Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR232W
Length:
548
Number of sequences:
5887
Description:
YDR232W HEM1 SGDID:S000002640, Chr IV from 927452-929098, Genome Release 64-1-1, Verified ORF, "5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P43091    627   HEM1_OPSTA 5-aminolevulinate synthase, nonspe...4253e-121     377     43     65GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
32Q8VC19    642   HEM1_MOUSE 5-aminolevulinate synthase, nonspe...4185e-120     374     44     65GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
33Q9XS79    640   HEM1_DELLE 5-aminolevulinate synthase, nonspe...4162e-119     373     44     65GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
34Q5R9R9    640   HEM1_PONAB 5-aminolevulinate synthase, nonspe...4163e-119     372     44     65GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
35P13196    640   HEM1_HUMAN 5-aminolevulinate synthase, nonspe...4163e-119     372     44     65GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0006783; P:heme biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
36Q9ZCB8    414   HEM1_RICPR 5-aminolevulinate synthase OS=Rick...4172e-117     360     45     64
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
37P08080    404   HEM1_RHIME 5-aminolevulinate synthase OS=meli...4237e-117     358     47     63
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
38Q68VS3    414   HEM1_RICTY 5-aminolevulinate synthase OS=Rick...4178e-116     356     44     63
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
39P07997    635   HEM1_CHICK 5-aminolevulinate synthase, nonspe...4188e-114     358     43     64GO:0005829; C:cytosol; TAS:Reactome.::GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006783; P:heme biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
40P18080    513   HEM0_CHICK 5-aminolevulinate synthase, erythr...4284e-105     332     44     59GO:0005829; C:cytosol; TAS:Reactome.::GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0006783; P:heme biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
41O31777    392   BIKB_BACSU Putative 8-amino-7-oxononanoate sy...3764e-66     226     35     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
42A7Z4X1    391   BIKB_BACA2 Putative 8-amino-7-oxononanoate sy...4141e-64     221     33     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
43A8FDG9    392   BIKB_BACP2 Putative 8-amino-7-oxononanoate sy...3753e-60     210     34     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
44P37419    398   BIKB_SALTY Putative 8-amino-7-oxononanoate sy...3593e-60     210     33     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
45P0AB77    398   KBL_ECOLI 2-amino-3-ketobutyrate coenzyme A l...3592e-59     207     33     54GO:0005737; C:cytoplasm; IDA:EcoliWiki.
GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0016874; F:ligase activity; IDA:EcoliWiki.::GO:0046872; F:metal ion binding; IDA:EcoliWiki.::GO:0042803; F:protein homodimerization activity; IPI:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IDA:EcoliWiki.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
46P0AB79    398   BIKB_SHIFL Putative 8-amino-7-oxononanoate sy...3592e-59     207     33     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
47P0AB78    398   BIKB_ECO57 Putative 8-amino-7-oxononanoate sy...3592e-59     207     33     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
48A6TU88    395   BIKB_ALKMQ Putative 8-amino-7-oxononanoate sy...3963e-59     207     33     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
49O75600    419   KBL_HUMAN 2-amino-3-ketobutyrate coenzyme A l...4119e-59     207     31     50GO:0005739; C:mitochondrion; NAS:UniProtKB.
GO:0008890; F:glycine C-acetyltransferase activity; NAS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; NAS:UniProtKB.
50B0K590    395   BIKB_THEPX Putative 8-amino-7-oxononanoate sy...3803e-58     204     33     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
51B1YMC6    390   BIKB_EXIS2 Putative 8-amino-7-oxononanoate sy...3714e-58     204     35     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
52A3DBD5    388   BIOF_CLOTH Putative 8-amino-7-oxononanoate sy...4116e-58     204     34     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
53B0KC20    395   BIKB_THEP3 Putative 8-amino-7-oxononanoate sy...3721e-57     203     34     51
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
54B5EEV8    389   BIOF_GEOBB 8-amino-7-oxononanoate synthase OS...3911e-57     202     34     50
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
55B9M8U3    393   BIOF_GEOSF 8-amino-7-oxononanoate synthase OS...3802e-57     202     34     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
56A7Z5B4    386   BIOF_BACA2 Putative 8-amino-7-oxononanoate sy...4193e-57     202     32     49
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
57O88986    416   KBL_MOUSE 2-amino-3-ketobutyrate coenzyme A l...4094e-57     202     31     51GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
58Q0P5L8    419   KBL_BOVIN 2-amino-3-ketobutyrate coenzyme A l...4306e-57     202     30     49GO:0005743; C:mitochondrial inner membrane; ISS:AgBase.
GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
59A6LMP4    391   BIKB_THEM4 Putative 8-amino-7-oxononanoate sy...3811e-56     200     32     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
60B7ID58    391   BIKB_THEAB Putative 8-amino-7-oxononanoate sy...3781e-56     200     33     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
61Q21FY4    397   BIOF_SACD2 8-amino-7-oxononanoate synthase OS...4155e-56     199     31     50
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
records
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