UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR234W

Length:

693

Number of sequences:

5887

Description:

YDR234W LYS4 SGDID:S000002642, Chr IV from 931129-933210, Genome Release 64-1-1, Verified ORF, "Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
211	A5IUK5	456	LEUC_STAA9 3-isopropylmalate dehydratase larg...	446	3e-39	154	30	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
212	Q2FWK1	456	LEUC_STAA8 3-isopropylmalate dehydratase larg...	446	3e-39	154	30	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
213	Q2FF65	456	LEUC_STAA3 3-isopropylmalate dehydratase larg...	446	3e-39	154	30	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
214	A6U3E4	456	LEUC_STAA2 3-isopropylmalate dehydratase larg...	446	3e-39	154	30	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
215	A7X4N3	456	LEUC_STAA1 3-isopropylmalate dehydratase larg...	446	3e-39	154	30	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
216	O53237	473	LEUC_MYCTU 3-isopropylmalate dehydratase larg...	451	4e-39	154	27	45	GO:0005618; C:cell wall; IDA:MTBBASE.
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
217	A5U6Z9	473	LEUC_MYCTA 3-isopropylmalate dehydratase larg...	451	4e-39	154	27	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
218	Q4L7U2	456	LEUC_STAHJ 3-isopropylmalate dehydratase larg...	443	5e-39	154	31	47
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
219	A4X4C8	481	LEUC_SALTO 3-isopropylmalate dehydratase larg...	500	5e-39	154	25	44
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
220	P19414	778	ACON_YEAST Aconitate hydratase, mitochondrial...	459	5e-39	157	29	47	GO:0005829; C:cytosol; IDA:SGD.::GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome.::GO:0042645; C:mitochondrial nucleoid; IDA:SGD.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0003690; F:double-stranded DNA binding; IDA:SGD.::GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IDA:SGD.
									GO:0006101; P:citrate metabolic process; TAS:SGD.::GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0000002; P:mitochondrial genome maintenance; IMP:SGD.::GO:0019541; P:propionate metabolic process; IEP:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD.
221	Q7ZAG7	473	LEUC_HALVD 3-isopropylmalate dehydratase larg...	448	6e-39	154	27	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
222	B8E4K6	468	LEUC_SHEB2 3-isopropylmalate dehydratase larg...	473	7e-39	153	27	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
223	A7HT10	473	LEUC_PARL1 3-isopropylmalate dehydratase larg...	453	7e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
224	Q8YJC9	469	LEUC_BRUME 3-isopropylmalate dehydratase larg...	435	8e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
225	C0RFF1	469	LEUC_BRUMB 3-isopropylmalate dehydratase larg...	435	8e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
226	Q65VS0	475	LEUC1_MANSM 3-isopropylmalate dehydratase lar...	371	8e-39	153	32	49
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
227	Q8FYG9	469	LEUC_BRUSU 3-isopropylmalate dehydratase larg...	435	9e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
228	B0CIF7	469	LEUC_BRUSI 3-isopropylmalate dehydratase larg...	435	9e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
229	A5VSN3	469	LEUC_BRUO2 3-isopropylmalate dehydratase larg...	435	9e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
230	A9M8P2	469	LEUC_BRUC2 3-isopropylmalate dehydratase larg...	435	9e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
231	Q57AZ0	469	LEUC_BRUAB 3-isopropylmalate dehydratase larg...	435	9e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
232	Q2YLP7	469	LEUC_BRUA2 3-isopropylmalate dehydratase larg...	435	9e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
233	B2S860	469	LEUC_BRUA1 3-isopropylmalate dehydratase larg...	435	9e-39	153	26	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
234	Q11CQ6	469	LEUC_MESSB 3-isopropylmalate dehydratase larg...	441	9e-39	153	27	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
235	Q49Z14	456	LEUC_STAS1 3-isopropylmalate dehydratase larg...	443	1e-38	152	30	46
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
236	A1REY2	474	LEUC_SHESW 3-isopropylmalate dehydratase larg...	476	1e-38	152	26	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
237	C1AGA3	473	LEUC_MYCBT 3-isopropylmalate dehydratase larg...	451	1e-38	152	27	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
238	A1KMY2	473	LEUC_MYCBP 3-isopropylmalate dehydratase larg...	451	1e-38	152	27	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
239	Q7TXH6	473	LEUC_MYCBO 3-isopropylmalate dehydratase larg...	451	1e-38	152	27	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
240	A9KY15	468	LEUC_SHEB9 3-isopropylmalate dehydratase larg...	473	1e-38	152	27	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
241	A6WIB7	468	LEUC_SHEB8 3-isopropylmalate dehydratase larg...	473	1e-38	152	27	45
									GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:EC.::GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.

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