rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9JJ50 | 776 | HGS_RAT Hepatocyte growth factor-regulated ty... | 69 | 0.000002 | 52.8 | 32 | 49 | GO:0005829; C:cytosol; IDA:RGD.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.::GO:0030141; C:secretory granule; IDA:RGD. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; NAS:RGD. | | | | | | | | | | GO:0008333; P:endosome to lysosome transport; IMP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 32 | B0WAQ0 | 907 | LST2_CULQU Lateral signaling target protein 2... | 72 | 0.000002 | 52.8 | 35 | 46 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 33 | Q6ZV73 | 1430 | FGD6_HUMAN FYVE, RhoGEF and PH domain-contain... | 78 | 0.000002 | 52.8 | 31 | 45 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 34 | Q6ZPK7 | 905 | LST2_MOUSE Lateral signaling target protein 2... | 74 | 0.000002 | 52.8 | 34 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB. | 35 | Q05B78 | 254 | ZFY21_BOVIN Zinc finger FYVE domain-containin... | 46 | 0.000002 | 51.6 | 46 | 54 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 36 | Q5R5R4 | 606 | RUFY2_PONAB RUN and FYVE domain-containing pr... | 40 | 0.000002 | 52 | 50 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 37 | Q7ZXF1 | 1078 | MTMR4_XENLA Myotubularin-related protein 4 OS... | 77 | 0.000003 | 52.4 | 32 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 38 | Q8WXA3 | 655 | RUFY2_HUMAN RUN and FYVE domain-containing pr... | 77 | 0.000003 | 52 | 35 | 49 | GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 39 | Q9HCC9 | 887 | LST2_HUMAN Lateral signaling target protein 2... | 74 | 0.000003 | 52.4 | 34 | 45 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IMP:UniProtKB. | 40 | B3MT31 | 985 | LST2_DROAN Lateral signaling target protein 2... | 71 | 0.000003 | 52.4 | 37 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 41 | Q5ZLY5 | 249 | PKHF2_CHICK Pleckstrin homology domain-contai... | 96 | 0.000003 | 51.2 | 34 | 46 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 42 | Q0V8S0 | 777 | HGS_BOVIN Hepatocyte growth factor-regulated ... | 69 | 0.000003 | 52 | 30 | 49 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 43 | Q0P4S0 | 951 | LST2_XENTR Lateral signaling target protein 2... | 74 | 0.000003 | 52 | 34 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB. | 44 | B4M140 | 1052 | LST2_DROVI Lateral signaling target protein 2... | 71 | 0.000004 | 52 | 37 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 45 | B4K982 | 1051 | LST2_DROMO Lateral signaling target protein 2... | 71 | 0.000004 | 51.6 | 37 | 45 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:InterPro. | 46 | Q54TC3 | 585 | SLOB1_DICDI Probable inactive serine/threonin... | 43 | 0.000005 | 51.2 | 44 | 63 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | | 47 | Q17AN2 | 912 | LST2_AEDAE Lateral signaling target protein 2... | 72 | 0.000005 | 51.2 | 35 | 46 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 48 | Q91WB4 | 249 | PKHF2_MOUSE Pleckstrin homology domain-contai... | 100 | 0.000006 | 50.1 | 34 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 49 | B4PRU6 | 984 | LST2_DROYA Lateral signaling target protein 2... | 86 | 0.000006 | 51.2 | 31 | 42 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 50 | B3P851 | 981 | LST2_DROER Lateral signaling target protein 2... | 86 | 0.000006 | 51.2 | 31 | 42 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 51 | Q69ZL1 | 1399 | FGD6_MOUSE FYVE, RhoGEF and PH domain-contain... | 80 | 0.000007 | 51.2 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 52 | B4JHI7 | 1115 | LST2_DROGR Lateral signaling target protein 2... | 71 | 0.000007 | 50.8 | 35 | 46 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 53 | Q91XS1 | 1190 | MTMR4_MOUSE Myotubularin-related protein 4 OS... | 77 | 0.000007 | 50.8 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 54 | Q9H8W4 | 249 | PKHF2_HUMAN Pleckstrin homology domain-contai... | 77 | 0.000007 | 50.1 | 39 | 49 | GO:0030133; C:transport vesicle; IDA:LIFEdb. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 55 | Q8R4C2 | 606 | RUFY2_MOUSE RUN and FYVE domain-containing pr... | 77 | 0.000007 | 50.8 | 34 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 56 | Q9VB70 | 989 | LST2_DROME Lateral signaling target protein 2... | 71 | 0.000007 | 50.8 | 35 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 57 | Q9BQ24 | 234 | ZFY21_HUMAN Zinc finger FYVE domain-containin... | 38 | 0.000008 | 49.7 | 50 | 61 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 58 | B4G2G5 | 1009 | LST2_DROPE Lateral signaling target protein 2... | 71 | 0.000009 | 50.8 | 35 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 59 | B4IC49 | 975 | LST2_DROSE Lateral signaling target protein 2... | 71 | 0.000009 | 50.8 | 35 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 60 | B4NFJ7 | 993 | LST2_DROWI Lateral signaling target protein 2... | 71 | 0.00001 | 50.1 | 35 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 61 | Q9Y2I7 | 2098 | FYV1_HUMAN 1-phosphatidylinositol 3-phosphate... | 37 | 0.00001 | 50.4 | 49 | 59 | GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC. | | | | | | | | | | GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IEA:EC.::GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; TAS:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0044267; P:cellular protein metabolic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034504; P:protein localization to nucleus; IMP:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB. |