Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR308C
Length:
140
Number of sequences:
5887
Description:
YDR308C SRB7 SGDID:S000002716, Chr IV from 1078449-1078027, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P24928    1970   RPB1_HUMAN DNA-directed RNA polymerase II sub...1211.1     32.7     25     48GO:0005665; C:DNA-directed RNA polymerase II, core complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0003899; F:DNA-directed RNA polymerase activity; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
GO:0006370; P:mRNA capping; TAS:Reactome.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006468; P:protein phosphorylation; IDA:GOC.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.::GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
32C0LU16    139   MED21_ARATH Mediator of RNA polymerase II tra...1061.4     31.6     25     42GO:0016592; C:mediator complex; TAS:UniProtKB.::GO:0043078; C:polar nucleus; IMP:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0050832; P:defense response to fungus; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33Q4V7L5    115   MED9_XENLA Mediator of RNA polymerase II tran...571.7     31.2     32     54GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
34Q80TG1    1036   KANL1_MOUSE KAT8 regulatory NSL complex subun...761.9     32     32     47GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.
35O97681    854   VPP2_BOVIN V-type proton ATPase 116 kDa subun...693.1     31.2     32     55GO:0001669; C:acrosomal vesicle; ISS:AgBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
36P22956    767   RDRP_RCNMV RNA-directed RNA polymerase OS=Red...793.3     31.2     32     48
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.
37P22438    575   SYMM_YEAST Methionine--tRNA ligase, mitochond...493.5     31.2     45     59GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IMP:SGD.
GO:0006431; P:methionyl-tRNA aminoacylation; IMP:SGD.
38Q9Y487    856   VPP2_HUMAN V-type proton ATPase 116 kDa subun...693.7     31.2     30     57GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0033572; P:transferrin transport; TAS:Reactome.
39B8MJJ5    804   EFGM_TALSN Elongation factor G, mitochondrial...833.8     30.8     27     51GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
40P0DG07    819   PARC_STRPQ DNA topoisomerase 4 subunit A OS=S...704.2     30.8     30     46GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
41Q8P1B3    819   PARC_STRP8 DNA topoisomerase 4 subunit A OS=S...704.3     30.8     30     46GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
42Q5XCJ9    819   PARC_STRP6 DNA topoisomerase 4 subunit A OS=S...704.3     30.8     30     46GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
43P0DG06    819   PARC_STRP3 DNA topoisomerase 4 subunit A OS=S...704.3     30.8     30     46GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
44Q9L7Q4    819   PARC_STRP1 DNA topoisomerase 4 subunit A OS=S...704.4     30.8     30     46GO:0005694; C:chromosome; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
GO:0006265; P:DNA topological change; IEA:InterPro.
45Q6BDS2    1440   URFB1_HUMAN UHRF1-binding protein 1 OS=Homo s...356     30.4     37     71
GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0042802; F:identical protein binding; IPI:BHF-UCL.
46Q10168    598   NSP1_SCHPO Nucleoporin nsp1 OS=Schizosaccharo...1076.1     30.4     28     44GO:0031965; C:nuclear membrane; IDA:PomBase.::GO:0005643; C:nuclear pore; IDA:PomBase.
GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0000054; P:ribosomal subunit export from nucleus; ISS:PomBase.
47P14567    1160   DPO3A_SALTY DNA polymerase III subunit alpha ...856.7     30.4     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
48P70388    1312   RAD50_MOUSE DNA repair protein RAD50 OS=Mus m...997.5     30     30     46GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0030870; C:Mre11 complex; IEA:InterPro.::GO:0045120; C:pronucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
49Q8VCS6    142   MED9_MOUSE Mediator of RNA polymerase II tran...579.6     29.3     30     56GO:0016592; C:mediator complex; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
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