UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR227W

Length:

1358

Number of sequences:

5887

Description:

YDR227W SIR4 SGDID:S000002635, Chr IV from 917571-921647, Genome Release 64-1-1, Verified ORF, "Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; potentially phosphorylated by Cdc28p; some alleles of SIR4 prolong lifespan"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P11978	1358	SIR4_YEAST Regulatory protein SIR4 OS=Sacchar...	1358	0	2752	100	100	GO:0005677; C:chromatin silencing complex; IDA:SGD.::GO:0000783; C:nuclear telomere cap complex; IDA:SGD.::GO:0005724; C:nuclear telomeric heterochromatin; IDA:SGD.
									GO:0003690; F:double-stranded DNA binding; IDA:SGD.::GO:0042393; F:histone binding; TAS:SGD.::GO:0031491; F:nucleosome binding; IDA:SGD.::GO:0030527; F:structural constituent of chromatin; TAS:SGD.
									GO:0006342; P:chromatin silencing; TAS:SGD.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IDA:SGD.::GO:0001308; P:negative regulation of chromatin silencing involved in replicative cell aging; IDA:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2	Q38681	492	VATB1_ACEAT V-type proton ATPase subunit B 1 ...	114	0.022	42.7	28	50	GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
									GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
3	Q1CUH2	260	NADE_HELPH NH(3)-dependent NAD(+) synthetase ...	94	0.69	37.4	32	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
									GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
4	Q38680	492	VATB2_ACEAT V-type proton ATPase subunit B 2 ...	77	0.81	37.7	32	52	GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
									GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
5	Q25691	494	VATB_PLAFA V-type proton ATPase subunit B OS=...	158	1.9	36.2	27	47	GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
									GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
6	Q40078	488	VATB1_HORVU V-type proton ATPase subunit B 1 ...	119	3.5	35.4	27	48	GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
									GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
7	Q9SZN1	487	VATB2_ARATH V-type proton ATPase subunit B2 O...	119	3.7	35.4	27	48	GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
									GO:0051015; F:actin filament binding; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:InterPro.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
									GO:0051017; P:actin filament bundle assembly; IDA:TAIR.::GO:0051693; P:actin filament capping; IDA:TAIR.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
8	Q40079	483	VATB2_HORVU V-type proton ATPase subunit B 2 ...	119	3.9	35.4	27	48	GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
									GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
9	Q43432	488	VATB1_GOSHI V-type proton ATPase subunit B 1 ...	119	4.2	35.4	27	48	GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
									GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
10	O25096	260	NADE_HELPY NH(3)-dependent NAD(+) synthetase ...	94	7.9	33.9	30	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
									GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
11	B5ZA97	260	NADE_HELPG NH(3)-dependent NAD(+) synthetase ...	94	8.4	33.9	30	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
									GO:0009435; P:NAD biosynthetic process; IEA:InterPro.

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