Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR259C
Length:
383
Number of sequences:
5887
Description:
YDR259C YAP6 SGDID:S000002667, Chr IV from 975782-974631, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative basic leucine zipper (bZIP) transcription factor; physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets; overexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulation of expression of genes involved in carbohydrate metabolism"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q03935    383   YAP6_YEAST AP-1-like transcription factor YAP...3830     773     100     100GO:0005634; C:nucleus; IDA:SGD.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
2P40917    295   YAP4_YEAST AP-1-like transcription factor YAP...652e-20     94     66     85GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0070491; F:repressing transcription factor binding; IDA:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0042538; P:hyperosmotic salinity response; IMP:SGD.::GO:0042493; P:response to drug; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q54WN7    631   BZPF_DICDI Probable basic-leucine zipper tran...890.0002     47     30     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q8X229    399   FCR3_CANAX Fluconazole resistance protein 3 O...910.005     42.4     36     51GO:0005634; C:nucleus; IC:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5P19880    650   YAP1_YEAST AP-1-like transcription factor YAP...380.008     42     47     74GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:SGD.
GO:0061395; P:positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance; IMP:SGD.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IDA:SGD.::GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.::GO:0042493; P:response to drug; IMP:SGD.::GO:0009408; P:response to heat; IMP:SGD.::GO:0000304; P:response to singlet oxygen; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6P24813    409   YAP2_YEAST AP-1-like transcription activator ...390.011     41.2     46     74GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.
GO:0071276; P:cellular response to cadmium ion; IDA:SGD.::GO:0036003; P:positive regulation of transcription from RNA polymerase II promoter in response to stress; IGI:SGD.
7Q01663    552   AP1_SCHPO AP-1-like transcription factor OS=S...350.028     40     49     71GO:0005829; C:cytosol; IDA:PomBase.::GO:0035267; C:NuA4 histone acetyltransferase complex; IDA:PomBase.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; TAS:PomBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.
GO:0071313; P:cellular response to caffeine; IMP:PomBase.::GO:0070301; P:cellular response to hydrogen peroxide; IMP:PomBase.::GO:0006995; P:cellular response to nitrogen starvation; IEP:PomBase.::GO:0016573; P:histone acetylation; IC:PomBase.::GO:0051595; P:response to methylglyoxal; IMP:PomBase.
8P56095    583   AP1_KLULA AP-1-like transcription factor OS=1...270.031     40     59     81GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q96BA8    519   CR3L1_HUMAN Cyclic AMP-responsive element-bin...720.21     37.4     31     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10P38749    330   YAP3_YEAST AP-1-like transcription factor YAP...280.22     37     57     75GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IPI:SGD.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:SGD.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11P18850    670   ATF6A_HUMAN Cyclic AMP-dependent transcriptio...870.33     37     26     54GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0006990; P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; TAS:ProtInc.::GO:0006457; P:protein folding; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q54LU5    999   BZPN_DICDI Probable basic-leucine zipper tran...650.37     36.6     37     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q2UNX4    284   KAPC_ASPOR Putative transcription factor kapC...320.61     35.4     50     69GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q9DBS5    619   KLC4_MOUSE Kinesin light chain 4 OS=Mus muscu...670.82     35.4     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005871; C:kinesin complex; IEA:InterPro.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
15Q54T16    650   BZPK_DICDI Probable basic-leucine zipper tran...550.92     35.4     38     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16O35426    267   XBP1_MOUSE X-box-binding protein 1 OS=Mus mus...711.1     34.7     30     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0060691; P:epithelial cell maturation involved in salivary gland development; IMP:MGI.::GO:0031017; P:exocrine pancreas development; IMP:MGI.
