Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR264C
Length:
764
Number of sequences:
5887
Description:
YDR264C AKR1 SGDID:S000002672, Chr IV from 998323-996029, Genome Release 64-1-1, reverse complement, Verified ORF, "Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q00653    900   NFKB2_HUMAN Nuclear factor NF-kappa-B p100 su...2310.0001     49.3     28     39GO:0033257; C:Bcl3/NF-kappaB2 complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
182Q9J4Z6    668   V244_FOWPN Putative ankyrin repeat protein FP...2090.00009     49.7     25     44
183Q15327    319   ANKR1_HUMAN Ankyrin repeat domain-containing ...760.055     40     37     49GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0031674; C:I band; ISS:BHF-UCL.
GO:0003677; F:DNA binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0002039; F:p53 binding; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL.::GO:0003714; F:transcription corepressor activity; TAS:BHF-UCL.
GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071347; P:cellular response to interleukin-1; IDA:BHF-UCL.::GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IDA:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0071356; P:cellular response to tumor necrosis factor; IDA:BHF-UCL.::GO:2000279; P:negative regulation of DNA biosynthetic process; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.::GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.::GO:0035994; P:response to muscle stretch; IMP:BHF-UCL.::GO:0045214; P:sarcomere organization; NAS:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
184Q8TC84    345   FANK1_HUMAN Fibronectin type 3 and ankyrin re...1050.00009     48.9     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
185Q5UPE2    580   YL063_MIMIV Putative ankyrin repeat protein L...1050.12     39.7     25     50
186Q4UJ75    823   A20A4_HUMAN Ankyrin repeat domain-containing ...2250.00000001     62.4     27     41
187Q5UQZ7    361   YR901_MIMIV Putative ankyrin repeat protein R...1580.0002     47.8     27     51
188A6NC57    917   ANR62_HUMAN Ankyrin repeat domain-containing ...1990.00000001     62     31     44
189Q29RM5    653   FEM1A_BOVIN Protein fem-1 homolog A OS=Bos ta...1660.0001     48.9     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.
190Q9DAM9    344   FANK1_MOUSE Fibronectin type 3 and ankyrin re...1050.0003     47.8     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
191Q9BXX3    1397   AN30A_HUMAN Ankyrin repeat domain-containing ...2010.00000002     62     27     42GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
192Q8N283    1001   ANR35_HUMAN Ankyrin repeat domain-containing ...920.29     38.5     28     46
193P17221    656   FEM1_CAEEL Sex-determining protein fem-1 OS=C...1650.00002     51.6     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0019100; P:male germ-line sex determination; IMP:WormBase.::GO:0019102; P:male somatic sex determination; IMP:WormBase.::GO:0042006; P:masculinization of hermaphroditic germ-line; IMP:WormBase.
194Q5UP14    224   YR845_MIMIV Putative ankyrin repeat protein R...1870.000006     51.6     24     42
195Q8VHQ3    568   PP16B_MOUSE Protein phosphatase 1 regulatory ...1461.3     36.2     25     40GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.
196Q60J38    2636   ANKHM_CAEBR Ankyrin repeat and KH domain-cont...1950.0004     48.1     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
197Q1RK13    826   Y220_RICBR Putative ankyrin repeat protein RB...1062.7     35     29     49
198Q9VUX2    1226   MIB_DROME E3 ubiquitin-protein ligase mind-bo...710.006     43.9     35     48GO:0045179; C:apical cortex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0046331; P:lateral inhibition; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB.::GO:0007423; P:sensory organ development; IMP:FlyBase.
199Q7XUW4    719   KOR2_ORYSJ Potassium channel KOR2 OS=Oryza sa...2940.00000002     61.6     25     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
200Q9J516    434   V219_FOWPN Putative ankyrin repeat protein FP...1550.0005     47     25     47
GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
201Q66H07    344   FANK1_RAT Fibronectin type 3 and ankyrin repe...1050.0002     47.8     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
202A1X154    477   ASZ1_ECHTE Ankyrin repeat, SAM and basic leuc...1450.000002     54.7     26     40GO:0071546; C:pi-body; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.::GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0007140; P:male meiosis; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
203Q5GIG6    834   TNI3K_MOUSE Serine/threonine-protein kinase T...1040.046     40.8     33     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
204Q9WV06    358   ANKR2_MOUSE Ankyrin repeat domain-containing ...1550.3     37.7     25     41GO:0031674; C:I band; IDA:MGI.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0031432; F:titin binding; IPI:UniProtKB.
205Q9Y575    518   ASB3_HUMAN Ankyrin repeat and SOCS box protei...1558.3     33.5     22     43
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
206Q8R516    973   MIB2_MOUSE E3 ubiquitin-protein ligase MIB2 O...750.024     42     33     48GO:0005769; C:early endosome; IDA:MGI.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
207O75179    2603   ANR17_HUMAN Ankyrin repeat domain-containing ...1870.009     43.5     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
208Q5URB9    526   YR840_MIMIV Putative ankyrin repeat protein R...1140.034     41.2     32     46
209Q9QW30    2471   NOTC2_RAT Neurogenic locus notch homolog prot...632.8     35.4     33     48GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004872; F:receptor activity; TAS:RGD.
GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0001709; P:cell fate determination; IDA:RGD.::GO:0016049; P:cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0050793; P:regulation of developmental process; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042246; P:tissue regeneration; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
210Q04721    2471   NOTC2_HUMAN Neurogenic locus notch homolog pr...632.8     35.4     33     48GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0003706; F:ligand-regulated transcription factor activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; NAS:UniProtKB.
GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0046849; P:bone remodeling; IMP:UniProtKB.::GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0001709; P:cell fate determination; TAS:UniProtKB.::GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; TAS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; IEP:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0019827; P:stem cell maintenance; TAS:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
211Q00PJ3    475   ASZ1_ATEAB Ankyrin repeat, SAM and basic leuc...910.004     43.9     34     51GO:0071546; C:pi-body; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.::GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0007140; P:male meiosis; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
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