UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR232W

Length:

548

Number of sequences:

5887

Description:

YDR232W HEM1 SGDID:S000002640, Chr IV from 927452-929098, Genome Release 64-1-1, Verified ORF, "5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
331	B1X7A6	384	BIOF_ECODH 8-amino-7-oxononanoate synthase OS...	358	1e-28	120	28	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
332	Q0BBD6	471	BIOF_BURCM 8-amino-7-oxononanoate synthase OS...	451	1e-28	122	29	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
333	B4E9L6	394	BIOF_BURCJ 8-amino-7-oxononanoate synthase OS...	410	1e-28	120	29	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
334	B7M748	384	BIOF_ECO8A 8-amino-7-oxononanoate synthase OS...	358	3e-28	119	28	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
335	A8AJ11	384	BIOF_CITK8 8-amino-7-oxononanoate synthase OS...	411	4e-28	119	27	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
336	A0QX65	382	BIKB_MYCS2 Putative 8-amino-7-oxononanoate sy...	413	1e-27	118	30	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
337	A4T9L3	380	BIKB_MYCGI Putative 8-amino-7-oxononanoate sy...	368	2e-27	117	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
338	Q66D66	383	BIOF_YERPS 8-amino-7-oxononanoate synthase OS...	413	2e-27	117	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
339	B2K8T1	383	BIOF_YERPB 8-amino-7-oxononanoate synthase OS...	413	2e-27	117	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
340	A4TNQ5	383	BIOF_YERPP 8-amino-7-oxononanoate synthase OS...	413	3e-27	117	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
341	Q1CFQ4	383	BIOF_YERPN 8-amino-7-oxononanoate synthase OS...	413	3e-27	117	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
342	A9R3C9	383	BIOF_YERPG 8-amino-7-oxononanoate synthase OS...	413	3e-27	117	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
343	Q7CH66	383	BIOF_YERPE 8-amino-7-oxononanoate synthase OS...	413	3e-27	117	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
344	Q1C946	383	BIOF_YERPA 8-amino-7-oxononanoate synthase OS...	413	3e-27	117	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
345	B1JSS3	383	BIOF_YERPY 8-amino-7-oxononanoate synthase OS...	413	3e-27	116	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
346	A7FKM8	383	BIOF_YERP3 8-amino-7-oxononanoate synthase OS...	413	3e-27	116	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
347	Q55FL5	479	SPTC1_DICDI Serine palmitoyltransferase 1 OS=...	269	3e-26	115	28	50	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:dictyBase.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; ISS:dictyBase.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase.
348	A8GBC6	383	BIOF_SERP5 8-amino-7-oxononanoate synthase OS...	363	5e-26	113	29	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
349	Q477A3	408	BIOF_CUPPJ 8-amino-7-oxononanoate synthase OS...	384	2e-25	112	31	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
350	A1T8U6	380	BIKB_MYCVP Putative 8-amino-7-oxononanoate sy...	377	5e-25	110	31	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
351	P45487	385	BIKB_MYCLE Putative 8-amino-7-oxononanoate sy...	345	4e-23	104	30	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
352	B8ZR84	385	BIKB_MYCLB Putative 8-amino-7-oxononanoate sy...	345	4e-23	104	30	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
353	Q740R7	381	BIKB_MYCPA Putative 8-amino-7-oxononanoate sy...	391	1e-22	103	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
354	Q3MHG1	473	SPTC1_BOVIN Serine palmitoyltransferase 1 OS=...	264	1e-21	101	27	46	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0035339; C:SPOTS complex; ISS:UniProtKB.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
355	P0A4X4	386	BIKB_MYCTU Putative 8-amino-7-oxononanoate sy...	345	1e-21	100	29	48	GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IDA:MTBBASE.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IDA:MTBBASE.
356	A5WMQ5	386	BIKB_MYCTF Putative 8-amino-7-oxononanoate sy...	345	1e-21	100	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
357	A5U2S6	386	BIKB_MYCTA Putative 8-amino-7-oxononanoate sy...	345	1e-21	100	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
358	A1KJ00	386	BIKB_MYCBP Putative 8-amino-7-oxononanoate sy...	345	1e-21	100	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
359	P0A4X5	386	BIKB_MYCBO Putative 8-amino-7-oxononanoate sy...	345	1e-21	100	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
360	O15269	473	SPTC1_HUMAN Serine palmitoyltransferase 1 OS=...	264	1e-21	101	27	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0035339; C:SPOTS complex; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
361	Q60HD1	473	SPTC1_MACFA Serine palmitoyltransferase 1 OS=...	264	2e-21	101	27	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0035339; C:SPOTS complex; ISS:UniProtKB.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.

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