Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR234W
Length:
693
Number of sequences:
5887
Description:
YDR234W LYS4 SGDID:S000002642, Chr IV from 931129-933210, Genome Release 64-1-1, Verified ORF, "Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
631Q01059    889   ACOC_RABIT Cytoplasmic aconitate hydratase OS...1061.9     35.4     31     52
GO:0051539; F:4 iron, 4 sulfur cluster binding; ISS:UniProtKB.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0030350; F:iron-responsive element binding; ISS:UniProtKB.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006101; P:citrate metabolic process; ISS:UniProtKB.::GO:0010040; P:response to iron(II) ion; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
632Q0VCU1    889   ACOC_BOVIN Cytoplasmic aconitate hydratase OS...515.4     33.9     35     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; ISS:UniProtKB.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0030350; F:iron-responsive element binding; ISS:UniProtKB.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006101; P:citrate metabolic process; ISS:UniProtKB.::GO:0010040; P:response to iron(II) ion; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
633C1CVE0    181   LEUD_DEIDV 3-isopropylmalate dehydratase smal...1056e-20     93.2     42     63GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
634B8J4G0    165   LEUD_DESDA 3-isopropylmalate dehydratase smal...1721e-19     91.3     33     52GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
635Q9RTI0    208   LEUD2_DEIRA 3-isopropylmalate dehydratase sma...1191e-19     92.4     40     61GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
636Q9I3F5    910   ACON1_PSEAE Aconitate hydratase 1 OS=12228). ...660.99     36.6     35     52
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
637Q90875    889   ACOC_CHICK Cytoplasmic aconitate hydratase OS...5462e-19     96.7     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
638Q63270    889   ACOC_RAT Cytoplasmic aconitate hydratase OS=R...5013e-19     96.7     25     40GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005792; C:microsome; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051539; F:4 iron, 4 sulfur cluster binding; ISS:UniProtKB.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0030350; F:iron-responsive element binding; ISS:UniProtKB.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0048027; F:mRNA 5'-UTR binding; IDA:RGD.
GO:0006879; P:cellular iron ion homeostasis; IDA:RGD.::GO:0006101; P:citrate metabolic process; ISS:UniProtKB.::GO:0006417; P:regulation of translation; TAS:RGD.::GO:0010040; P:response to iron(II) ion; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
639B0TCR3    166   LEUD_HELMI 3-isopropylmalate dehydratase smal...1893e-19     90.5     33     48GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
640Q42669    764   ACOC_CUCMC Aconitate hydratase OS=Cucumis mel...640.65     37     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.
641Q2LWJ1    164   LEUD_SYNAS 3-isopropylmalate dehydratase smal...1644e-19     90.1     36     52GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
642C3NMW1    165   LEUD_SULIN 3-isopropylmalate dehydratase smal...1744e-19     90.1     36     50GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
643Q8FTA8    937   ACON_COREF Aconitate hydratase OS=11189 / NBR...530.48     37.4     36     57
GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
644P28271    889   ACOC_MOUSE Cytoplasmic aconitate hydratase OS...883.3     34.7     32     51GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0051539; F:4 iron, 4 sulfur cluster binding; ISS:UniProtKB.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0030350; F:iron-responsive element binding; ISS:UniProtKB.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0006101; P:citrate metabolic process; ISS:UniProtKB.::GO:0050892; P:intestinal absorption; IGI:MGI.::GO:0009791; P:post-embryonic development; IGI:MGI.::GO:0006417; P:regulation of translation; IMP:MGI.::GO:0010040; P:response to iron(II) ion; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
645Q4JVM4    936   ACON_CORJK Aconitate hydratase OS=Corynebacte...930.11     39.7     33     48
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
646Q8TX94    170   LEUD1_METKA 3-isopropylmalate dehydratase sma...1305e-19     90.1     42     55GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
647P09339    909   ACON_BACSU Aconitate hydratase OS=Bacillus su...662.5     35     35     53
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
648Q97EE1    163   LEUD_CLOAB 3-isopropylmalate dehydratase smal...1007e-19     89.4     49     62GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
649Q8TRF7    164   LEUD3_METAC 3-isopropylmalate dehydratase sma...967e-19     89.4     50     59GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
650Q0QLE1    163   DMDB_EUBBA 2,3-dimethylmalate dehydratase sma...1018e-19     89.4     46     64GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:InterPro.::GO:0047868; F:dimethylmaleate hydratase activity; IDA:UniProtKB.
GO:0051187; P:cofactor catabolic process; IDA:UniProtKB.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
651Q4JC10    161   LEUD_SULAC 3-isopropylmalate dehydratase smal...1748e-19     89.4     39     53GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
652Q8U0B9    164   LEUD2_PYRFU 3-isopropylmalate dehydratase sma...1268e-19     89.4     44     56GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
653Q58673    168   LEUD_METJA Isopropylmalate/citramalate isomer...1739e-19     89.4     36     51GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0047508; F:(R)-2-methylmalate dehydratase activity; IEA:EC.::GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0050075; F:maleate hydratase activity; IEA:EC.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
654Q5JFV7    163   LEUD_PYRKO 3-isopropylmalate dehydratase smal...1209e-19     89     42     57GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
655B8CX23    165   LEUD_HALOH 3-isopropylmalate dehydratase smal...1109e-19     89     42     64GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
656Q8NQ98    939   ACON_CORGL Aconitate hydratase OS=LMG 3730 / ...840.087     40     31     48
GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
657Q9RTN7    906   ACON_DEIRA Aconitate hydratase OS=LMG 4051 / ...513.7     34.7     33     57
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
658B3VKQ2    964   IREB2_PIG Iron-responsive element-binding pro...4062e-18     94     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0008152; P:metabolic process; IEA:InterPro.
659B9MLV3    166   LEUD_ANATD 3-isopropylmalate dehydratase smal...952e-18     88.2     49     65GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
660A9KT78    165   LEUD_CLOPH 3-isopropylmalate dehydratase smal...962e-18     88.2     48     66GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
661C3N1A2    165   LEUD_SULIA 3-isopropylmalate dehydratase smal...1742e-18     87.8     37     50GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
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