UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR263C

Length:

430

Number of sequences:

5887

Description:

YDR263C DIN7 SGDID:S000002671, Chr IV from 995534-994242, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
181	Q4Z015	478	FEN1_PLABA Flap endonuclease 1 OS=Plasmodium ...	283	0.00000000006	67.8	26	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
182	A1RSC7	346	FEN_PYRIL Flap endonuclease 1 OS=Pyrobaculum ...	264	0.00000000009	66.6	24	44
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
183	Q91FF5	415	VF369_IIV6 Probable RAD2-like endonuclease 36...	298	0.0000000001	66.6	23	43	GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:InterPro.
184	B6JYI7	377	FEN1_SCHJY Flap endonuclease 1 OS=yeast). GN=...	243	0.0000000002	65.9	22	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
185	Q18HK0	326	FEN_HALWD Flap endonuclease 1 OS=Haloquadratu...	326	0.0000000002	65.1	20	38
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
186	C6A1U9	340	FEN_THESM Flap endonuclease 1 OS=Thermococcus...	279	0.0000000002	65.5	28	44
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
187	A3MY15	346	FEN_PYRCJ Flap endonuclease 1 OS=Pyrobaculum ...	262	0.0000000003	64.7	24	44
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
188	P61942	339	FEN_NANEQ Flap endonuclease 1 OS=Nanoarchaeum...	249	0.0000000004	64.7	24	44
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
189	P14629	1196	ERCC5_XENLA DNA repair protein complementing ...	95	0.024	40.8	29	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
									GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
190	Q8TIY5	338	FEN_METAC Flap endonuclease 1 OS=C2A). GN=fen...	257	0.0000000005	64.3	25	44
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
191	P28706	1112	RAD13_SCHPO DNA repair protein rad13 OS=Schiz...	120	0.00003	50.4	30	53	GO:0005634; C:nucleus; IDA:PomBase.
									GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
									GO:0006295; P:nucleotide-excision repair, DNA incision, 3'-to lesion; TAS:PomBase.
192	P28715	1186	ERCC5_HUMAN DNA repair protein complementing ...	96	0.0004	46.6	32	51	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.::GO:0004520; F:endodeoxyribonuclease activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
									GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.::GO:0006295; P:nucleotide-excision repair, DNA incision, 3'-to lesion; IDA:UniProtKB.::GO:0010225; P:response to UV-C; IMP:UniProtKB.::GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:UniProtKB.::GO:0009650; P:UV protection; IGI:MGI.
193	B0E412	469	FEN12_LACBS Flap endonuclease 1-B OS=deceiver...	267	0.000000001	63.5	27	43	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
194	P07276	1031	RAD2_YEAST DNA repair protein RAD2 OS=Sacchar...	110	2.9	34.3	25	44	GO:0000112; C:nucleotide-excision repair factor 3 complex; IDA:SGD.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.::GO:0000014; F:single-stranded DNA specific endodeoxyribonuclease activity; IDA:SGD.
									GO:0006295; P:nucleotide-excision repair, DNA incision, 3'-to lesion; IMP:SGD.
195	Q4DKQ5	393	FEN1_TRYCC Flap endonuclease 1 OS=Trypanosoma...	250	0.000000001	63.2	24	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
196	P35689	1170	ERCC5_MOUSE DNA repair protein complementing ...	96	0.007	42.4	31	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
									GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
197	B1YC46	349	FEN_THENV Flap endonuclease 1 OS=Thermoproteu...	266	0.000000002	62.4	24	43
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
198	C9ZKW4	393	FEN1_TRYB9 Flap endonuclease 1 OS=Trypanosoma...	256	0.000000004	61.6	25	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
199	Q57WW6	393	FEN1_TRYB2 Flap endonuclease 1 OS=Trypanosoma...	256	0.000000004	61.6	25	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
200	Q17RS7	908	GEN_HUMAN Flap endonuclease GEN homolog 1 OS=...	246	0.000000006	61.6	22	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
201	B8C6S5	390	FEN1_THAPS Flap endonuclease 1 OS=Thalassiosi...	276	0.00000002	59.7	26	42	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
202	Q8BMI4	908	GEN_MOUSE Flap endonuclease GEN homolog 1 OS=...	246	0.00000004	59.3	22	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
203	O93634	340	FEN_PYRFU Flap endonuclease 1 OS=Pyrococcus f...	261	0.00000005	58.2	26	44
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
204	Q6GZN0	363	095R_FRG3G Putative RAD2-like endonuclease 09...	299	0.0000001	57.4	25	42	GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:InterPro.
205	Q5UQW7	473	YL386_MIMIV Putative endonuclease L386 OS=Aca...	211	0.0000004	55.5	27	43
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:InterPro.
206	Q5JGN0	340	FEN_PYRKO Flap endonuclease 1 OS=(Thermococcu...	247	0.0000005	54.7	25	42
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
207	Q8TXU4	348	FEN_METKA Flap endonuclease 1 OS=100938). GN=...	203	0.000002	53.1	25	44
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
208	C5A639	339	FEN_THEGJ Flap endonuclease 1 OS=Thermococcus...	247	0.000009	50.8	24	41
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
209	Q9HQ27	327	FEN_HALSA Flap endonuclease 1 OS=(Halobacteri...	256	0.00002	50.1	22	41
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
210	B0R5F5	327	FEN_HALS3 Flap endonuclease 1 OS=Halobacteriu...	256	0.00002	50.1	22	41
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
211	B6YWX4	341	FEN_THEON Flap endonuclease 1 OS=Thermococcus...	247	0.00005	48.5	24	41
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.

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