UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR234W

Length:

693

Number of sequences:

5887

Description:

YDR234W LYS4 SGDID:S000002642, Chr IV from 931129-933210, Genome Release 64-1-1, Verified ORF, "Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
451	Q03KB3	460	LEUC_STRTD 3-isopropylmalate dehydratase larg...	424	5e-33	136	27	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
452	A7MWC3	466	LEUC_VIBHB 3-isopropylmalate dehydratase larg...	472	5e-33	136	25	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
453	Q0BAC8	469	LEUC_BURCM 3-isopropylmalate dehydratase larg...	375	6e-33	136	29	48
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
454	B1Z1N0	469	LEUC_BURA4 3-isopropylmalate dehydratase larg...	375	6e-33	136	29	48
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
455	Q07UU3	470	LEUC_RHOP5 3-isopropylmalate dehydratase larg...	436	6e-33	136	25	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
456	Q9AQC6	369	LEUC_BUCUL 3-isopropylmalate dehydratase larg...	348	6e-33	134	29	47
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
457	Q28W60	468	LEUC_JANSC 3-isopropylmalate dehydratase larg...	458	6e-33	136	25	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
458	A1WAS7	473	LEUC_ACISJ 3-isopropylmalate dehydratase larg...	486	6e-33	136	28	42
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
459	B4RVU9	466	LEUC_ALTMD 3-isopropylmalate dehydratase larg...	442	7e-33	136	27	43
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
460	Q3M614	467	LEUC_ANAVT 3-isopropylmalate dehydratase larg...	456	7e-33	136	26	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
461	Q5LZF4	460	LEUC_STRT1 3-isopropylmalate dehydratase larg...	434	7e-33	135	28	47
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
462	Q7MP79	466	LEUC_VIBVY 3-isopropylmalate dehydratase larg...	472	9e-33	135	26	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
463	Q393X2	469	LEUC_BURS3 3-isopropylmalate dehydratase larg...	375	9e-33	135	29	48
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
464	Q4ZUZ6	474	LEUC_PSEU2 3-isopropylmalate dehydratase larg...	453	1e-32	135	28	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
465	Q8XXX3	469	LEUC_RALSO 3-isopropylmalate dehydratase larg...	365	1e-32	135	27	47
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
466	B8HLN1	468	LEUC_CYAP4 3-isopropylmalate dehydratase larg...	450	1e-32	135	26	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
467	Q9EVG5	443	LEUC_BUCUA 3-isopropylmalate dehydratase larg...	427	1e-32	135	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
468	Q1H0L4	468	LEUC_METFK 3-isopropylmalate dehydratase larg...	491	1e-32	135	25	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
469	A1SVE7	465	LEUC_PSYIN 3-isopropylmalate dehydratase larg...	466	1e-32	135	26	43
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
470	A5GIG7	472	LEUC_SYNPW 3-isopropylmalate dehydratase larg...	443	1e-32	135	27	43
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
471	Q6AFK7	486	LEUC_LEIXX 3-isopropylmalate dehydratase larg...	448	2e-32	135	25	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
472	P82611	777	ACON_CANAL Aconitate hydratase, mitochondrial...	459	2e-32	138	26	46	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:CGD.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0044416; P:induction by symbiont of host defense response; IDA:CGD.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
473	Q1ICW0	477	LEUC_PSEE4 3-isopropylmalate dehydratase larg...	463	2e-32	135	27	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
474	Q48K99	474	LEUC_PSE14 3-isopropylmalate dehydratase larg...	453	2e-32	135	28	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
475	B5FGH2	471	LEUC_VIBFM 3-isopropylmalate dehydratase larg...	437	2e-32	135	26	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
476	A6V2V3	474	LEUC_PSEA7 3-isopropylmalate dehydratase larg...	385	2e-32	134	29	48
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
477	Q11NN8	466	LEUC_CYTH3 3-isopropylmalate dehydratase larg...	453	2e-32	134	26	43
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
478	Q9HZA3	474	LEUC_PSEAE 3-isopropylmalate dehydratase larg...	385	2e-32	134	29	48
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
479	Q02PT4	474	LEUC_PSEAB 3-isopropylmalate dehydratase larg...	385	2e-32	134	29	48
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
480	B7VBP9	474	LEUC_PSEA8 3-isopropylmalate dehydratase larg...	385	2e-32	134	29	48
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
481	B2UPW8	470	LEUC_AKKM8 3-isopropylmalate dehydratase larg...	489	3e-32	134	26	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.

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