rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P47822 | 140 | MED21_YEAST Mediator of RNA polymerase II tra... | 140 | 2e-97 | 283 | 100 | 100 | GO:0070847; C:core mediator complex; IDA:SGD. | | | | | | | | | | GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:SGD.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:SGD.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IMP:SGD. | | | | | | | | | | | 2 | Q6FNK3 | 219 | MED21_CANGA Mediator of RNA polymerase II tra... | 140 | 3e-64 | 201 | 72 | 81 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q6CT76 | 143 | MED21_KLULA Mediator of RNA polymerase II tra... | 137 | 2e-55 | 176 | 65 | 77 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q75EX7 | 142 | MED21_ASHGO Mediator of RNA polymerase II tra... | 138 | 1e-54 | 174 | 62 | 78 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q6BQ63 | 173 | MED21_DEBHA Mediator of RNA polymerase II tra... | 173 | 7e-34 | 122 | 42 | 57 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | A3LS24 | 164 | MED21_PICST Mediator of RNA polymerase II tra... | 163 | 1e-33 | 121 | 44 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q5ACU4 | 178 | MED21_CANAL Mediator of RNA polymerase II tra... | 177 | 2e-29 | 110 | 36 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q6C5U8 | 140 | MED21_YARLI Mediator of RNA polymerase II tra... | 126 | 9e-24 | 95.1 | 45 | 67 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q7S8C2 | 137 | MED21_NEUCR Mediator of RNA polymerase II tra... | 128 | 1e-20 | 86.7 | 39 | 64 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | A1C712 | 189 | MED21_ASPCL Mediator of RNA polymerase II tra... | 178 | 0.000000000004 | 63.9 | 29 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | O94376 | 138 | MED21_SCHPO Mediator of RNA polymerase II tra... | 129 | 0.00000000001 | 62.4 | 32 | 52 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0016592; C:mediator complex; IDA:PomBase. | | | | | | | | | | GO:0001104; F:RNA polymerase II transcription cofactor activity; ISS:PomBase. | | | | | | | | | | | 12 | Q0U499 | 155 | MED21_PHANO Mediator of RNA polymerase II tra... | 160 | 0.00000003 | 52.8 | 31 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q16RX1 | 141 | MED21_AEDAE Mediator of RNA polymerase II tra... | 136 | 0.0000002 | 50.4 | 29 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q2UF93 | 208 | MED21_ASPOR Mediator of RNA polymerase II tra... | 30 | 0.0009 | 41.2 | 57 | 67 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | A2QC41 | 196 | MED21_ASPNC Mediator of RNA polymerase II tra... | 161 | 0.0000003 | 50.4 | 30 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q4X0I5 | 207 | MED21_ASPFU Mediator of RNA polymerase II tra... | 30 | 0.0002 | 42.7 | 57 | 67 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q7ZTI5 | 145 | MED21_DANRE Mediator of RNA polymerase II tra... | 145 | 0.000006 | 46.2 | 28 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q1DXC2 | 192 | MED21_COCIM Mediator of RNA polymerase II tra... | 155 | 0.00002 | 45.8 | 27 | 35 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q2TBU8 | 144 | MED21_BOVIN Mediator of RNA polymerase II tra... | 139 | 0.00005 | 43.5 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q9CQ39 | 144 | MED21_MOUSE Mediator of RNA polymerase II tra... | 139 | 0.0001 | 42.7 | 28 | 45 | GO:0016592; C:mediator complex; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0001824; P:blastocyst development; IMP:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IC:MGI. | 21 | Q4R6N3 | 144 | MED21_MACFA Mediator of RNA polymerase II tra... | 139 | 0.0001 | 42.7 | 28 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q13503 | 144 | MED21_HUMAN Mediator of RNA polymerase II tra... | 141 | 0.0001 | 42.4 | 28 | 48 | GO:0016592; C:mediator complex; IDA:MGI. | | | | | | | | | | GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; IDA:MGI. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI. | 23 | Q5AZQ7 | 203 | MED21_EMENI Mediator of RNA polymerase II tra... | 43 | 0.033 | 36.6 | 42 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | A1DHP1 | 207 | MED21_NEOFI Mediator of RNA polymerase II tra... | 82 | 0.002 | 40.4 | 33 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | Q9W5P1 | 142 | MED21_DROME Mediator of RNA polymerase II tra... | 138 | 0.0003 | 41.6 | 29 | 44 | GO:0016592; C:mediator complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IMP:UniProtKB. | | | | | | | | | | | 26 | Q5RE46 | 144 | MED21_PONAB Mediator of RNA polymerase II tra... | 143 | 0.0005 | 40.8 | 27 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q7PTL0 | 154 | MED21_ANOGA Mediator of RNA polymerase II tra... | 144 | 0.005 | 38.5 | 28 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | A2VCL2 | 907 | CC162_HUMAN Coiled-coil domain-containing pro... | 65 | 0.61 | 33.5 | 28 | 55 | | | | | | | | | | | | | | | | | | | | | | 29 | P72525 | 823 | PARC_STRPN DNA topoisomerase 4 subunit A OS=S... | 70 | 0.98 | 32.7 | 31 | 49 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 30 | P08775 | 1970 | RPB1_MOUSE DNA-directed RNA polymerase II sub... | 121 | 1.1 | 32.7 | 25 | 48 | GO:0005665; C:DNA-directed RNA polymerase II, core complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB. | 31 | P24928 | 1970 | RPB1_HUMAN DNA-directed RNA polymerase II sub... | 121 | 1.1 | 32.7 | 25 | 48 | GO:0005665; C:DNA-directed RNA polymerase II, core complex; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0003899; F:DNA-directed RNA polymerase activity; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006370; P:mRNA capping; TAS:Reactome.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006468; P:protein phosphorylation; IDA:GOC.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.::GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. |