17Q9Y2I6    1382   NINL_HUMAN Ninein-like protein OS=Homo sapien...1381.2     35     21     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
18Q7Z406    1995   MYH14_HUMAN Myosin-14 OS=Homo sapiens (Human)...921.4     35     28     53GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
19Q5TZA2    2017   CROCC_HUMAN Rootletin OS=Homo sapiens (Human)...1661.5     35     22     39GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005814; C:centriole; ISS:UniProtKB.::GO:0035253; C:ciliary rootlet; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0019894; F:kinesin binding; ISS:UniProtKB.::GO:0005198; F:structural molecule activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0051297; P:centrosome organization; IDA:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB.
20Q55E93    418   BZPE_DICDI Probable basic-leucine zipper tran...351.5     34.7     46     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21P52890    566   ATF1_SCHPO Transcription factor atf1 OS=Schiz...911.7     34.7     27     44GO:0000790; C:nuclear chromatin; NAS:PomBase.
GO:0046982; F:protein heterodimerization activity; IPI:PomBase.::GO:0042803; F:protein homodimerization activity; IPI:PomBase.::GO:0010844; F:recombination hotspot binding; IDA:PomBase.::GO:0003723; F:RNA binding; IDA:PomBase.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:PomBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.
GO:0010846; P:activation of reciprocal meiotic recombination; IMP:PomBase.::GO:0070301; P:cellular response to hydrogen peroxide; IGI:PomBase.::GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0000080; P:G1 phase of mitotic cell cycle; IMP:PomBase.::GO:0031990; P:mRNA export from nucleus in response to heat stress; IMP:PomBase.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:PomBase.::GO:0051039; P:positive regulation of transcription during meiosis; IDA:PomBase.::GO:0043949; P:regulation of cAMP-mediated signaling; IMP:PomBase.::GO:0010847; P:regulation of chromatin assembly; IMP:PomBase.::GO:0010848; P:regulation of chromatin disassembly; IMP:PomBase.::GO:0035065; P:regulation of histone acetylation; IMP:PomBase.::GO:0031060; P:regulation of histone methylation; IMP:PomBase.
22P0C5H8    278   KAPC_EMENI Putative transcription factor kapC...1001.8     33.9     35     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23Q3SZZ2    261   XBP1_BOVIN X-box-binding protein 1 OS=Bos tau...821.8     33.9     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q8N6L0    562   CC155_HUMAN Coiled-coil domain-containing pro...1732.1     34.3     24     41GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
25Q66HA2    520   CR3L1_RAT Cyclic AMP-responsive element-bindi...722.4     33.9     28     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q9Z125    519   CR3L1_MOUSE Cyclic AMP-responsive element-bin...722.5     33.9     28     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO:0030500; P:regulation of bone mineralization; IMP:MGI.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
27Q5PQM2    619   KLC4_RAT Kinesin light chain 4 OS=Rattus norv...652.6     33.9     29     54GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005871; C:kinesin complex; IEA:InterPro.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
28Q5DTU0    825   AF1L2_MOUSE Actin filament-associated protein...612.7     33.9     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
29Q2T9I5    1059   RBM26_XENLA RNA-binding protein 26 OS=Xenopus...1442.7     33.9     25     45
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
30Q9R1S4    267   XBP1_RAT X-box-binding protein 1 OS=Rattus no...713     33.1     30     49GO:0005634; C:nucleus; IDA:RGD.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0051602; P:response to electrical stimulus; IDA:RGD.::GO:0060096; P:serotonin secretion, neurotransmission; IDA:RGD.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:RGD.
31Q5SNZ0    1873   GRDN_MOUSE Girdin OS=Mus musculus (Mouse). GN...1243.3     33.9     27     44GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043422; F:protein kinase B binding; IPI:UniProtKB.
GO:0032148; P:activation of protein kinase B activity; IDA:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0016044; P:cellular membrane organization; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.::GO:0006275; P:regulation of DNA replication; IMP:UniProtKB.::GO:0010975; P:regulation of neuron projection development; IDA:UniProtKB.::GO:0031929; P:TOR signaling cascade; IDA:UniProtKB.
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