UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR234W

Length:

693

Number of sequences:

5887

Description:

YDR234W LYS4 SGDID:S000002642, Chr IV from 931129-933210, Genome Release 64-1-1, Verified ORF, "Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
571	Q64QP1	464	LEUC_BACFR 3-isopropylmalate dehydratase larg...	452	1e-28	123	25	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
572	Q5LAB1	464	LEUC_BACFN 3-isopropylmalate dehydratase larg...	452	1e-28	123	25	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
573	B1ZUZ1	472	LEUC_OPITP 3-isopropylmalate dehydratase larg...	462	1e-28	123	26	40
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
574	B8J825	480	LEUC_ANAD2 3-isopropylmalate dehydratase larg...	460	2e-28	122	27	43
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
575	Q3J716	469	LEUC_NITOC 3-isopropylmalate dehydratase larg...	373	2e-28	122	29	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
576	A4VKE7	475	LEUC_PSEU5 3-isopropylmalate dehydratase larg...	384	2e-28	122	28	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
577	Q2NVW5	466	LEUC_SODGM 3-isopropylmalate dehydratase larg...	435	3e-28	122	26	42
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
578	Q21IY3	472	LEUC_SACD2 3-isopropylmalate dehydratase larg...	441	3e-28	122	25	42
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
579	B4RM67	469	LEUC_NEIG2 3-isopropylmalate dehydratase larg...	450	4e-28	122	25	43
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
580	Q7U9J4	472	LEUC_SYNPX 3-isopropylmalate dehydratase larg...	444	4e-28	121	27	43
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
581	Q3BPJ6	482	LEUC_XANC5 3-isopropylmalate dehydratase larg...	375	5e-28	121	28	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
582	Q8A6L7	464	LEUC_BACTN 3-isopropylmalate dehydratase larg...	450	7e-28	120	25	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
583	Q5F8T1	469	LEUC_NEIG1 3-isopropylmalate dehydratase larg...	450	8e-28	120	25	43
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
584	P58948	479	LEUC_XANAC 3-isopropylmalate dehydratase larg...	377	1e-27	120	29	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
585	Q9ZND5	472	LEUC_THET8 3-isopropylmalate dehydratase larg...	495	1e-27	120	27	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
586	Q72JB3	472	LEUC_THET2 3-isopropylmalate dehydratase larg...	495	1e-27	120	27	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
587	Q04DA3	457	LEUC_OENOB 3-isopropylmalate dehydratase larg...	413	4e-27	118	26	41
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
588	P34455	777	ACON_CAEEL Probable aconitate hydratase, mito...	466	5e-27	120	27	47	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
589	Q9EVE0	444	LEUC_BUCUD 3-isopropylmalate dehydratase larg...	424	6e-27	118	25	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
590	Q2IJC2	480	LEUC_ANADE 3-isopropylmalate dehydratase larg...	460	6e-27	118	26	42
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
591	B3PFN2	473	LEUC_CELJU 3-isopropylmalate dehydratase larg...	427	7e-27	118	26	42
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
592	A6L1V8	460	LEUC_BACV8 3-isopropylmalate dehydratase larg...	482	1e-26	117	24	42
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
593	A6VX34	475	LEUC_MARMS 3-isopropylmalate dehydratase larg...	437	1e-26	117	26	42
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
594	Q47HR4	468	LEUC_DECAR 3-isopropylmalate dehydratase larg...	436	3e-26	116	27	42
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
595	Q94A28	995	ACO3M_ARATH Aconitate hydratase 3, mitochondr...	64	2.9	35	33	53	GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005829; C:cytosol; NAS:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0005507; F:copper ion binding; IDA:TAIR.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.
									GO:0006101; P:citrate metabolic process; IMP:TAIR.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IMP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IMP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
596	Q1RKD5	885	ACON_RICBR Aconitate hydratase OS=Rickettsia ...	434	4e-25	115	26	45
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
597	P63434	901	ACON_STAAW Aconitate hydratase OS=Staphylococ...	70	3.2	34.7	31	51
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
598	Q6G9K9	901	ACON_STAAS Aconitate hydratase OS=Staphylococ...	70	3.2	34.7	31	51
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
599	P99148	901	ACON_STAAN Aconitate hydratase OS=Staphylococ...	70	3.2	34.7	31	51
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
600	P63433	901	ACON_STAAM Aconitate hydratase OS=Staphylococ...	70	3.2	34.7	31	51
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
601	Q5HG69	901	ACON_STAAC Aconitate hydratase OS=Staphylococ...	70	3.2	34.7	31	51
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.

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