Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR247W
Length:
461
Number of sequences:
5887
Description:
YDR247W VHS1 SGDID:S000002655, Chr IV from 956013-957398, Genome Release 64-1-1, Verified ORF, "Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151P25389    1037   KCC4_YEAST Probable serine/threonine-protein ...2213e-16     85.1     27     49GO:0032174; C:cellular bud neck septin collar; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005940; C:septin ring; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007117; P:budding cell bud growth; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0000135; P:septin checkpoint; IGI:SGD.::GO:0000921; P:septin ring assembly; IMP:SGD.
152Q60EY8    466   CIPKK_ORYSJ CBL-interacting protein kinase 20...2393e-16     84.3     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
153Q94C40    432   CIPKH_ARATH CBL-interacting serine/threonine-...3313e-16     84     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
154Q9NRH2    765   SNRK_HUMAN SNF-related serine/threonine-prote...2634e-16     84.7     29     49GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB.
155Q8RWC9    444   CIPK1_ARATH CBL-interacting serine/threonine-...2214e-16     84     29     49GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
156Q41639    294   CDC2_VIGAC Cell division control protein 2 ho...2955e-16     82     25     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
157Q8BZN4    639   NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS...2825e-16     84.3     30     44
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
158Q76P07    833   Y7165_DICDI Probable serine/threonine-protein...2485e-16     84.3     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030587; P:sorocarp development; IMP:dictyBase.
159P24100    294   CDKA1_ARATH Cyclin-dependent kinase A-1 OS=Ar...3365e-16     81.6     25     39GO:0010005; C:cortical microtubule, transverse to long axis; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009574; C:preprophase band; TAS:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0000910; P:cytokinesis; IMP:TAIR.::GO:0042023; P:DNA endoreduplication; IMP:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0008284; P:positive regulation of cell proliferation; IMP:TAIR.::GO:0040020; P:regulation of meiosis; IMP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.
160Q66HE5    630   NUAK2_RAT NUAK family SNF1-like kinase 2 OS=R...2615e-16     84     30     46
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
161P93101    294   CDC2_CHERU Cell division control protein 2 ho...2346e-16     81.6     27     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
162Q39030    471   KPK2_ARATH Serine/threonine-protein kinase At...3166e-16     83.6     25     42GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045727; P:positive regulation of translation; TAS:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
163P00546    298   CDK1_YEAST Cyclin-dependent kinase 1 OS=Sacch...3528e-16     81.3     26     39GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:SGD.::GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0042393; F:histone binding; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051447; P:negative regulation of meiotic cell cycle; IMP:SGD.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:SGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:SGD.::GO:0010571; P:positive regulation of DNA replication involved in S phase; IMP:SGD.::GO:0051446; P:positive regulation of meiotic cell cycle; IDA:SGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:SGD.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:SGD.::GO:0010898; P:positive regulation of triglyceride catabolic process; IMP:SGD.::GO:0010568; P:regulation of budding cell apical bud growth; IMP:SGD.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:SGD.::GO:0010570; P:regulation of filamentous growth; IMP:SGD.
164Q9SIQ7    582   CDPKO_ARATH Calcium-dependent protein kinase ...3279e-16     83.2     24     42GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
165Q05006    294   CDC22_MEDSA Cell division control protein 2 h...3029e-16     81.3     25     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
166A1A5Q6    654   SMK_RAT Sperm motility kinase OS=Rattus norve...2179e-16     83.6     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
167P45894    589   AAPK1_CAEEL 5'-AMP-activated protein kinase c...3250.000000000000001     83.2     27     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.
168Q8ICR0    509   CDPK2_PLAF7 Calcium-dependent protein kinase ...3450.000000000000001     82.8     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:GeneDB_Pfalciparum.
169P42818    465   KPK1_ARATH Serine/threonine-protein kinase At...3160.000000000000001     82.8     24     42GO:0005737; C:cytoplasm; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0045727; P:positive regulation of translation; TAS:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
170Q96PY6    1258   NEK1_HUMAN Serine/threonine-protein kinase Ne...3240.000000000000001     83.6     26     41GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
171Q9H093    628   NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS...2660.000000000000001     83.2     29     46
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
172Q5R7G9    628   NUAK2_PONAB NUAK family SNF1-like kinase 2 OS...2660.000000000000001     83.2     29     46
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
173Q6NW76    320   AURKB_DANRE Aurora kinase B OS=Danio rerio (Z...2230.000000000000001     80.9     28     45GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007059; P:chromosome segregation; IMP:ZFIN.::GO:0000910; P:cytokinesis; IMP:ZFIN.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
174P0C8M8    626   CCR1_MAIZE Probable serine/threonine-protein ...2600.000000000000001     82.8     29     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
175O15865    513   CDPK2_PLAFK Calcium-dependent protein kinase ...3450.000000000000001     82.4     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
176Q69ZM6    1316   STK36_MOUSE Serine/threonine-protein kinase 3...4040.000000000000002     83.2     24     41GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.
GO:0042384; P:cilium assembly; IDA:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:UniProtKB.
177O70126    345   AURKB_MOUSE Aurora kinase B OS=Mus musculus (...3190.000000000000002     80.9     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
178P28583    508   CDPK_SOYBN Calcium-dependent protein kinase S...2540.000000000000002     82.4     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
179Q38772    294   CDC2A_ANTMA Cell division control protein 2 h...2340.000000000000002     80.1     28     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
180O88445    282   AURKC_MOUSE Aurora kinase C OS=Mus musculus (...2220.000000000000002     80.1     27     45GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
181Q63686    496   CDK16_RAT Cyclin-dependent kinase 16 OS=Rattu...2850.000000000000002     82     27     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
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