Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR265W
Length:
337
Number of sequences:
5887
Description:
YDR265W PEX10 SGDID:S000002673, Chr IV from 998864-999877, Genome Release 64-1-1, Verified ORF, "Peroxisomal membrane E3 ubiquitin ligase, required for for Ubc4p-dependent Pex5p ubiquitination and peroxisomal matrix protein import; contains zinc-binding RING domain; mutations in human homolog cause various peroxisomal disorders"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331Q8BGE7    488   TRIM6_MOUSE Tripartite motif-containing prote...510.62     35.4     33     47GO:0005737; C:cytoplasm; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
332Q5RF77    571   CHFR_PONAB E3 ubiquitin-protein ligase CHFR O...650.62     35.4     31     45GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
333O70277    744   TRIM3_RAT Tripartite motif-containing protein...430.63     35.8     37     49GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
334Q5D7I1    547   TRIM5_ATEGE Tripartite motif-containing prote...450.63     35.4     38     53GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
335C8VCP8    489   PEX12_EMENI Peroxisome assembly protein 12 OS...680.64     35.4     24     51GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008022; F:protein C-terminus binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006625; P:protein targeting to peroxisome; IEA:InterPro.
336Q6AXU4    165   RN181_RAT E3 ubiquitin-protein ligase RNF181 ...470.64     34.7     36     51
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
337Q8CIK8    774   RFWD3_MOUSE E3 ubiquitin-protein ligase RFWD3...940.65     35.8     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
338Q6IMG5    396   NHLC1_RAT E3 ubiquitin-protein ligase NHLRC1 ...360.65     35.4     39     56GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
339Q2U9B0    760   BRE1_ASPOR E3 ubiquitin-protein ligase bre1 O...390.66     35.4     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
340Q8LPN7    328   RNG1L_ARATH E3 ubiquitin-protein ligase RING1...440.66     35.4     34     50
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
341Q95153    1878   BRCA1_CANFA Breast cancer type 1 susceptibili...430.66     35.8     33     56GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
342Q9FF61    881   SM3L1_ARATH Putative SWI/SNF-related matrix-a...400.68     35.4     33     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
343Q62191    470   RO52_MOUSE E3 ubiquitin-protein ligase TRIM21...420.68     35.4     40     48GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
344Q96F44    468   TRI11_HUMAN E3 ubiquitin-protein ligase TRIM1...440.69     35.4     41     52GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009615; P:response to virus; IEA:UniProtKB-KW.
345A0JN74    468   TRI11_BOVIN E3 ubiquitin-protein ligase TRIM1...440.69     35.4     41     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009615; P:response to virus; IEA:UniProtKB-KW.
346Q9LZV8    159   ATL74_ARATH RING-H2 finger protein ATL74 OS=A...480.72     34.3     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
347Q5RD97    726   RN219_PONAB RING finger protein 219 OS=Pongo ...450.74     35.4     33     47
GO:0008270; F:zinc ion binding; IEA:InterPro.
348P78317    190   RNF4_HUMAN E3 ubiquitin-protein ligase RNF4 O...640.75     34.7     28     39GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0031491; F:nucleosome binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0032184; F:SUMO polymer binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; IMP:UniProtKB.::GO:0090169; P:regulation of spindle assembly; IMP:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
349E9QAU8    347   RN165_MOUSE RING finger protein 165 OS=Mus mu...470.76     35     34     47
GO:0008270; F:zinc ion binding; IEA:InterPro.
350Q99PQ2    467   TRI11_MOUSE E3 ubiquitin-protein ligase TRIM1...440.79     35     41     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0050768; P:negative regulation of neurogenesis; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
351Q6ZSG1    346   RN165_HUMAN RING finger protein 165 OS=Homo s...470.79     35     34     47
GO:0008270; F:zinc ion binding; IEA:InterPro.
352Q96EP1    664   CHFR_HUMAN E3 ubiquitin-protein ligase CHFR O...650.79     35.4     31     45GO:0016605; C:PML body; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
353B1H278    467   TRI11_RAT E3 ubiquitin-protein ligase TRIM11 ...440.8     35     41     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009615; P:response to virus; IEA:UniProtKB-KW.
354Q9FKX5    221   NIPL1_ARATH NEP1-interacting protein-like 1 O...460.8     34.7     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010200; P:response to chitin; IEP:TAIR.
355Q32NQ8    756   RNF10_XENLA RING finger protein 10 OS=Xenopus...420.81     35.4     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010626; P:negative regulation of Schwann cell proliferation; ISS:UniProtKB.::GO:0031643; P:positive regulation of myelination; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
356Q9Y252    685   RNF6_HUMAN E3 ubiquitin-protein ligase RNF6 O...820.83     35.4     27     44GO:0030424; C:axon; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030517; P:negative regulation of axon extension; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
357Q5D7H7    547   TRIM5_LAGLA Tripartite motif-containing prote...450.84     35     38     53GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
358Q803C1    485   RNF8_DANRE E3 ubiquitin-protein ligase RNF8 O...560.87     35     27     46GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
359Q7ZUL9    529   MGRN1_DANRE Probable E3 ubiquitin-protein lig...450.88     35     33     56
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
360Q8TDB6    740   DTX3L_HUMAN E3 ubiquitin-protein ligase DTX3L...400.91     35     33     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.
361Q8BR37    401   NHLC1_MOUSE E3 ubiquitin-protein ligase NHLRC...360.96     35     39     56GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031398; P:positive regulation of protein ubiquitination; IDA:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
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