UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR232W

Length:

548

Number of sequences:

5887

Description:

YDR232W HEM1 SGDID:S000002640, Chr IV from 927452-929098, Genome Release 64-1-1, Verified ORF, "5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
181	A5FZN8	381	BIOF_ACICJ Putative 8-amino-7-oxononanoate sy...	380	5e-39	150	32	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
182	Q119K2	393	BIOF_TRIEI Putative 8-amino-7-oxononanoate sy...	418	6e-39	151	31	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
183	B7KD70	380	BIOF_CYAP7 Putative 8-amino-7-oxononanoate sy...	363	2e-38	149	31	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
184	A9HVE9	396	BIOF_BORPD 8-amino-7-oxononanoate synthase OS...	422	2e-38	149	30	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
185	B0UKC8	379	BIKB_METS4 Putative 8-amino-7-oxononanoate sy...	381	3e-38	149	35	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
186	A6T6L6	385	BIOF_KLEP7 8-amino-7-oxononanoate synthase OS...	406	3e-38	149	28	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
187	B8HTV6	399	BIOF_CYAP4 Putative 8-amino-7-oxononanoate sy...	406	9e-38	147	30	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
188	O15270	562	SPTC2_HUMAN Serine palmitoyltransferase 2 OS=...	393	9e-38	150	28	48	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; IDA:UniProtKB.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
189	Q9CJU0	387	BIOF_PASMU Putative 8-amino-7-oxononanoate sy...	375	1e-37	147	30	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
190	Q146K3	394	BIOF_BURXL 8-amino-7-oxononanoate synthase OS...	372	1e-37	147	31	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
191	Q09925	603	LCB2_SCHPO Serine palmitoyltransferase 2 OS=S...	395	2e-37	149	28	46	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:PomBase.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; ISS:PomBase.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0030148; P:sphingolipid biosynthetic process; ISS:PomBase.
192	B8F713	380	BIOF_HAEPS Putative 8-amino-7-oxononanoate sy...	355	2e-37	146	30	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
193	B1Z7Y8	387	BIKB_METPB Putative 8-amino-7-oxononanoate sy...	371	2e-37	146	31	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
194	Q3M9A4	386	BIOF_ANAVT Putative 8-amino-7-oxononanoate sy...	370	2e-37	146	32	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
195	B2AG98	404	BIOF_CUPTR 8-amino-7-oxononanoate synthase OS...	374	3e-37	146	32	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
196	Q12F38	405	BIOF1_POLSJ 8-amino-7-oxononanoate synthase 1...	387	4e-37	146	32	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
197	Q5DZH9	383	BIOF_VIBF1 8-amino-7-oxononanoate synthase OS...	372	4e-37	145	31	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
198	B2JKH6	394	BIOF_BURP8 8-amino-7-oxononanoate synthase OS...	388	5e-37	145	31	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
199	P97363	560	SPTC2_MOUSE Serine palmitoyltransferase 2 OS=...	393	6e-37	147	27	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:MGI.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:MGI.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0046511; P:sphinganine biosynthetic process; IDA:MGI.::GO:0006686; P:sphingomyelin biosynthetic process; IMP:MGI.::GO:0046512; P:sphingosine biosynthetic process; IMP:MGI.
200	B2J1W1	394	BIOF_NOSP7 Putative 8-amino-7-oxononanoate sy...	377	6e-37	145	32	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
201	Q12D74	405	BIOF2_POLSJ 8-amino-7-oxononanoate synthase 2...	431	1e-36	144	30	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
202	B2SWS7	394	BIOF_BURPP 8-amino-7-oxononanoate synthase OS...	372	1e-36	144	30	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
203	Q7N6Q6	383	BIOF_PHOLL 8-amino-7-oxononanoate synthase OS...	411	1e-36	144	27	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
204	A1K6Q1	390	BIOF_AZOSB 8-amino-7-oxononanoate synthase OS...	403	1e-36	144	28	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
205	B6ESC6	383	BIOF_ALISL 8-amino-7-oxononanoate synthase OS...	371	2e-36	144	29	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
206	Q0BUV6	382	BIKB_GRABC Putative 8-amino-7-oxononanoate sy...	390	2e-36	143	32	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
207	O54694	560	SPTC2_CRIGR Serine palmitoyltransferase 2 OS=...	393	2e-36	145	27	47	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
208	Q0KF88	404	BIOF_CUPNH 8-amino-7-oxononanoate synthase OS...	382	3e-36	143	32	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
209	Q6A6M4	653	BIOWF_PROAC Biotin biosynthesis bifunctional ...	373	4e-36	145	29	47
									GO:0042410; F:6-carboxyhexanoate-CoA ligase activity; IEA:EC.::GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
210	Q8DJ97	391	BIOF_THEEB Putative 8-amino-7-oxononanoate sy...	359	6e-36	142	33	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
211	Q6LPR3	392	BIOF_PHOPR 8-amino-7-oxononanoate synthase OS...	373	6e-36	142	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.

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