Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR253C
Length:
191
Number of sequences:
5887
Description:
YDR253C MET32 SGDID:S000002661, Chr IV from 964565-963990, Genome Release 64-1-1, reverse complement, Verified ORF, "Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met31p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481P08154    508   EGR1_RAT Early growth response protein 1 OS=R...320.26     35.4     47     59GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:RGD.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:RGD.::GO:0008134; F:transcription factor binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0035690; P:cellular response to drug; IEP:RGD.::GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0071504; P:cellular response to heparin; IDA:UniProtKB.::GO:0071455; P:cellular response to hyperoxia; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071317; P:cellular response to isoquinoline alkaloid; IEP:RGD.::GO:0071260; P:cellular response to mechanical stimulus; IEP:RGD.::GO:0071506; P:cellular response to mycophenolic acid; IDA:UniProtKB.::GO:0071383; P:cellular response to steroid hormone stimulus; IEP:RGD.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0072110; P:glomerular mesangial cell proliferation; IMP:UniProtKB.::GO:0007611; P:learning or memory; IMP:RGD.::GO:0060291; P:long-term synaptic potentiation; IEP:RGD.::GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; IMP:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:RGD.::GO:0001975; P:response to amphetamine; IEP:RGD.::GO:0034465; P:response to carbon monoxide; IEP:RGD.::GO:0042220; P:response to cocaine; IEP:RGD.::GO:0051602; P:response to electrical stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0071873; P:response to norepinephrine stimulus; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.
482B7ZSG3    414   WT1A_XENLA Wilms tumor protein homolog A OS=X...620.000004     49.7     44     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0072013; P:glomus development; IMP:UniProtKB.::GO:1900207; P:negative regulation of pronephric nephron tubule development; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IGI:UniProtKB.::GO:0039004; P:specification of pronephric proximal tubule identity; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
483Q8BLB0    497   ZFP3_MOUSE Zinc finger protein 3 OS=Mus muscu...320.31     35     50     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
484Q9UK12    451   ZN222_HUMAN Zinc finger protein 222 OS=Homo s...527.5     30.8     35     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
485P18723    647   ZG48_XENLA Gastrula zinc finger protein XlCGF...342.1     32.7     44     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
486Q9Y3M9    751   ZN337_HUMAN Zinc finger protein 337 OS=Homo s...594.2     31.6     31     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
487P18741    140   ZO15_XENLA Oocyte zinc finger protein XlCOF15...520.0002     43.1     40     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
488Q8BGS3    561   ZKSC1_MOUSE Zinc finger protein with KRAB and...320.57     34.3     50     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
489P08152    470   EGR2_MOUSE E3 SUMO-protein ligase EGR2 OS=Mus...570.14     36.2     37     47GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035284; P:brain segmentation; IMP:MGI.::GO:0071310; P:cellular response to organic substance; IDA:MGI.::GO:0021612; P:facial nerve structural organization; IGI:MGI.::GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0042552; P:myelination; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006611; P:protein export from nucleus; IDA:UniProtKB.::GO:0030278; P:regulation of ossification; IMP:MGI.::GO:0021660; P:rhombomere 3 formation; IMP:MGI.::GO:0021666; P:rhombomere 5 formation; IMP:MGI.::GO:0007622; P:rhythmic behavior; IDA:MGI.::GO:0014037; P:Schwann cell differentiation; IMP:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
490Q14584    549   ZN266_HUMAN Zinc finger protein 266 OS=Homo s...602.1     32.7     35     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
491P53035    382   MIG2_YEAST Regulatory protein MIG2 OS=Sacchar...780.000003     50.1     38     49GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IDA:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
492P51774    470   EGR2_RAT E3 SUMO-protein ligase EGR2 OS=Rattu...570.14     36.2     37     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007611; P:learning or memory; IEP:RGD.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IMP:RGD.
493A1XSY8    471   EGR2_PIG E3 SUMO-protein ligase EGR2 OS=Sus s...570.14     36.2     37     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006611; P:protein export from nucleus; ISS:UniProtKB.
494Q6ZN11    374   ZN793_HUMAN Zinc finger protein 793 OS=Homo s...340.29     35     41     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
495Q68DY9    489   ZN772_HUMAN Zinc finger protein 772 OS=Homo s...946.4     31.2     28     44GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
496Q9UK11    482   ZN223_HUMAN Zinc finger protein 223 OS=Homo s...510.83     33.9     31     45GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
497Q86XU0    584   ZN677_HUMAN Zinc finger protein 677 OS=Homo s...340.32     35     41     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
498O43345    1167   ZN208_HUMAN Zinc finger protein 208 OS=Homo s...348.3     30.8     44     59GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
499P35789    620   ZNF93_HUMAN Zinc finger protein 93 OS=Homo sa...990.008     40     30     40GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
500P18146    543   EGR1_HUMAN Early growth response protein 1 OS...310.25     35.4     48     61GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0035035; F:histone acetyltransferase binding; IPI:BHF-UCL.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.::GO:0072110; P:glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0033233; P:regulation of protein sumoylation; IDA:BHF-UCL.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
501Q4KLI1    562   ZKSC1_RAT Zinc finger protein with KRAB and S...320.57     34.3     50     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
502P08046    533   EGR1_MOUSE Early growth response protein 1 OS...310.26     35.4     48     61GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030509; P:BMP signaling pathway; IDA:MGI.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.::GO:0072110; P:glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0032868; P:response to insulin stimulus; IDA:UniProtKB.::GO:0030217; P:T cell differentiation; IMP:MGI.
503B2KFW1    1030   ZSC20_MOUSE Zinc finger and SCAN domain-conta...320.65     34.3     44     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
504A3KN32    543   ZNF34_BOVIN Zinc finger protein 34 OS=Bos tau...350.4     34.7     40     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
505Q9US36    781   YFZ5_SCHPO Zinc finger protein C1039.05c OS=S...740.000003     50.1     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005819; C:spindle; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
506P11161    476   EGR2_HUMAN E3 SUMO-protein ligase EGR2 OS=Hom...570.14     36.2     37     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:BHF-UCL.
507P18743    157   ZO2_XENLA Oocyte zinc finger protein XlCOF2 O...720.51     33.9     32     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
508Q9Y2Q1    563   ZN257_HUMAN Zinc finger protein 257 OS=Homo s...1122.1     32.7     26     40GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
509P17029    563   ZKSC1_HUMAN Zinc finger protein with KRAB and...320.71     33.9     50     59GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
510Q8BXX2    756   ZBT49_MOUSE Zinc finger and BTB domain-contai...740.15     36.2     30     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
511Q62396    488   ZFP92_MOUSE Zinc finger protein 92 OS=Mus mus...585.8     31.2     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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