rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q5R5T1 | 737 | FGD3_PONAB FYVE, RhoGEF and PH domain-contain... | 34 | 0.16 | 38.5 | 44 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 92 | Q7Z142 | 202 | YO15_CAEEL Putative zinc finger protein ZK686... | 34 | 0.2 | 37 | 44 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 93 | Q8BUB4 | 400 | WDFY2_MOUSE WD repeat and FYVE domain-contain... | 93 | 0.2 | 37.7 | 33 | 44 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 94 | Q96P53 | 400 | WDFY2_HUMAN WD repeat and FYVE domain-contain... | 93 | 0.2 | 37.7 | 33 | 44 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 95 | Q5JSP0 | 725 | FGD3_HUMAN FYVE, RhoGEF and PH domain-contain... | 66 | 2 | 35 | 27 | 45 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 96 | Q9NYA4 | 1195 | MTMR4_HUMAN Myotubularin-related protein 4 OS... | 44 | 0.27 | 37.7 | 43 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 97 | Q8IZQ1 | 3526 | WDFY3_HUMAN WD repeat and FYVE domain-contain... | 39 | 0.29 | 37.7 | 41 | 51 | GO:0044444; C:cytoplasmic part; IDA:MGI.::GO:0019898; C:extrinsic to membrane; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 98 | Q7ZXF1 | 1078 | MTMR4_XENLA Myotubularin-related protein 4 OS... | 44 | 0.29 | 37.7 | 43 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 99 | A2QWA2 | 703 | VPS27_ASPNC Vacuolar protein sorting-associat... | 42 | 0.3 | 37.4 | 45 | 50 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 100 | Q6VNB8 | 3508 | WDFY3_MOUSE WD repeat and FYVE domain-contain... | 39 | 0.3 | 37.7 | 41 | 51 | | | | | | | | | | | GO:0003831; F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 101 | Q5BBK9 | 715 | VPS27_EMENI Vacuolar protein sorting-associat... | 42 | 0.32 | 37.4 | 45 | 50 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 102 | Q91XS1 | 1190 | MTMR4_MOUSE Myotubularin-related protein 4 OS... | 44 | 0.34 | 37.4 | 43 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 103 | A1CEK1 | 714 | VPS27_ASPCL Vacuolar protein sorting-associat... | 41 | 0.37 | 37.4 | 46 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 104 | Q4WHN8 | 729 | VPS27_ASPFU Vacuolar protein sorting-associat... | 42 | 0.37 | 37.4 | 45 | 50 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 105 | A1DFP5 | 729 | VPS27_NEOFI Vacuolar protein sorting-associat... | 42 | 0.38 | 37.4 | 45 | 50 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 106 | Q9LIH7 | 345 | ZDHC7_ARATH Probable S-acyltransferase At3g18... | 72 | 0.5 | 36.6 | 35 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 107 | P45167 | 459 | UUP2_HAEIN ABC transporter ATP-binding protei... | 72 | 0.57 | 36.6 | 33 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro. | | | | | | | | | | GO:0006810; P:transport; IEA:UniProtKB-KW. | 108 | Q7Z3T8 | 1539 | ZFY16_HUMAN Zinc finger FYVE domain-containin... | 42 | 0.59 | 36.6 | 40 | 43 | GO:0031901; C:early endosome membrane; TAS:Reactome. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IMP:UniProtKB. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0016197; P:endosome transport; IMP:UniProtKB.::GO:0006622; P:protein targeting to lysosome; IMP:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:0016050; P:vesicle organization; NAS:UniProtKB. | 109 | Q80U44 | 1528 | ZFY16_MOUSE Zinc finger FYVE domain-containin... | 42 | 0.68 | 36.6 | 40 | 43 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 110 | Q9Y4B5 | 1905 | CC165_HUMAN Coiled-coil domain-containing pro... | 162 | 0.7 | 36.6 | 27 | 45 | | | | | | | | | | | | | | | | | | | | | | 111 | O95405 | 1425 | ZFYV9_HUMAN Zinc finger FYVE domain-containin... | 44 | 0.72 | 36.6 | 34 | 39 | GO:0031901; C:early endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0007183; P:SMAD protein complex assembly; IDA:UniProtKB.::GO:0007184; P:SMAD protein import into nucleus; IMP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB. | 112 | Q22712 | 1006 | MTMR3_CAEEL Myotublarin-related protein 3 OS=... | 36 | 0.77 | 36.2 | 44 | 58 | | | | | | | | | | | GO:0016312; F:inositol bisphosphate phosphatase activity; IDA:WormBase.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0034594; F:phosphatidylinositol trisphosphate phosphatase activity; IDA:WormBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:WormBase.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0045807; P:positive regulation of endocytosis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase. | 113 | Q7QAJ2 | 1161 | LST2_ANOGA Lateral signaling target protein 2... | 34 | 0.82 | 36.2 | 41 | 47 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 114 | O88842 | 733 | FGD3_MOUSE FYVE, RhoGEF and PH domain-contain... | 112 | 0.89 | 36.2 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IDA:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 115 | Q7ZUV1 | 247 | PKHF2_DANRE Pleckstrin homology domain-contai... | 89 | 0.91 | 35.4 | 28 | 38 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 116 | A4QTV1 | 713 | VPS27_MAGO7 Vacuolar protein sorting-associat... | 90 | 1.7 | 35 | 28 | 39 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0043581; P:mycelium development; IEP:PAMGO_MGG. | 117 | Q57242 | 647 | UUP1_HAEIN ABC transporter ATP-binding protei... | 72 | 2 | 34.7 | 32 | 57 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro. | | | | | | | | | | GO:0006810; P:transport; IEA:UniProtKB-KW. | 118 | Q18964 | 415 | WDFY2_CAEEL WD repeat and FYVE domain-contain... | 51 | 2.2 | 34.7 | 33 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:WormBase.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:WormBase. | 119 | A8XXC7 | 417 | WDFY2_CAEBR WD repeat and FYVE domain-contain... | 51 | 2.5 | 34.3 | 33 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 120 | Q86C65 | 2380 | TOR_DICDI Target of rapamycin OS=Dictyosteliu... | 110 | 3.5 | 34.3 | 27 | 44 | GO:0031932; C:TORC2 complex; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. | 121 | O15015 | 1829 | ZN646_HUMAN Zinc finger protein 646 OS=Homo s... | 162 | 4.1 | 33.9 | 23 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |