rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P32501 | 712 | EI2BE_YEAST Translation initiation factor eIF... | 712 | 0 | 1471 | 100 | 100 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:SGD.::GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:SGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IGI:SGD. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IDA:SGD.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 2 | P87163 | 732 | EI2BE_CANAL Translation initiation factor eIF... | 723 | 0 | 756 | 54 | 73 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:CGD. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:CGD. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 3 | P56287 | 678 | EI2BE_SCHPO Probable translation initiation f... | 688 | 0 | 541 | 44 | 62 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase. | | | | | | | | | | GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 4 | Q54RF3 | 707 | EI2BE_DICDI Translation initiation factor eIF... | 434 | 1e-97 | 323 | 41 | 62 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase.::GO:0043614; C:multi-eIF complex; ISS:dictyBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:dictyBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 5 | Q64350 | 716 | EI2BE_RAT Translation initiation factor eIF-2... | 717 | 4e-90 | 303 | 30 | 49 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; TAS:RGD.::GO:0031369; F:translation initiation factor binding; IDA:RGD. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 6 | Q8CHW4 | 717 | EI2BE_MOUSE Translation initiation factor eIF... | 707 | 5e-87 | 295 | 30 | 49 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 7 | P47823 | 721 | EI2BE_RABIT Translation initiation factor eIF... | 700 | 9e-85 | 288 | 29 | 49 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 8 | Q13144 | 721 | EI2BE_HUMAN Translation initiation factor eIF... | 694 | 3e-82 | 281 | 28 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.::GO:0031369; F:translation initiation factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0014002; P:astrocyte development; IMP:UniProtKB.::GO:0042552; P:myelination; IMP:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; IMP:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 9 | P37820 | 359 | MPG1_SULAC Putative mannose-1-phosphate guany... | 421 | 3e-23 | 105 | 26 | 45 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 10 | A3QMC8 | 365 | GMPPB_CAEEL Mannose-1-phosphate guanyltransfe... | 409 | 0.000000000000003 | 81.6 | 25 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 11 | Q61S97 | 364 | GMPPB_CAEBR Mannose-1-phosphate guanyltransfe... | 410 | 0.00000000000003 | 78.6 | 23 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 12 | P56288 | 458 | EI2BG_SCHPO Probable translation initiation f... | 436 | 0.0000000000003 | 75.9 | 22 | 43 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase.::GO:0005840; C:ribosome; ISS:PomBase. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase. | | | | | | | | | | GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase. | 13 | P70541 | 452 | EI2BG_RAT Translation initiation factor eIF-2... | 446 | 0.000000000005 | 72.4 | 21 | 40 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:RGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB. | 14 | Q922H4 | 420 | GMPPA_MOUSE Mannose-1-phosphate guanyltransfe... | 385 | 0.00000000001 | 71.2 | 22 | 44 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 15 | P80361 | 404 | EI2BG_CAEEL Probable translation initiation f... | 412 | 0.00000000001 | 70.9 | 23 | 43 | GO:0005737; C:cytoplasm; IDA:WormBase. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase. | 16 | O60064 | 414 | YBB2_SCHPO Probable mannose-1-phosphate guany... | 375 | 0.00000000002 | 70.1 | 24 | 43 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; ISS:PomBase. | | | | | | | | | | GO:0009298; P:GDP-mannose biosynthetic process; IC:PomBase. | 17 | Q5XIC1 | 420 | GMPPA_RAT Mannose-1-phosphate guanyltransfera... | 384 | 0.00000000002 | 70.1 | 23 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 18 | Q68EQ1 | 360 | GMPPB_XENTR Mannose-1-phosphate guanyltransfe... | 407 | 0.00000000003 | 69.3 | 22 | 42 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 19 | Q68EY9 | 360 | GMPBA_XENLA Mannose-1-phosphate guanyltransfe... | 407 | 0.00000000003 | 69.3 | 22 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 20 | Q8BTZ7 | 360 | GMPPB_MOUSE Mannose-1-phosphate guanyltransfe... | 391 | 0.00000000003 | 69.3 | 23 | 39 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 21 | Q96IJ6 | 420 | GMPPA_HUMAN Mannose-1-phosphate guanyltransfe... | 385 | 0.00000000005 | 68.9 | 22 | 44 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.::GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. | 22 | O22287 | 361 | GMPP1_ARATH Mannose-1-phosphate guanylyltrans... | 409 | 0.00000000009 | 67.8 | 23 | 41 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IMP:TAIR. | | | | | | | | | | GO:0030244; P:cellulose biosynthetic process; IMP:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0019853; P:L-ascorbic acid biosynthetic process; IMP:TAIR.::GO:0060359; P:response to ammonium ion; IMP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IEP:TAIR.::GO:0010193; P:response to ozone; IEP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR. | 23 | B0CM52 | 420 | GMPPA_PAPAN Mannose-1-phosphate guanyltransfe... | 385 | 0.00000000009 | 68.2 | 22 | 44 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 24 | Q7SXP8 | 422 | GMPAB_DANRE Mannose-1-phosphate guanyltransfe... | 386 | 0.0000000001 | 68.2 | 21 | 44 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 25 | A2VD83 | 360 | GMPBB_XENLA Mannose-1-phosphate guanyltransfe... | 416 | 0.0000000001 | 67.4 | 21 | 40 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 26 | Q6GMK8 | 422 | GMPAA_DANRE Mannose-1-phosphate guanyltransfe... | 455 | 0.0000000002 | 67 | 22 | 43 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 27 | Q8DT53 | 379 | GLGC_STRMU Glucose-1-phosphate adenylyltransf... | 423 | 0.0000000004 | 66.2 | 22 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008878; F:glucose-1-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW. | 28 | Q4R6T3 | 452 | EI2BG_MACFA Translation initiation factor eIF... | 458 | 0.0000000004 | 66.2 | 21 | 40 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB. | 29 | Q66KG5 | 426 | GMPAB_XENLA Mannose-1-phosphate guanyltransfe... | 379 | 0.0000000005 | 65.9 | 22 | 45 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 30 | Q6Z9A3 | 361 | GMPP3_ORYSJ Probable mannose-1-phosphate guan... | 408 | 0.0000000007 | 65.1 | 23 | 43 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | | 31 | Q6CCU3 | 363 | MPG1_YARLI Mannose-1-phosphate guanyltransfer... | 424 | 0.000000001 | 64.7 | 23 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. |