Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR211W
Length:
712
Number of sequences:
5887
Description:
YDR211W GCD6 SGDID:S000002619, Chr IV from 884727-886865, Genome Release 64-1-1, Verified ORF, "Catalytic epsilon subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32501    712   EI2BE_YEAST Translation initiation factor eIF...7120     1471     100     100GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:SGD.::GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:SGD.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IGI:SGD.
GO:0006446; P:regulation of translational initiation; IDA:SGD.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
2P87163    732   EI2BE_CANAL Translation initiation factor eIF...7230     756     54     73GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:CGD.
GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:CGD.
GO:0016070; P:RNA metabolic process; IEA:InterPro.
3P56287    678   EI2BE_SCHPO Probable translation initiation f...6880     541     44     62GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase.
GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
4Q54RF3    707   EI2BE_DICDI Translation initiation factor eIF...4341e-97     323     41     62GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase.::GO:0043614; C:multi-eIF complex; ISS:dictyBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:dictyBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
5Q64350    716   EI2BE_RAT Translation initiation factor eIF-2...7174e-90     303     30     49GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; TAS:RGD.::GO:0031369; F:translation initiation factor binding; IDA:RGD.
GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
6Q8CHW4    717   EI2BE_MOUSE Translation initiation factor eIF...7075e-87     295     30     49GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
7P47823    721   EI2BE_RABIT Translation initiation factor eIF...7009e-85     288     29     49GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
8Q13144    721   EI2BE_HUMAN Translation initiation factor eIF...6943e-82     281     28     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.::GO:0031369; F:translation initiation factor binding; ISS:UniProtKB.
GO:0014002; P:astrocyte development; IMP:UniProtKB.::GO:0042552; P:myelination; IMP:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; IMP:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro.
9P37820    359   MPG1_SULAC Putative mannose-1-phosphate guany...4213e-23     105     26     45
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
10A3QMC8    365   GMPPB_CAEEL Mannose-1-phosphate guanyltransfe...4090.000000000000003     81.6     25     41
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
11Q61S97    364   GMPPB_CAEBR Mannose-1-phosphate guanyltransfe...4100.00000000000003     78.6     23     40
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
12P56288    458   EI2BG_SCHPO Probable translation initiation f...4360.0000000000003     75.9     22     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase.::GO:0005840; C:ribosome; ISS:PomBase.
GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.
13P70541    452   EI2BG_RAT Translation initiation factor eIF-2...4460.000000000005     72.4     21     40GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:RGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.
14Q922H4    420   GMPPA_MOUSE Mannose-1-phosphate guanyltransfe...3850.00000000001     71.2     22     44
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
15P80361    404   EI2BG_CAEEL Probable translation initiation f...4120.00000000001     70.9     23     43GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.
16O60064    414   YBB2_SCHPO Probable mannose-1-phosphate guany...3750.00000000002     70.1     24     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; ISS:PomBase.
GO:0009298; P:GDP-mannose biosynthetic process; IC:PomBase.
17Q5XIC1    420   GMPPA_RAT Mannose-1-phosphate guanyltransfera...3840.00000000002     70.1     23     43GO:0005829; C:cytosol; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
18Q68EQ1    360   GMPPB_XENTR Mannose-1-phosphate guanyltransfe...4070.00000000003     69.3     22     42
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
19Q68EY9    360   GMPBA_XENLA Mannose-1-phosphate guanyltransfe...4070.00000000003     69.3     22     41
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
20Q8BTZ7    360   GMPPB_MOUSE Mannose-1-phosphate guanyltransfe...3910.00000000003     69.3     23     39GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
21Q96IJ6    420   GMPPA_HUMAN Mannose-1-phosphate guanyltransfe...3850.00000000005     68.9     22     44
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.::GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
22O22287    361   GMPP1_ARATH Mannose-1-phosphate guanylyltrans...4090.00000000009     67.8     23     41GO:0005829; C:cytosol; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IMP:TAIR.
GO:0030244; P:cellulose biosynthetic process; IMP:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0019853; P:L-ascorbic acid biosynthetic process; IMP:TAIR.::GO:0060359; P:response to ammonium ion; IMP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IEP:TAIR.::GO:0010193; P:response to ozone; IEP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.
23B0CM52    420   GMPPA_PAPAN Mannose-1-phosphate guanyltransfe...3850.00000000009     68.2     22     44
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
24Q7SXP8    422   GMPAB_DANRE Mannose-1-phosphate guanyltransfe...3860.0000000001     68.2     21     44
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
25A2VD83    360   GMPBB_XENLA Mannose-1-phosphate guanyltransfe...4160.0000000001     67.4     21     40
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
26Q6GMK8    422   GMPAA_DANRE Mannose-1-phosphate guanyltransfe...4550.0000000002     67     22     43
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
27Q8DT53    379   GLGC_STRMU Glucose-1-phosphate adenylyltransf...4230.0000000004     66.2     22     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008878; F:glucose-1-phosphate adenylyltransferase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.
28Q4R6T3    452   EI2BG_MACFA Translation initiation factor eIF...4580.0000000004     66.2     21     40GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
29Q66KG5    426   GMPAB_XENLA Mannose-1-phosphate guanyltransfe...3790.0000000005     65.9     22     45
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.
30Q6Z9A3    361   GMPP3_ORYSJ Probable mannose-1-phosphate guan...4080.0000000007     65.1     23     43
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
31Q6CCU3    363   MPG1_YARLI Mannose-1-phosphate guanyltransfer...4240.000000001     64.7     23     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
records
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