Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR283C
Length:
1659
Number of sequences:
5887
Description:
YDR283C GCN2 SGDID:S000002691, Chr IV from 1030049-1025070, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P15442    1659   GCN2_YEAST Serine/threonine-protein kinase GC...16590     3417     100     100GO:0022626; C:cytosolic ribosome; IDA:SGD.
GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:SGD.::GO:0000049; F:tRNA binding; IEA:InterPro.
GO:0008652; P:cellular amino acid biosynthetic process; IMP:SGD.::GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.::GO:0006412; P:translation; IEA:UniProtKB-KW.
2Q9HGN1    1576   GCN2_SCHPO Serine/threonine-protein kinase gc...14910     685     32     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:PomBase.::GO:0042803; F:protein homodimerization activity; ISS:PomBase.::GO:0000049; F:tRNA binding; IEA:InterPro.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0031575; P:mitotic cell cycle G1/S transition checkpoint; IMP:PomBase.::GO:0071263; P:negative regulation of translational initiation in response to starvation; TAS:PomBase.::GO:0043561; P:regulation of translational initiation in response to osmotic stress; IGI:PomBase.
3Q9QZ05    1648   E2AK4_MOUSE Eukaryotic translation initiation...15302e-111     394     27     44GO:0022626; C:cytosolic ribosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:InterPro.
GO:0009267; P:cellular response to starvation; IDA:MGI.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:MGI.::GO:0017148; P:negative regulation of translation; IGI:MGI.::GO:0043558; P:regulation of translational initiation in response to stress; IDA:MGI.
4Q4R8E0    631   E2AK1_MACFA Eukaryotic translation initiation...4388e-46     181     35     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0017148; P:negative regulation of translation; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:InterPro.
5Q9Z2R9    619   E2AK1_MOUSE Eukaryotic translation initiation...4412e-45     179     33     50GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; ISS:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0046986; P:negative regulation of hemoglobin biosynthetic process; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IEP:UniProtKB.::GO:0009605; P:response to external stimulus; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.
6Q9BQI3    630   E2AK1_HUMAN Eukaryotic translation initiation...4411e-44     177     34     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0046986; P:negative regulation of hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0045993; P:negative regulation of translational initiation by iron; NAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0009605; P:response to external stimulus; IEP:UniProtKB.::GO:0006950; P:response to stress; IEP:UniProtKB.
7P33279    626   E2AK1_RABIT Eukaryotic translation initiation...4462e-43     174     30     47GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046986; P:negative regulation of hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0009605; P:response to external stimulus; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.
8O13889    704   E2AK1_SCHPO Eukaryotic translation initiation...5081e-37     156     32     45GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0032063; P:negative regulation of translational initiation in response to osmotic stress; IGI:PomBase.
9Q86AS6    481   SYHC_DICDI Histidine--tRNA ligase, cytoplasmi...4112e-24     112     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004821; F:histidine-tRNA ligase activity; ISS:dictyBase.
GO:0006427; P:histidyl-tRNA aminoacylation; ISS:dictyBase.
10P93422    788   SYH_ORYSJ Histidine--tRNA ligase OS=Oryza sat...4601e-22     108     24     47GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0016841; F:ammonia-lyase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004821; F:histidine-tRNA ligase activity; IEA:EC.
GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
11Q55GU0    916   Y9955_DICDI Probable serine/threonine-protein...2148e-22     106     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
12Q54RP7    637   Y0652_DICDI Probable serine/threonine-protein...1891e-21     105     37     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
13P70076    519   SYHC_TAKRU Histidine--tRNA ligase, cytoplasmi...4894e-21     102     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004821; F:histidine-tRNA ligase activity; IEA:EC.
GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
14O22932    435   CIPKB_ARATH CBL-interacting serine/threonine-...2507e-21     101     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009268; P:response to pH; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
15Q2V452    441   CIPK3_ARATH CBL-interacting serine/threonine-...2268e-21     100     30     48GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0009628; P:response to abiotic stimulus; IEP:TAIR.::GO:0009735; P:response to cytokinin stimulus; IEP:TAIR.
16Q2KI84    509   SYHC_BOVIN Histidine--tRNA ligase, cytoplasmi...4849e-21     101     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004821; F:histidine-tRNA ligase activity; IEA:EC.
GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
17Q9LWM4    461   CIPK5_ORYSJ CBL-interacting protein kinase 5 ...2431e-20     100     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
18A3B529    435   CIPKS_ORYSJ CBL-interacting protein kinase 28...2271e-20     100     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
19Q9FJ54    439   CIPKK_ARATH CBL-interacting serine/threonine-...2621e-20     100     26     47GO:0005829; C:cytosol; TAS:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:TAIR.
GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
20P92937    421   CIPKF_ARATH CBL-interacting serine/threonine-...2262e-20     99.8     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:TAIR.
21Q10LQ2    451   CIPKA_ORYSJ CBL-interacting protein kinase 10...2253e-20     99.4     26     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
22P12081    509   SYHC_HUMAN Histidine--tRNA ligase, cytoplasmi...4833e-20     100     24     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004821; F:histidine-tRNA ligase activity; NAS:UniProtKB.
GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
23Q61035    509   SYHC_MOUSE Histidine--tRNA ligase, cytoplasmi...4836e-20     99.4     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004821; F:histidine-tRNA ligase activity; IEA:EC.
GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
24Q5R4R2    509   SYHC_PONAB Histidine--tRNA ligase, cytoplasmi...4837e-20     99     24     47GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004821; F:histidine-tRNA ligase activity; IEA:EC.
GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
25A5D7V9    506   SYHM_BOVIN Probable histidine--tRNA ligase, m...4449e-20     98.6     25     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004821; F:histidine-tRNA ligase activity; IEA:EC.
GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
26Q8C0N0    497   SMKZ_MOUSE Sperm motility kinase Z OS=Mus mus...2159e-20     98.6     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
27Q6ZLP5    450   CIPKN_ORYSJ CBL-interacting protein kinase 23...2331e-19     97.4     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
28Q8S9D1    831   PP395_ARATH Pentatricopeptide repeat-containi...2404e-19     97.8     29     46
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
29Q75JN1    1700   IFKC_DICDI Probable serine/threonine-protein ...848e-19     97.4     56     74
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000049; F:tRNA binding; IEA:InterPro.
30Q5JLD8    446   CIPK8_ORYSJ CBL-interacting protein kinase 8 ...2448e-19     95.1     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
31Q5W736    457   CIPKI_ORYSJ CBL-interacting protein kinase 18...2341e-18     94.7     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
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