Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR265W
Length:
337
Number of sequences:
5887
Description:
YDR265W PEX10 SGDID:S000002673, Chr IV from 998864-999877, Genome Release 64-1-1, Verified ORF, "Peroxisomal membrane E3 ubiquitin ligase, required for for Ubc4p-dependent Pex5p ubiquitination and peroxisomal matrix protein import; contains zinc-binding RING domain; mutations in human homolog cause various peroxisomal disorders"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451Q9VE61    147   RN181_DROME E3 ubiquitin-protein ligase RNF18...252.6     32.3     48     60
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
452Q07G17    242   PCGF3_XENTR Polycomb group RING finger protei...442.6     33.1     39     50GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
453P38748    585   ETP1_YEAST RING finger protein ETP1 OS=Saccha...442.6     33.5     36     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045471; P:response to ethanol; IMP:SGD.
454P28284    825   ICP0_HHV2H E3 ubiquitin-protein ligase ICP0 O...412.7     33.5     39     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
455Q6P9F5    258   TRI40_HUMAN Tripartite motif-containing prote...532.8     33.1     34     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
456Q5M7X9    341   MUL1A_DANRE Mitochondrial ubiquitin ligase ac...422.8     33.5     38     55GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.::GO:0005777; C:peroxisome; ISS:UniProtKB.
GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0000266; P:mitochondrial fission; ISS:UniProtKB.::GO:0051646; P:mitochondrion localization; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.
457A5WW08    637   CHFR_DANRE E3 ubiquitin-protein ligase CHFR O...452.8     33.5     40     49GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
458Q9Z2Y9    1014   KLOT_RAT Klotho OS=Rattus norvegicus (Rat). G...802.9     33.5     35     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004566; F:beta-glucuronidase activity; IEA:EC.::GO:0043169; F:cation binding; IEA:InterPro.
GO:0002526; P:acute inflammatory response; IDA:RGD.::GO:0007568; P:aging; TAS:RGD.::GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
459Q8BTQ0    241   PCGF3_MOUSE Polycomb group RING finger protei...402.9     33.1     40     53GO:0031519; C:PcG protein complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
460Q8GX84    343   C3H1_ARATH Zinc finger CCCH domain-containing...522.9     33.1     31     40
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
461Q9FNG6    378   C3H51_ARATH Zinc finger CCCH domain-containin...522.9     33.1     31     40GO:0016020; C:membrane; IDA:TAIR.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
462Q5FWL3    317   RNF41_XENLA E3 ubiquitin-protein ligase NRDP1...403     33.1     35     55
GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
463Q8IWT3    2517   CUL9_HUMAN Cullin-9 OS=Homo sapiens (Human). ...173     33.5     65     71GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
464B6CJY4    522   TRAF6_CERAT TNF receptor-associated factor 6 ...433     33.5     33     60GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
465Q99PQ1    284   TR12A_MOUSE Tripartite motif-containing prote...453     33.1     38     51GO:0005737; C:cytoplasm; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
466Q76R05    242   P28_VAR67 E3 ubiquitin-protein ligase p28-lik...313     33.1     39     55GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
467Q1ACD7    494   TRIM5_NOMLE Tripartite motif-containing prote...463     33.5     39     52GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
468Q5R7T5    317   RNF41_PONAB E3 ubiquitin-protein ligase NRDP1...403.1     33.1     35     55
GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
469Q9H4P4    317   RNF41_HUMAN E3 ubiquitin-protein ligase NRDP1...403.1     33.1     35     55GO:0005829; C:cytosol; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
470B6CJY5    522   TRAF6_MACMU TNF receptor-associated factor 6 ...433.1     33.5     33     60GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
471P19474    475   RO52_HUMAN E3 ubiquitin-protein ligase TRIM21...413.1     33.5     39     49GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; IMP:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0070206; P:protein trimerization; IDA:UniProtKB.
472Q63364    707   PJA2_RAT E3 ubiquitin-protein ligase Praja-2 ...303.1     33.5     40     57GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0034236; F:protein kinase A catalytic subunit binding; ISS:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007616; P:long-term memory; IMP:UniProtKB.::GO:0010738; P:regulation of protein kinase A signaling cascade; IMP:UniProtKB.
473Q9SRX9    335   BAH1_ARATH E3 ubiquitin-protein ligase BAH1 O...513.1     33.1     31     47GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; TAS:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0009626; P:plant-type hypersensitive response; IMP:TAIR.::GO:0010337; P:regulation of salicylic acid metabolic process; IMP:TAIR.::GO:0080021; P:response to benzoic acid stimulus; IEP:TAIR.::GO:0010167; P:response to nitrate; IMP:TAIR.::GO:0009751; P:response to salicylic acid stimulus; IEP:TAIR.::GO:0009697; P:salicylic acid biosynthetic process; IMP:TAIR.::GO:0009627; P:systemic acquired resistance; IMP:TAIR.
474Q9Y4K3    522   TRAF6_HUMAN TNF receptor-associated factor 6 ...433.1     33.5     33     60GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0043422; F:protein kinase B binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; NAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
475P87607    242   P28_CWPXG E3 ubiquitin-protein ligase p28-lik...313.1     32.7     39     55GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
476Q8QN38    242   P28_CWPXB E3 ubiquitin-protein ligase p28-lik...313.1     32.7     39     55GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
477Q60803    567   TRAF3_MOUSE TNF receptor-associated factor 3 ...673.1     33.5     30     46GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.
GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0050688; P:regulation of defense response to virus; IMP:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; IDA:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.
478Q1ACD6    494   TRIM5_HYLSY Tripartite motif-containing prote...463.1     33.5     39     52GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
479Q5RKG6    501   TRI35_RAT Tripartite motif-containing protein...503.1     33.5     36     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
480Q8BH75    317   RNF41_MOUSE E3 ubiquitin-protein ligase NRDP1...403.2     33.1     35     55
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0031386; F:protein tag; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
481Q6IWL4    542   TRAF6_DANRE TNF receptor-associated factor 6 ...303.2     33.5     43     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; IMP:ZFIN.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:ZFIN.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0009617; P:response to bacterium; IDA:ZFIN.::GO:0009615; P:response to virus; IDA:ZFIN.::GO:0007165; P:signal transduction; IEA:InterPro.
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