Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR313C
Length:
286
Number of sequences:
5887
Description:
YDR313C PIB1 SGDID:S000002721, Chr IV from 1090079-1089219, Genome Release 64-1-1, reverse complement, Verified ORF, "RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q9JJ50    776   HGS_RAT Hepatocyte growth factor-regulated ty...690.000002     52.8     32     49GO:0005829; C:cytosol; IDA:RGD.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.::GO:0030141; C:secretory granule; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; NAS:RGD.
GO:0008333; P:endosome to lysosome transport; IMP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
32B0WAQ0    907   LST2_CULQU Lateral signaling target protein 2...720.000002     52.8     35     46
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
33Q6ZV73    1430   FGD6_HUMAN FYVE, RhoGEF and PH domain-contain...780.000002     52.8     31     45GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
34Q6ZPK7    905   LST2_MOUSE Lateral signaling target protein 2...740.000002     52.8     34     45GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
35Q05B78    254   ZFY21_BOVIN Zinc finger FYVE domain-containin...460.000002     51.6     46     54GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
36Q5R5R4    606   RUFY2_PONAB RUN and FYVE domain-containing pr...400.000002     52     50     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
37Q7ZXF1    1078   MTMR4_XENLA Myotubularin-related protein 4 OS...770.000003     52.4     32     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
38Q8WXA3    655   RUFY2_HUMAN RUN and FYVE domain-containing pr...770.000003     52     35     49GO:0005634; C:nucleus; IDA:HPA.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
39Q9HCC9    887   LST2_HUMAN Lateral signaling target protein 2...740.000003     52.4     34     45GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IMP:UniProtKB.
40B3MT31    985   LST2_DROAN Lateral signaling target protein 2...710.000003     52.4     37     45
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
41Q5ZLY5    249   PKHF2_CHICK Pleckstrin homology domain-contai...960.000003     51.2     34     46
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
42Q0V8S0    777   HGS_BOVIN Hepatocyte growth factor-regulated ...690.000003     52     30     49GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
43Q0P4S0    951   LST2_XENTR Lateral signaling target protein 2...740.000003     52     34     45GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
44B4M140    1052   LST2_DROVI Lateral signaling target protein 2...710.000004     52     37     45
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
45B4K982    1051   LST2_DROMO Lateral signaling target protein 2...710.000004     51.6     37     45GO:0016020; C:membrane; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:InterPro.
46Q54TC3    585   SLOB1_DICDI Probable inactive serine/threonin...430.000005     51.2     44     63
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
47Q17AN2    912   LST2_AEDAE Lateral signaling target protein 2...720.000005     51.2     35     46
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
48Q91WB4    249   PKHF2_MOUSE Pleckstrin homology domain-contai...1000.000006     50.1     34     45
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
49B4PRU6    984   LST2_DROYA Lateral signaling target protein 2...860.000006     51.2     31     42
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
50B3P851    981   LST2_DROER Lateral signaling target protein 2...860.000006     51.2     31     42
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
51Q69ZL1    1399   FGD6_MOUSE FYVE, RhoGEF and PH domain-contain...800.000007     51.2     31     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
52B4JHI7    1115   LST2_DROGR Lateral signaling target protein 2...710.000007     50.8     35     46
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
53Q91XS1    1190   MTMR4_MOUSE Myotubularin-related protein 4 OS...770.000007     50.8     31     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
54Q9H8W4    249   PKHF2_HUMAN Pleckstrin homology domain-contai...770.000007     50.1     39     49GO:0030133; C:transport vesicle; IDA:LIFEdb.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
55Q8R4C2    606   RUFY2_MOUSE RUN and FYVE domain-containing pr...770.000007     50.8     34     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
56Q9VB70    989   LST2_DROME Lateral signaling target protein 2...710.000007     50.8     35     45
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
57Q9BQ24    234   ZFY21_HUMAN Zinc finger FYVE domain-containin...380.000008     49.7     50     61GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
58B4G2G5    1009   LST2_DROPE Lateral signaling target protein 2...710.000009     50.8     35     45
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
59B4IC49    975   LST2_DROSE Lateral signaling target protein 2...710.000009     50.8     35     45
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
60B4NFJ7    993   LST2_DROWI Lateral signaling target protein 2...710.00001     50.1     35     45
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
61Q9Y2I7    2098   FYV1_HUMAN 1-phosphatidylinositol 3-phosphate...370.00001     50.4     49     59GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.
GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IEA:EC.::GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; TAS:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0044267; P:cellular protein metabolic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034504; P:protein localization to nucleus; IMP:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
records
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