Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR205W
Length:
724
Number of sequences:
5887
Description:
YDR205W MSC2 SGDID:S000002613, Chr IV from 859346-861520, Genome Release 64-1-1, Verified ORF, "Member of the cation diffusion facilitator family, localizes to the endoplasmic reticulum and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q83SA2    313   ZITB_SHIFL Zinc transporter zitB OS=Shigella ...2041e-17     88.6     36     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
32P75757    313   ZITB_ECOLI Zinc transporter zitB OS=Escherich...2041e-17     87.8     36     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
33P20107    442   ZRC1_YEAST Zinc/cadmium resistance protein OS...870.000009     52.4     43     57GO:0000324; C:fungal-type vacuole; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005385; F:zinc ion transmembrane transporter activity; IMP:SGD.
GO:0006882; P:cellular zinc ion homeostasis; IMP:SGD.::GO:0006824; P:cobalt ion transport; NAS:SGD.::GO:0006749; P:glutathione metabolic process; NAS:SGD.::GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.
34O13918    387   ZHF1_SCHPO Zinc homeostasis factor 1 OS=Schiz...780.00000001     61.2     44     64GO:0005789; C:endoplasmic reticulum membrane; IDA:PomBase.::GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005385; F:zinc ion transmembrane transporter activity; IMP:PomBase.
GO:0006876; P:cellular cadmium ion homeostasis; IMP:PomBase.::GO:0006877; P:cellular cobalt ion homeostasis; IMP:PomBase.::GO:0006882; P:cellular zinc ion homeostasis; IMP:PomBase.
35Q6ICY4    393   MTPC2_ARATH Metal tolerance protein C2 OS=Ara...2490.00000000000002     79.7     25     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0009624; P:response to nematode; IEP:TAIR.
36Q54QU8    543   Y3629_DICDI Probable zinc transporter protein...2750.0000000000003     76.6     23     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005385; F:zinc ion transmembrane transporter activity; ISS:dictyBase.
37O35149    430   ZNT4_MOUSE Zinc transporter 4 OS=Mus musculus...2590.0000000000003     75.9     24     49GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0055069; P:zinc ion homeostasis; IMP:MGI.
38O55174    430   ZNT4_RAT Zinc transporter 4 OS=Rattus norvegi...2590.0000000000006     75.1     24     49GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:RGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005385; F:zinc ion transmembrane transporter activity; IDA:RGD.
GO:0007595; P:lactation; IEP:RGD.::GO:0033189; P:response to vitamin A; IEP:RGD.::GO:0010043; P:response to zinc ion; IEP:RGD.
39Q6XR72    485   ZNT10_HUMAN Zinc transporter 10 OS=Homo sapie...1090.0000003     57.4     34     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
40O14863    429   ZNT4_HUMAN Zinc transporter 4 OS=Homo sapiens...2280.000000000003     73.2     26     50GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005770; C:late endosome; IDA:BHF-UCL.
GO:0005385; F:zinc ion transmembrane transporter activity; TAS:ProtInc.
GO:0061088; P:regulation of sequestering of zinc ion; IDA:BHF-UCL.::GO:0009636; P:response to toxin; IDA:UniProtKB.
41Q2HJ10    371   ZNT2_MOUSE Zinc transporter 2 OS=Mus musculus...2080.000000000003     72.4     25     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
42P32798    439   COT1_YEAST Cobalt uptake protein COT1 OS=Sacc...670.00001     52.4     45     64GO:0000324; C:fungal-type vacuole; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0015087; F:cobalt ion transmembrane transporter activity; IMP:SGD.::GO:0005385; F:zinc ion transmembrane transporter activity; IGI:SGD.
GO:0006882; P:cellular zinc ion homeostasis; IMP:SGD.
43Q3UVU3    470   ZNT10_MOUSE Zinc transporter 10 OS=Mus muscul...1410.0000002     57.8     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
44Q5I020    375   ZNT8_XENLA Zinc transporter 8 OS=Xenopus laev...2590.00000000002     69.7     25     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
45Q95QW4    561   CDF1_CAEEL Cation diffusion facilitator famil...1190.005     43.9     29     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:WormBase.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0071294; P:cellular response to zinc ion; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0046579; P:positive regulation of Ras protein signal transduction; IGI:WormBase.::GO:0040026; P:positive regulation of vulval development; IGI:WormBase.::GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
46Q6DBM8    375   MTPB_ARATH Metal tolerance protein B OS=Arabi...2490.0000000005     65.5     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
47Q8IWU4    369   ZNT8_HUMAN Zinc transporter 8 OS=Homo sapiens...1890.0000000008     65.1     28     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030667; C:secretory granule membrane; TAS:Reactome.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IC:BHF-UCL.::GO:0005385; F:zinc ion transmembrane transporter activity; IDA:BHF-UCL.
