Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR283C
Length:
1659
Number of sequences:
5887
Description:
YDR283C GCN2 SGDID:S000002691, Chr IV from 1030049-1025070, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
631Q5REX1    925   SIK2_PONAB Serine/threonine-protein kinase SI...1900.039     42.4     25     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
632Q55FS2    1105   STK4L_DICDI Serine/threonine-protein kinase 4...710.039     42.4     30     54GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
633Q2RBF0    434   CIPKF_ORYSJ CBL-interacting protein kinase 15...2310.04     42     22     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
634Q9DB30    406   PHKG2_MOUSE Phosphorylase b kinase gamma cata...1750.04     42     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
635Q8VHJ5    795   MARK1_MOUSE Serine/threonine-protein kinase M...1370.04     42.4     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0070300; F:phosphatidic acid binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
636Q2QYM3    439   CIPKE_ORYSJ CBL-interacting protein kinase 14...2310.042     42     22     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
637O15530    556   PDPK1_HUMAN 3-phosphoinositide-dependent prot...750.043     42     33     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
638P13234    474   KCC4_RAT Calcium/calmodulin-dependent protein...2070.043     42     25     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.
639O08678    793   MARK1_RAT Serine/threonine-protein kinase MAR...1370.045     42.4     27     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; NAS:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0070300; F:phosphatidic acid binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IDA:RGD.::GO:0001764; P:neuron migration; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
640Q92918    833   M4K1_HUMAN Mitogen-activated protein kinase k...600.046     42.4     30     62
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008349; F:MAP kinase kinase kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
641O54748    491   STK3_RAT Serine/threonine-protein kinase 3 OS...2220.046     42     24     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
642O14328    474   KSP1_SCHPO Serine/threonine-protein kinase ks...1940.047     42     25     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
643Q61846    643   MELK_MOUSE Maternal embryonic leucine zipper ...2410.048     42     22     41GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
644Q05006    294   CDC22_MEDSA Cell division control protein 2 h...620.049     41.2     35     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
645Q03957    528   CTK1_YEAST CTD kinase subunit alpha OS=Saccha...960.049     42     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005654; C:nucleoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:SGD.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:SGD.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IDA:SGD.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0045903; P:positive regulation of translational fidelity; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
646F1NBT0    969   STK10_CHICK Serine/threonine-protein kinase 1...1750.049     42     24     45GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
647Q924X7    491   STK33_MOUSE Serine/threonine-protein kinase 3...2370.05     42     21     39GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
648Q9H093    628   NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS...620.051     42     37     60
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
649Q5R7G9    628   NUAK2_PONAB NUAK family SNF1-like kinase 2 OS...620.052     42     37     60
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
650P29618    294   CDKA1_ORYSJ Cyclin-dependent kinase A-1 OS=Or...1080.053     41.2     29     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
651Q8BPM2    847   M4K5_MOUSE Mitogen-activated protein kinase k...720.054     42     28     50GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.
652P08458    490   SPS1_YEAST Sporulation-specific protein 1 OS=...680.054     41.6     32     51GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005628; C:prospore membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
653Q99JT2    416   MST4_MOUSE Serine/threonine-protein kinase MS...2170.054     41.6     26     42GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
654Q6A1A2    396   PDPK2_HUMAN Putative 3-phosphoinositide-depen...750.054     41.6     33     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
655Q9Y4K4    846   M4K5_HUMAN Mitogen-activated protein kinase k...720.056     42     28     50GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
656Q38772    294   CDC2A_ANTMA Cell division control protein 2 h...620.059     41.2     35     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
657Q23356    1096   MIG15_CAEEL Serine/threonine-protein kinase m...1740.06     42     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IGI:WormBase.::GO:0033563; P:dorsal/ventral axon guidance; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
658Q8XJL8    685   PKN2_CLOPE Probable serine/threonine-protein ...1920.061     41.6     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
659Q9R1U5    776   SIK1_RAT Serine/threonine-protein kinase SIK1...2440.061     41.6     24     44GO:0005829; C:cytosol; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008140; F:cAMP response element binding protein binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0055007; P:cardiac muscle cell differentiation; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; IDA:UniProtKB.
660P93759    530   CDPKE_ARATH Calcium-dependent protein kinase ...2630.064     41.6     22     43GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
661O88445    282   AURKC_MOUSE Aurora kinase C OS=Mus musculus (...2450.064     40.8     23     42GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
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