Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR291W
Length:
1077
Number of sequences:
5887
Description:
YDR291W HRQ1 SGDID:S000002699, Chr IV from 1039728-1042961, Genome Release 64-1-1, Uncharacterized ORF, "Putative RecQ helicase; belongs to the widely conserved RecQ family of proteins which are involved in maintaining genomic integrity; similar to the human RecQ4p implicated in Rothmund-Thomson syndrome(RTS)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O88700    1416   BLM_MOUSE Bloom syndrome protein homolog OS=M...3600.00000004     61.2     26     44GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001673; C:male germ cell nucleus; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0045120; C:pronucleus; IDA:MGI.::GO:0005657; C:replication fork; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0046632; P:alpha-beta T cell differentiation; IMP:MGI.::GO:0051276; P:chromosome organization; IMP:MGI.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IDA:MGI.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0045950; P:negative regulation of mitotic recombination; IMP:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0051098; P:regulation of binding; IDA:MGI.
32A7IB61    723   HELS_METB6 Putative ski2-type helicase OS=Met...3920.00000005     60.8     22     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
33Q9FT73    705   RQL2_ARATH ATP-dependent DNA helicase Q-like ...3510.00000006     60.5     22     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009378; F:four-way junction helicase activity; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0006310; P:DNA recombination; IC:TAIR.::GO:0006281; P:DNA repair; IC:TAIR.::GO:0006260; P:DNA replication; IEA:InterPro.
34A5DWJ1    399   FAL1_LODEL ATP-dependent RNA helicase FAL1 OS...3840.00000006     60.1     21     41GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
35Q5JGV6    1125   HELS_PYRKO Putative ski2-type helicase OS=(Th...3340.00000009     60.1     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:InterPro.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
36A2PYH4    1435   HFM1_HUMAN Probable ATP-dependent DNA helicas...3880.0000001     60.1     22     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
37Q55CI8    2237   HELCL_DICDI Activating signal cointegrator 1 ...3770.19     39.7     20     39GO:0005681; C:spliceosomal complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:dictyBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008380; P:RNA splicing; ISS:dictyBase.
38A6SCT6    592   DBP3_BOTFB ATP-dependent RNA helicase dbp3 OS...4020.0000005     57.4     23     40GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
39P35187    1447   SGS1_YEAST ATP-dependent helicase SGS1 OS=Sac...3880.0000007     57.4     23     40GO:0005730; C:nucleolus; IDA:SGD.::GO:0031422; C:RecQ helicase-Topo III complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006268; P:DNA unwinding involved in replication; IDA:SGD.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:SGD.::GO:0031292; P:gene conversion at mating-type locus, DNA double-strand break processing; IGI:SGD.::GO:0031573; P:intra-S DNA damage checkpoint; IMP:SGD.::GO:0045132; P:meiotic chromosome segregation; IMP:SGD.::GO:0000070; P:mitotic sister chromatid segregation; IMP:SGD.::GO:0010947; P:negative regulation of meiotic joint molecule formation; IGI:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0000722; P:telomere maintenance via recombination; IMP:SGD.::GO:0031860; P:telomeric 3' overhang formation; IGI:SGD.
40O18017    988   BLM_CAEEL Bloom syndrome protein homolog OS=C...3630.000001     57     23     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:WormBase.
GO:0006916; P:anti-apoptosis; IMP:WormBase.::GO:0051276; P:chromosome organization; IGI:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0000077; P:DNA damage checkpoint; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0051307; P:meiotic chromosome separation; IMP:WormBase.::GO:0007067; P:mitosis; IGI:WormBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:WormBase.::GO:0010165; P:response to X-ray; IMP:WormBase.
41Q5L3G9    467   CSHA_GEOKA DEAD-box ATP-dependent RNA helicas...3950.000001     55.8     24     41GO:0043590; C:bacterial nucleoid; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.
42P54132    1417   BLM_HUMAN Bloom syndrome protein OS=Homo sapi...3570.000002     55.8     25     44GO:0005737; C:cytoplasm; IDA:HPA.::GO:0000800; C:lateral element; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0000739; F:DNA strand annealing activity; IDA:UniProtKB.::GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.::GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.
