| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P09950 | 548 | HEM1_YEAST 5-aminolevulinate synthase, mitoch... | 548 | 0 | 1138 | 100 | 100 | GO:0005759; C:mitochondrial matrix; IDA:SGD. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IMP:SGD. | 2 | Q6FXE3 | 530 | HEM1_CANGA 5-aminolevulinate synthase, mitoch... | 484 | 0 | 856 | 83 | 90 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 3 | P78698 | 570 | HEM1_KLULA 5-aminolevulinate synthase, mitoch... | 493 | 0 | 815 | 77 | 89 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 4 | Q75DX7 | 556 | HEM1_ASHGO 5-aminolevulinate synthase, mitoch... | 482 | 0 | 760 | 74 | 85 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 5 | Q6BX71 | 575 | HEM1_DEBHA 5-aminolevulinate synthase, mitoch... | 487 | 0 | 697 | 67 | 81 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 6 | O94069 | 564 | HEM1_CANAL 5-aminolevulinate synthase, mitoch... | 513 | 0 | 672 | 65 | 77 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IMP:CGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IMP:CGD. | 7 | P38092 | 648 | HEM1_EMENI 5-aminolevulinate synthase, mitoch... | 484 | 0 | 612 | 61 | 75 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 8 | Q6CCW0 | 563 | HEM1_YARLI 5-aminolevulinate synthase, mitoch... | 457 | 0 | 597 | 63 | 75 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 9 | Q7RVY5 | 629 | HEM1_NEUCR 5-aminolevulinate synthase, mitoch... | 480 | 0 | 579 | 58 | 73 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 10 | Q92403 | 621 | HEM1_AGABI 5-aminolevulinate synthase, mitoch... | 474 | 0 | 558 | 58 | 73 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 11 | O14092 | 558 | HEM1_SCHPO 5-aminolevulinate synthase, mitoch... | 430 | 3e-164 | 485 | 56 | 70 | GO:0005759; C:mitochondrial matrix; ISS:PomBase. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; ISS:PomBase. | 12 | P26505 | 405 | HEM1_RHIRD 5-aminolevulinate synthase OS=radi... | 424 | 3e-133 | 400 | 49 | 64 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 13 | P08262 | 409 | HEM1_BRAJA 5-aminolevulinate synthase OS=Brad... | 422 | 7e-133 | 400 | 47 | 66 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 14 | P43090 | 582 | HEM0_OPSTA 5-aminolevulinate synthase, erythr... | 422 | 7e-132 | 403 | 46 | 67 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 15 | Q04512 | 407 | HEM1_RHOS4 5-aminolevulinate synthase 1 OS=15... | 424 | 1e-131 | 397 | 49 | 64 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 16 | Q9YHT4 | 583 | HEM0_DANRE 5-aminolevulinate synthase, erythr... | 426 | 1e-129 | 397 | 46 | 65 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0035162; P:embryonic hemopoiesis; IMP:ZFIN.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 17 | P08680 | 587 | HEM0_MOUSE 5-aminolevulinate synthase, erythr... | 434 | 2e-128 | 394 | 44 | 65 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0006783; P:heme biosynthetic process; IMP:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; IMP:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 18 | P18079 | 409 | HEM1_RHOCB 5-aminolevulinate synthase OS=Rhod... | 426 | 4e-128 | 387 | 48 | 63 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 19 | Q5R557 | 587 | HEM0_PONAB 5-aminolevulinate synthase, erythr... | 426 | 5e-128 | 393 | 44 | 66 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 20 | P22557 | 587 | HEM0_HUMAN 5-aminolevulinate synthase, erythr... | 426 | 3e-127 | 391 | 44 | 66 | GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IDA:UniProtKB.::GO:0050662; F:coenzyme binding; ISS:UniProtKB.::GO:0016594; F:glycine binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0032364; P:oxygen homeostasis; NAS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 21 | Q63147 | 587 | HEM0_RAT 5-aminolevulinate synthase, erythroi... | 434 | 3e-127 | 391 | 44 | 64 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0050662; F:coenzyme binding; IDA:RGD.::GO:0016594; F:glycine binding; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0007595; P:lactation; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0010288; P:response to lead ion; IEP:RGD. | 22 | Q9XT75 | 582 | HEM0_DELLE 5-aminolevulinate synthase, erythr... | 426 | 5e-127 | 390 | 44 | 66 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 23 | Q3ZC31 | 587 | HEM0_BOVIN 5-aminolevulinate synthase, erythr... | 426 | 1e-125 | 387 | 43 | 65 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 24 | Q06965 | 407 | HEM0_RHOS4 5-aminolevulinate synthase 2 OS=15... | 418 | 9e-125 | 379 | 47 | 64 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 25 | P13195 | 642 | HEM1_RAT 5-aminolevulinate synthase, nonspeci... | 418 | 4e-124 | 385 | 45 | 66 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0032025; P:response to cobalt ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0010045; P:response to nickel cation; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0070541; P:response to platinum ion; IEP:RGD. | 26 | Q4UJV4 | 414 | HEM1_RICFE 5-aminolevulinate synthase OS=Rick... | 417 | 8e-124 | 377 | 46 | 63 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 27 | P43089 | 409 | HEM1_PARDP 5-aminolevulinate synthase OS=Para... | 426 | 1e-123 | 376 | 49 | 63 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 28 | Q1RIV2 | 414 | HEM1_RICBR 5-aminolevulinate synthase OS=Rick... | 417 | 9e-123 | 374 | 45 | 63 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 29 | A6QLI6 | 647 | HEM1_BOVIN 5-aminolevulinate synthase, nonspe... | 414 | 3e-122 | 380 | 45 | 66 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 30 | Q92G23 | 414 | HEM1_RICCN 5-aminolevulinate synthase OS=Rick... | 420 | 7e-122 | 372 | 45 | 63 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 31 | P43091 | 627 | HEM1_OPSTA 5-aminolevulinate synthase, nonspe... | 425 | 3e-121 | 377 | 43 | 65 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. |
