Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR323C
Length:
515
Number of sequences:
5887
Description:
YDR323C PEP7 SGDID:S000002731, Chr IV from 1114027-1112480, Genome Release 64-1-1, reverse complement, Verified ORF, "Multivalent adaptor protein that facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q5RFL4    789   ZFYV1_PONAB Zinc finger FYVE domain-containin...800.022     41.2     33     46GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
62Q9Y7M3    293   YNT3_SCHPO FYVE-type zinc finger-containing p...360.009     42     47     58GO:0000324; C:fungal-type vacuole; IDA:PomBase.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
63Q9BQ24    234   ZFY21_HUMAN Zinc finger FYVE domain-containin...470.009     41.6     40     49GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
64B4K982    1051   LST2_DROMO Lateral signaling target protein 2...810.009     42.4     32     42GO:0016020; C:membrane; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:InterPro.
65B4M140    1052   LST2_DROVI Lateral signaling target protein 2...810.01     42.4     32     42
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
66P34756    2278   FAB1_YEAST 1-phosphatidylinositol 3-phosphate...402.4     34.7     35     58GO:0010008; C:endosome membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0070772; C:PAS complex; IDA:SGD.
GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.
GO:0044267; P:cellular protein metabolic process; IEA:InterPro.
67Q9BQS8    1478   FYCO1_HUMAN FYVE and coiled-coil domain-conta...760.012     42.4     29     43GO:0005776; C:autophagic vacuole; IDA:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0072383; P:plus-end-directed vesicle transport along microtubule; IMP:UniProtKB.
68B4NFJ7    993   LST2_DROWI Lateral signaling target protein 2...810.015     42     30     41
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
69P52734    960   FGD1_MOUSE FYVE, RhoGEF and PH domain-contain...410.017     41.6     46     61GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
70Q8VCM3    234   ZFY21_MOUSE Zinc finger FYVE domain-containin...470.018     40.4     38     49GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
71P98174    961   FGD1_HUMAN FYVE, RhoGEF and PH domain-contain...410.019     41.6     46     61GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
72Q755J9    604   VPS27_ASHGO Vacuolar protein sorting-associat...360.019     41.2     47     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
73D3ZVP7    234   ZFY21_RAT Zinc finger FYVE domain-containing ...470.02     40.4     38     49GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
74B4G2G5    1009   LST2_DROPE Lateral signaling target protein 2...810.021     41.2     32     41
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
75A8QCE4    619   LST2_BRUMA Lateral signaling target protein 2...490.022     41.2     37     47
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
76Q96T51    708   RUFY1_HUMAN RUN and FYVE domain-containing pr...470.025     41.2     38     51GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
77B0WAQ0    907   LST2_CULQU Lateral signaling target protein 2...820.026     40.8     29     40
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
78Q17AN2    912   LST2_AEDAE Lateral signaling target protein 2...810.027     40.8     30     41
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
79Q8BIJ7    712   RUFY1_MOUSE RUN and FYVE domain-containing pr...470.027     40.8     38     51GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008565; F:protein transporter activity; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IDA:MGI.
80Q8K296    1196   MTMR3_MOUSE Myotubularin-related protein 3 OS...450.035     40.8     40     49
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.
81Q5PQT2    1194   MTMR3_RAT Myotubularin-related protein 3 OS=R...450.036     40.8     40     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.
82Q13615    1198   MTMR3_HUMAN Myotubularin-related protein 3 OS...450.038     40.4     40     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.
83O13821    610   VPS27_SCHPO Vacuolar protein sorting-associat...610.044     40     41     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005628; C:prospore membrane; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; ISS:PomBase.::GO:0043130; F:ubiquitin binding; IMP:PomBase.
GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0006897; P:endocytosis; IMP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0045053; P:protein retention in Golgi apparatus; ISS:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
84Q5ZLY5    249   PKHF2_CHICK Pleckstrin homology domain-contai...890.063     38.9     29     40
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
85Q91WB4    249   PKHF2_MOUSE Pleckstrin homology domain-contai...890.069     38.9     29     40
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
86Q8VDC1    1437   FYCO1_MOUSE FYVE and coiled-coil domain-conta...564.1     33.9     30     43GO:0005776; C:autophagic vacuole; ISS:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0072383; P:plus-end-directed vesicle transport along microtubule; ISS:UniProtKB.
87Q9H8W4    249   PKHF2_HUMAN Pleckstrin homology domain-contai...890.086     38.5     29     40GO:0030133; C:transport vesicle; IDA:LIFEdb.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
88Q960X8    760   HRS_DROME Hepatocyte growth factor-regulated ...890.089     39.3     30     38GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; NAS:FlyBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0006897; P:endocytosis; IMP:FlyBase.::GO:0016197; P:endosome transport; TAS:FlyBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; NAS:FlyBase.::GO:0045752; P:positive regulation of Toll signaling pathway; IMP:FlyBase.::GO:0016082; P:synaptic vesicle priming; NAS:FlyBase.::GO:0008293; P:torso signaling pathway; NAS:FlyBase.::GO:0016050; P:vesicle organization; NAS:FlyBase.
89Q0U4Z8    720   VPS27_PHANO Vacuolar protein sorting-associat...870.13     38.5     31     41GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
90Q80UZ0    1219   FGD5_MOUSE FYVE, RhoGEF and PH domain-contain...360.14     38.5     44     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
91Q5R5T1    737   FGD3_PONAB FYVE, RhoGEF and PH domain-contain...340.16     38.5     44     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
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