Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR294C
Length:
589
Number of sequences:
5887
Description:
YDR294C DPL1 SGDID:S000002702, Chr IV from 1052228-1050459, Genome Release 64-1-1, reverse complement, Verified ORF, "Dihydrosphingosine phosphate lyase, regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs), degrades phosphorylated long chain bases, prefers C16 dihydrosphingosine-l-phosphate as a substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q05567    589   SGPL_YEAST Sphingosine-1-phosphate lyase OS=S...5890     1227     100     100GO:0032541; C:cortical endoplasmic reticulum; IDA:SGD.::GO:0097038; C:perinuclear endoplasmic reticulum; IDA:SGD.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IDA:SGD.
GO:0019722; P:calcium-mediated signaling; IMP:SGD.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0009267; P:cellular response to starvation; IMP:SGD.::GO:0006665; P:sphingolipid metabolic process; IGI:SGD.
2Q8CHN6    568   SGPL1_RAT Sphingosine-1-phosphate lyase 1 OS=...5284e-137     418     42     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0006672; P:ceramide metabolic process; ISS:UniProtKB.
3Q8R0X7    568   SGPL1_MOUSE Sphingosine-1-phosphate lyase 1 O...5281e-136     416     41     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
GO:0008209; P:androgen metabolic process; IMP:MGI.::GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0006672; P:ceramide metabolic process; ISS:UniProtKB.::GO:0008210; P:estrogen metabolic process; IMP:MGI.::GO:0060325; P:face morphogenesis; IMP:MGI.::GO:0010761; P:fibroblast migration; IMP:MGI.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0001822; P:kidney development; IMP:MGI.::GO:0033327; P:Leydig cell differentiation; IMP:MGI.::GO:0001553; P:luteinization; IMP:MGI.::GO:0006807; P:nitrogen compound metabolic process; IMP:MGI.::GO:0060021; P:palate development; IMP:MGI.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI.
4Q9V7Y2    545   SGPL_DROME Sphingosine-1-phosphate lyase OS=D...4954e-135     412     43     61GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:UniProtKB.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; NAS:UniProtKB.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0030149; P:sphingolipid catabolic process; NAS:UniProtKB.
5O95470    568   SGPL1_HUMAN Sphingosine-1-phosphate lyase 1 O...5011e-128     396     41     61GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:UniProtKB.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; NAS:UniProtKB.
GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0006672; P:ceramide metabolic process; IDA:UniProtKB.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.::GO:0030149; P:sphingolipid catabolic process; NAS:UniProtKB.
6Q5R4G0    568   SGPL1_PONAB Sphingosine-1-phosphate lyase 1 O...5014e-127     392     41     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
7Q54RV9    528   SGPL_DICDI Sphingosine-1-phosphate lyase OS=D...4864e-127     390     42     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; ISS:dictyBase.
GO:0030036; P:actin cytoskeleton organization; IMP:dictyBase.::GO:0001667; P:ameboidal cell migration; IMP:dictyBase.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0008219; P:cell death; IMP:dictyBase.::GO:0006874; P:cellular calcium ion homeostasis; ISS:dictyBase.::GO:0006672; P:ceramide metabolic process; ISS:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0031276; P:negative regulation of lateral pseudopodium assembly; IMP:dictyBase.::GO:0046956; P:positive phototaxis; IMP:dictyBase.::GO:0030833; P:regulation of actin filament polymerization; ISS:dictyBase.::GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0030149; P:sphingolipid catabolic process; ISS:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
8Q9Y194    552   SGPL_CAEEL Sphingosine-1-phosphate lyase OS=C...4901e-121     377     42     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.
9Q9C509    544   SGPL_ARATH Sphingosine-1-phosphate lyase OS=A...4504e-117     365     43     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0030149; P:sphingolipid catabolic process; IMP:TAIR.
10Q52RG7    539   SGPL_ORYSJ Sphingosine-1-phosphate lyase OS=O...4805e-112     352     40     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
11Q5X3A8    605   SGPL_LEGPA Probable sphingosine-1-phosphate l...4882e-70     244     35     52
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
12Q5WUR6    605   SGPL_LEGPL Probable sphingosine-1-phosphate l...4874e-70     243     33     51
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
13Q5ZTI6    601   SGPL_LEGPH Probable sphingosine-1-phosphate l...4888e-69     239     35     51
GO:0016831; F:carboxy-lyase activity; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0008117; F:sphinganine-1-phosphate aldolase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
14O58679    383   MFNA_PYRHO L-tyrosine decarboxylase OS=NBRC 1...4122e-55     197     32     51
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
15Q8U1P6    371   MFNA_PYRFU L-tyrosine decarboxylase OS=Pyroco...3988e-55     195     33     52
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
16Q9UZD5    384   MFNA_PYRAB L-tyrosine decarboxylase OS=Pyroco...4099e-53     190     32     51
GO:0030170; F:pyridoxal phosphate binding; IEA:HAMAP.::GO:0004837; F:tyrosine decarboxylase activity; IEA:HAMAP.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
17O27188    363   MFNA_METTH L-tyrosine decarboxylase OS=thermo...3565e-51     185     32     52
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
18A5ULW4    385   MFNA_METS3 L-tyrosine decarboxylase OS=Methan...3942e-46     172     28     51
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
19C5A2X8    383   MFNA_THEGJ L-tyrosine decarboxylase OS=Thermo...3183e-44     166     33     52
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
20Q5JJ82    384   MFNA_PYRKO L-tyrosine decarboxylase OS=(Therm...2949e-43     162     35     52
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
21Q2NHY7    389   MFNA_METST L-tyrosine decarboxylase OS=Methan...3907e-38     148     28     48
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
22Q8PXA5    398   MFNA_METMA L-tyrosine decarboxylase OS=JCM 11...3552e-36     144     32     48
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
23A0B9M9    383   MFNA_METTP L-tyrosine decarboxylase OS=thermo...3571e-35     141     28     50
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
24Q0W498    375   MFNA_UNCMA L-tyrosine decarboxylase OS=Uncult...3512e-35     140     28     50
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
25Q12VA2    379   MFNA_METBU L-tyrosine decarboxylase OS=Methan...3649e-35     139     30     50
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
26Q46DU3    395   MFNA_METBF L-tyrosine decarboxylase OS=Methan...3661e-34     139     31     47
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
27Q8TUQ9    395   MFNA_METAC L-tyrosine decarboxylase OS=C2A). ...3775e-34     137     30     47
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
28Q8TV92    372   MFNA_METKA L-tyrosine decarboxylase OS=100938...3422e-33     134     28     46
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
29B8GDM7    363   MFNA_METPE L-tyrosine decarboxylase OS=Methan...2899e-31     127     31     49
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
30O28275    367   MFNA_ARCFU L-tyrosine decarboxylase OS=9628 /...3421e-30     127     27     49
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
31Q2FSD2    369   MFNA_METHJ L-tyrosine decarboxylase OS=Methan...3138e-30     124     30     49
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004837; F:tyrosine decarboxylase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
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