Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR295C
Length:
674
Number of sequences:
5887
Description:
YDR295C HDA2 SGDID:S000002703, Chr IV from 1054647-1052623, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex containing an Hda1p homodimer and an Hda2p-Hda3p heterodimer; involved in telomere maintenance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q06629    674   HDA2_YEAST HDA1 complex subunit 2 OS=Saccharo...6740     1379     100     100GO:0070823; C:HDA1 complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003677; F:DNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031047; P:gene silencing by RNA; IMP:SGD.::GO:0010978; P:gene silencing involved in chronological cell aging; IMP:SGD.::GO:0016575; P:histone deacetylation; IDA:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q75EZ7    665   HDA2_ASHGO HDA1 complex subunit 2 OS=Y-1056) ...7057e-114     363     35     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q06623    655   HDA3_YEAST HDA1 complex subunit 3 OS=Saccharo...1640.0000000001     68.6     30     46GO:0070823; C:HDA1 complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003677; F:DNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0031047; P:gene silencing by RNA; IMP:SGD.::GO:0010978; P:gene silencing involved in chronological cell aging; IMP:SGD.::GO:0016575; P:histone deacetylation; IDA:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q758V8    637   HDA3_ASHGO HDA1 complex subunit 3 OS=Y-1056) ...1710.0000005     56.6     26     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q92569    461   P55G_HUMAN Phosphatidylinositol 3-kinase regu...1160.21     38.5     29     52
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:ProtInc.
GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.
6O46404    461   P55G_BOVIN Phosphatidylinositol 3-kinase regu...870.33     37.7     31     51GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro.
7Q63789    461   P55G_RAT Phosphatidylinositol 3-kinase regula...860.44     37.4     30     50
GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IDA:RGD.
8Q64143    461   P55G_MOUSE Phosphatidylinositol 3-kinase regu...860.45     37.4     30     50GO:0005942; C:phosphatidylinositol 3-kinase complex; IPI:MGI.
GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0008286; P:insulin receptor signaling pathway; IDA:MGI.
9Q21313    3672   EPI1_CAEEL Laminin-like protein epi-1 OS=Caen...1800.68     37     25     47GO:0005604; C:basement membrane; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:InterPro.
10E9Q557    2883   DESP_MOUSE Desmoplakin OS=Mus musculus (Mouse...1762     35.4     25     49GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0030057; C:desmosome; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0034332; P:adherens junction organization; IMP:MGI.::GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0043588; P:skin development; IMP:MGI.
11A5GND0    171   ATPF_SYNPW ATP synthase subunit b OS=Synechoc...1412.3     33.9     21     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.::GO:0042651; C:thylakoid membrane; IEA:UniProtKB-SubCell.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
12Q8UUU2    722   P85AA_XENLA Phosphatidylinositol 3-kinase reg...1012.8     35     29     52GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.
GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB.
GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.
13P32399    775   YHGE_BACSU Uncharacterized protein yhgE OS=Ba...2272.8     35     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
14P27986    724   P85A_HUMAN Phosphatidylinositol 3-kinase regu...874     34.3     30     52GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.::GO:0043559; F:insulin binding; IDA:UniProtKB.::GO:0005158; F:insulin receptor binding; IPI:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.::GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.::GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IPI:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IPI:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IDA:BHF-UCL.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
15Q8IYE1    715   CCD13_HUMAN Coiled-coil domain-containing pro...654.1     34.3     34     58
16P24043    3122   LAMA2_HUMAN Laminin subunit alpha-2 OS=Homo s...1834.3     34.7     24     44GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; TAS:ProtInc.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
17Q5R685    724   P85A_PONAB Phosphatidylinositol 3-kinase regu...874.3     34.3     30     52GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
18P15924    2871   DESP_HUMAN Desmoplakin OS=Homo sapiens (Human...1614.5     34.3     24     47GO:0001533; C:cornified envelope; IDA:UniProtKB.::GO:0030057; C:desmosome; IEA:UniProtKB-SubCell.
GO:0030674; F:protein binding, bridging; IDA:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.::GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
19P57599    241   FKBA_BUCAI FKBP-type peptidyl-prolyl cis-tran...1124.6     33.5     29     48
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
20Q0I7R0    173   ATPF_SYNS3 ATP synthase subunit b OS=Synechoc...1415.6     32.7     23     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.::GO:0042651; C:thylakoid membrane; IEA:UniProtKB-SubCell.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
21Q60902    907   EP15R_MOUSE Epidermal growth factor receptor ...1716.6     33.9     23     47GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
22Q0AWF3    812   LON_SYNWW Lon protease OS=Syntrophomonas wolf...1737.3     33.5     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
23Q9UBC2    864   EP15R_HUMAN Epidermal growth factor receptor ...1719.3     33.1     23     46GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
24Q9ULD2    1270   MTUS1_HUMAN Microtubule-associated tumor supp...1769.8     33.1     27     48GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
records
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