Q6GPU3    711   DTLB_XENLA Denticleless protein homolog B OS=...3150.0000000002     66.2     23     41GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
23Q4V837    710   DTLA_XENLA Denticleless protein homolog A OS=...3150.0000000003     66.2     23     42GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
24Q9C1X0    297   YN55_SCHPO Uncharacterized WD repeat-containi...3120.0000000003     64.7     20     36GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
25Q10051    492   PRP19_CAEEL Pre-mRNA-processing factor 19 hom...2790.0000000004     65.5     22     42GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
26Q93847    395   YZLL_CAEEL Uncharacterized WD repeat-containi...2160.0000000005     64.7     29     44
27Q24371    769   L2DTL_DROME Protein lethal(2)denticleless OS=...2490.0000000005     65.5     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
28O76071    339   CIAO1_HUMAN Probable cytosolic iron-sulfur pr...1840.0000000007     63.9     26     46GO:0071817; C:MMXD complex; IDA:UniProtKB.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; IGI:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
29Q32PJ6    339   CIAO1_BOVIN Probable cytosolic iron-sulfur pr...1840.0000000009     63.5     26     46GO:0071817; C:MMXD complex; ISS:UniProtKB.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
30Q39190    479   PRL2_ARATH Protein pleiotropic regulator PRL2...2690.000000001     63.9     27     42GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.
GO:0005515; F:protein binding; IPI:TAIR.
31P25635    923   PWP2_YEAST Periodic tryptophan protein 2 OS=S...2970.000000001     64.3     23     40GO:0005737; C:cytoplasm; IDA:SGD.::GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030515; F:snoRNA binding; IPI:SGD.
GO:0000910; P:cytokinesis; IMP:SGD.::GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.
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