Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR234W
Length:
693
Number of sequences:
5887
Description:
YDR234W LYS4 SGDID:S000002642, Chr IV from 931129-933210, Genome Release 64-1-1, Verified ORF, "Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P49367    693   LYS4_YEAST Homoaconitase, mitochondrial OS=Sa...6930     1430     100     100GO:0005739; C:mitochondrion; IDA:SGD.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0019878; P:lysine biosynthetic process via aminoadipic acid; NAS:SGD.
2Q6CT61    693   LYS4_KLULA Homoaconitase, mitochondrial OS=12...6870     1146     80     89GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
3Q6FM51    689   LYS4_CANGA Homoaconitase, mitochondrial OS=NR...6850     1088     78     86GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
4Q5A644    684   LYS4_CANAL Homoaconitase, mitochondrial OS=Ca...6970     981     70     82GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
5Q2HZ33    688   LYS4_CANPA Homoaconitase, mitochondrial OS=Ca...6970     977     70     80GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
6Q6BM98    688   LYS4_DEBHA Homoaconitase, mitochondrial OS=00...6890     974     69     81GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
7Q6C791    687   LYS4_YARLI Homoaconitase, mitochondrial OS=li...6910     974     70     80GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
8Q75DX9    686   LYS4_ASHGO Homoaconitase, mitochondrial OS=Y-...6920     898     66     79GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
9Q9UT74    721   LYS4_SCHPO Homoaconitase, mitochondrial OS=Sc...6730     835     64     77GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IMP:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0006536; P:glutamate metabolic process; NAS:PomBase.::GO:0019878; P:lysine biosynthetic process via aminoadipic acid; IMP:PomBase.
10Q92412    776   LYS4_EMENI Homoaconitase, mitochondrial OS=19...7180     823     59     71GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
11Q870W1    784   LYS4_NEUCR Homoaconitase, mitochondrial OS=12...7210     818     59     71GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
12Q2U9G3    775   LYS4_ASPOR Homoaconitase, mitochondrial OS=As...7330     809     59     71GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
13Q58FL6    769   LYS4_ASPNC Homoaconitase, mitochondrial OS=As...7390     808     57     70GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
14Q2GN26    797   LYS4_CHAGB Homoaconitase, mitochondrial OS=63...7210     805     57     70GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
15Q4HVQ9    776   LYS4_GIBZE Homoaconitase, mitochondrial OS=(W...7080     804     58     71GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
16Q4WUL6    777   LYS4_ASPFU Homoaconitase, mitochondrial OS=A1...7050     780     57     72GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
17P0CM02    728   LYS4_CRYNJ Homoaconitase, mitochondrial OS=AT...7130     689     54     66GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
18P0CM03    728   LYS4_CRYNB Homoaconitase, mitochondrial OS=(F...7130     688     54     66GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
19Q4P521    698   LYS4_USTMA Homoaconitase, mitochondrial OS=Us...7010     678     54     65GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0004409; F:homoaconitate hydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
20Q6L0K5    413   LEUC_PICTO 3-isopropylmalate dehydratase larg...4311e-77     261     35     56
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
21B4U7U5    424   LEUC_HYDS0 3-isopropylmalate dehydratase larg...4522e-74     252     36     54
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
22O67078    432   LEUC_AQUAE 3-isopropylmalate dehydratase larg...4516e-74     251     35     53
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
23Q8U2A1    424   LEUC1_PYRFU 3-isopropylmalate dehydratase lar...4542e-72     247     34     52
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
24Q9WYC7    418   LEUC1_THEMA 3-isopropylmalate dehydratase lar...4498e-72     245     34     53
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
25Q9UZ07    423   LEUC1_PYRAB 3-isopropylmalate dehydratase lar...4511e-71     245     33     53
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:HAMAP.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:HAMAP.
26O27668    428   LEUC2_METTH 3-isopropylmalate dehydratase lar...4503e-71     244     33     53
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
27Q0QLE2    420   DMDA_EUBBA 2,3-dimethylmalate dehydratase lar...4506e-71     243     34     53
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:InterPro.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0047868; F:dimethylmaleate hydratase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051187; P:cofactor catabolic process; IDA:UniProtKB.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
28B2V844    431   LEUC_SULSY 3-isopropylmalate dehydratase larg...4571e-70     242     35     54
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
29Q30WD3    418   LEUC_DESDG 3-isopropylmalate dehydratase larg...4461e-70     242     35     54
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
30O28084    416   LEUC2_ARCFU 3-isopropylmalate dehydratase lar...4281e-70     241     37     55
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
31B2KBD7    418   LEUC_ELUMP 3-isopropylmalate dehydratase larg...4481e-70     241     33     53
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
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