Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR353W
Length:
319
Number of sequences:
5887
Description:
YDR353W TRR1 SGDID:S000002761, Chr IV from 1183299-1184258, Genome Release 64-1-1, Verified ORF, "Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391Q7A3W1    343   FENR_STAAN Ferredoxin--NADP reductase OS=Stap...1701     34.7     20     45
GO:0004324; F:ferredoxin-NADP+ reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
392P92947    493   MDARP_ARATH Monodehydroascorbate reductase, c...2081     34.7     26     38GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0010319; C:stromule; IDA:TAIR.
GO:0005524; F:ATP binding; IDA:TAIR.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016656; F:monodehydroascorbate reductase (NADH) activity; IEA:EC.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.
393A0JX88    892   SYA_ARTS2 Alanine--tRNA ligase OS=Arthrobacte...1251.1     35     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004813; F:alanine-tRNA ligase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro.
394Q86VQ6    682   TRXR3_HUMAN Thioredoxin reductase 3 OS=Homo s...1971.1     34.7     25     41GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; NAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
395P42770    565   GSHRP_ARATH Glutathione reductase, chloroplas...1961.1     34.7     28     43GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.
GO:0005524; F:ATP binding; IDA:TAIR.::GO:0005507; F:copper ion binding; IDA:TAIR.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
396P48639    449   GSHR_BURCE Glutathione reductase OS=Burkholde...1461.3     34.3     29     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
397Q28943    1025   DPYD_PIG Dihydropyrimidine dehydrogenase [NAD...3071.5     34.3     22     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
398P23189    451   GSHR_PSEAE Glutathione reductase OS=12228). G...1961.5     34.3     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
399O62768    499   TRXR1_BOVIN Thioredoxin reductase 1, cytoplas...2131.6     34.3     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
400Q97ZY5    267   RUBPS_SULSO Putative ribose 1,5-bisphosphate ...331.7     33.9     42     73
GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0055114; P:oxidation-reduction process; IEA:InterPro.::GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
401P18925    477   DLDH_AZOVI Dihydrolipoyl dehydrogenase OS=Azo...1961.7     33.9     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
402C3NGI6    267   RUBPS_SULIN Putative ribose 1,5-bisphosphate ...331.7     33.5     42     73
GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0055114; P:oxidation-reduction process; IEA:InterPro.::GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
403C3N749    267   RUBPS_SULIY Putative ribose 1,5-bisphosphate ...331.8     33.5     42     73
GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0055114; P:oxidation-reduction process; IEA:InterPro.::GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
404C3MQY1    267   RUBPS_SULIL Putative ribose 1,5-bisphosphate ...331.8     33.5     42     73
GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0055114; P:oxidation-reduction process; IEA:InterPro.::GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
405C4KIA7    267   RUBPS_SULIK Putative ribose 1,5-bisphosphate ...331.8     33.5     42     73
GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0055114; P:oxidation-reduction process; IEA:InterPro.::GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
406C3N6N6    267   RUBPS_SULIA Putative ribose 1,5-bisphosphate ...331.8     33.5     42     73
GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0055114; P:oxidation-reduction process; IEA:InterPro.::GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
407P11959    470   DLDH1_GEOSE Dihydrolipoyl dehydrogenase OS=Ge...1941.8     33.9     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
408C3MWW9    267   RUBPS_SULIM Putative ribose 1,5-bisphosphate ...331.8     33.5     42     73
GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0055114; P:oxidation-reduction process; IEA:InterPro.::GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
409Q40977    433   MDAR_PEA Monodehydroascorbate reductase OS=Pi...3151.8     33.9     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016656; F:monodehydroascorbate reductase (NADH) activity; IEA:EC.
410Q5R895    1025   DPYD_PONAB Dihydropyrimidine dehydrogenase [N...3402.2     33.9     23     40GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
411A8GG95    379   NORW_SERP5 Nitric oxide reductase FlRd-NAD(+)...1052.4     33.5     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016731; F:oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor; IEA:InterPro.
412Q9JMH6    613   TRXR1_MOUSE Thioredoxin reductase 1, cytoplas...2132.4     33.5     24     43GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI.
GO:0008283; P:cell proliferation; IMP:MGI.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0001707; P:mesoderm formation; IMP:MGI.
413Q12882    1025   DPYD_HUMAN Dihydropyrimidine dehydrogenase [N...3402.7     33.5     23     40GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0006145; P:purine base catabolic process; IMP:UniProtKB.::GO:0006214; P:thymidine catabolic process; IDA:UniProtKB.::GO:0006210; P:thymine catabolic process; IDA:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; IDA:UniProtKB.
414P80461    557   GSHRP_TOBAC Glutathione reductase, chloroplas...1962.8     33.5     27     43GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
415A1W6V2    354   FENR_ACISJ Ferredoxin--NADP reductase OS=Acid...1442.9     33.1     25     45
GO:0004324; F:ferredoxin-NADP+ reductase activity; IEA:EC.
416Q17745    667   TRXR1_CAEEL Thioredoxin reductase 1 OS=Caenor...2133.4     33.1     28     40GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0015036; F:disulfide oxidoreductase activity; NAS:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
417Q5JGP4    442   CDR_PYRKO Coenzyme A disulfide reductase OS=(...1943.7     33.1     27     42GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050451; F:CoA-disulfide reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IEA:InterPro.
418Q9LFA3    434   MDAR3_ARATH Probable monodehydroascorbate red...903.9     32.7     33     56GO:0048046; C:apoplast; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005782; C:peroxisomal matrix; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016656; F:monodehydroascorbate reductase (NADH) activity; IDA:TAIR.
GO:0042744; P:hydrogen peroxide catabolic process; TAS:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.
419Q9MYY8    499   TRXR1_PIG Thioredoxin reductase 1, cytoplasmi...2133.9     32.7     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
420B9KZS7    309   MDH_THERP Malate dehydrogenase OS=Thermomicro...2394.8     32.3     23     39
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
421Q16881    649   TRXR1_HUMAN Thioredoxin reductase 1, cytoplas...2135.4     32.7     24     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; EXP:Reactome.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.::GO:0007165; P:signal transduction; NAS:ProtInc.::GO:0006810; P:transport; IEA:UniProtKB-KW.
records
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