GO:0000724; P:double-strand break repair via homologous recombination; NAS:UniProtKB.::GO:0000085; P:G2 phase of mitotic cell cycle; NAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; NAS:UniProtKB.::GO:0051782; P:negative regulation of cell division; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:UniProtKB.::GO:0031297; P:replication fork processing; IDA:UniProtKB.::GO:0048478; P:replication fork protection; NAS:UniProtKB.::GO:0010165; P:response to X-ray; IDA:UniProtKB.
43Q97AI2    674   HELS_THEVO Putative ski2-type helicase OS=154...4260.000002     55.5     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
44P46063    649   RECQ1_HUMAN ATP-dependent DNA helicase Q1 OS=...3500.000002     55.5     22     41GO:0015630; C:microtubule cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000739; F:DNA strand annealing activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0006260; P:DNA replication; IEA:InterPro.
45O60072    1935   MUG81_SCHPO Putative helicase mug81 OS=Schizo...3720.000002     55.8     23     42GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:2000765; P:regulation of cytoplasmic translation; ISS:PomBase.
46A7EYW0    596   DBP3_SCLS1 ATP-dependent RNA helicase dbp3 OS...4080.000002     55.1     22     39GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
47Q8PZR7    730   HELS_METMA Putative ski2-type helicase OS=JCM...3880.000003     55.1     22     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
48Q0WVW7    911   RQL5_ARATH ATP-dependent DNA helicase Q-like ...3600.000003     55.1     23     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0042631; P:cellular response to water deprivation; IEP:UniProtKB.::GO:0006310; P:DNA recombination; IEA:InterPro.
49Q8TL39    730   HELS_METAC Putative ski2-type helicase OS=C2A...3890.000004     54.7     22     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
50Q465R3    729   HELS_METBF Putative ski2-type helicase OS=Met...3850.000004     54.7     23     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
51Q5RF63    649   RECQ1_PONAB ATP-dependent DNA helicase Q1 OS=...3500.000005     54.3     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.
52O94762    991   RECQ5_HUMAN ATP-dependent DNA helicase Q5 OS=...3720.000006     54.3     23     37GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003678; F:DNA helicase activity; NAS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:ProtInc.
53P27639    402   IF4A_CAEEL Eukaryotic initiation factor 4A OS...4090.000006     53.5     21     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
54Q9CL21    632   RECQ_PASMU ATP-dependent DNA helicase recQ OS...3590.000006     53.9     21     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0009432; P:SOS response; IEA:InterPro.
55O93530    1436   WRN_XENLA Werner syndrome ATP-dependent helic...3730.000007     54.3     22     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008408; F:3'-5' exonuclease activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB.
GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:InterPro.
56P73421    478   RECQ_SYNY3 ATP-dependent DNA helicase recQ OS...1110.00001     53.1     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:InterPro.
57Q14191    1432   WRN_HUMAN Werner syndrome ATP-dependent helic...1000.00001     53.5     29     50GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:MGI.
GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.::GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0000403; F:Y-form DNA binding; IDA:UniProtKB.
GO:0006284; P:base-excision repair; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IDA:MGI.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0000731; P:DNA synthesis involved in DNA repair; IDA:UniProtKB.::GO:0010259; P:multicellular organismal aging; IMP:UniProtKB.::GO:0032066; P:nucleolus to nucleoplasm transport; IDA:MGI.::GO:0051345; P:positive regulation of hydrolase activity; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IGI:MGI.::GO:0031297; P:replication fork processing; IDA:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.::GO:0010225; P:response to UV-C; IDA:UniProtKB.::GO:0000723; P:telomere maintenance; IMP:UniProtKB.
58Q3IU46    747   HELS_NATPD Putative ski2-type helicase OS=Nat...4070.00002     52.8     23     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
59Q55D61    405   IF4A_DICDI Eukaryotic initiation factor 4A OS...3890.00002     52.4     22     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
60O75417    2590   DPOLQ_HUMAN DNA polymerase theta OS=Homo sapi...4430.00002     53.1     20     39GO:0005654; C:nucleoplasm; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003684; F:damaged DNA binding; TAS:ProtInc.::GO:0003887; F:DNA-directed DNA polymerase activity; IDA:UniProtKB.::GO:0043142; F:single-stranded DNA-dependent ATPase activity; IDA:UniProtKB.
GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0006260; P:DNA replication; IEA:InterPro.
61Q54G57    2195   HELC1_DICDI Activating signal cointegrator 1 ...3961.3     37     21     37
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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