GO:0030073; P:insulin secretion; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.::GO:0061088; P:regulation of sequestering of zinc ion; ISS:BHF-UCL.::GO:0060627; P:regulation of vesicle-mediated transport; ISS:BHF-UCL.::GO:0009749; P:response to glucose stimulus; IMP:BHF-UCL.::GO:0032119; P:sequestering of zinc ion; IDA:BHF-UCL.
48Q5XHB4    374   ZNT8_XENTR Zinc transporter 8 OS=Xenopus trop...2490.0000000009     64.7     23     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
49Q08E25    388   ZNT3_BOVIN Zinc transporter 3 OS=Bos taurus (...2440.000000001     64.7     26     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
50P97441    388   ZNT3_MOUSE Zinc transporter 3 OS=Mus musculus...2430.000000002     63.9     26     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IDA:MGI.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0010312; P:detoxification of zinc ion; TAS:BHF-UCL.::GO:0051050; P:positive regulation of transport; IGI:MGI.::GO:0061088; P:regulation of sequestering of zinc ion; TAS:BHF-UCL.::GO:0032119; P:sequestering of zinc ion; TAS:BHF-UCL.::GO:0006829; P:zinc ion transport; TAS:BHF-UCL.
51Q62941    359   ZNT2_RAT Zinc transporter 2 OS=Rattus norvegi...2090.000000005     62.4     22     47GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:RGD.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005385; F:zinc ion transmembrane transporter activity; IDA:RGD.
52Q62720    507   ZNT1_RAT Zinc transporter 1 OS=Rattus norvegi...250.37     37.7     60     84GO:0016021; C:integral to membrane; IDA:RGD.::GO:0030315; C:T-tubule; IDA:BHF-UCL.
GO:0019855; F:calcium channel inhibitor activity; IMP:BHF-UCL.::GO:0005385; F:zinc ion transmembrane transporter activity; IDA:MGI.
GO:0070574; P:cadmium ion transmembrane transport; IMP:BHF-UCL.::GO:0070509; P:calcium ion import; IMP:BHF-UCL.::GO:0071585; P:detoxification of cadmium ion; IMP:BHF-UCL.::GO:0046929; P:negative regulation of neurotransmitter secretion; IMP:BHF-UCL.
53Q8BGG0    367   ZNT8_MOUSE Zinc transporter 8 OS=Mus musculus...1890.00000002     60.8     28     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
GO:0030073; P:insulin secretion; IMP:BHF-UCL.::GO:0009749; P:response to glucose stimulus; IMP:BHF-UCL.
54P0CE46    368   ZNT8_RAT Zinc transporter 8 OS=Rattus norvegi...1890.00000002     60.8     29     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0030073; P:insulin secretion; IMP:RGD.::GO:0032024; P:positive regulation of insulin secretion; IMP:BHF-UCL.::GO:0061088; P:regulation of sequestering of zinc ion; IMP:BHF-UCL.::GO:0060627; P:regulation of vesicle-mediated transport; IMP:BHF-UCL.::GO:0009749; P:response to glucose stimulus; IMP:BHF-UCL.::GO:0034341; P:response to interferon-gamma; IEP:RGD.::GO:0070555; P:response to interleukin-1; IEP:RGD.
55Q60738    503   ZNT1_MOUSE Zinc transporter 1 OS=Mus musculus...250.41     37.7     60     84GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0019855; F:calcium channel inhibitor activity; IDA:BHF-UCL.
GO:0006874; P:cellular calcium ion homeostasis; IDA:BHF-UCL.::GO:0006882; P:cellular zinc ion homeostasis; IDA:BHF-UCL.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0090281; P:negative regulation of calcium ion import; IDA:BHF-UCL.::GO:0071584; P:negative regulation of zinc ion import; IDA:BHF-UCL.
56Q6QIX3    388   ZNT3_RAT Zinc transporter 3 OS=Rattus norvegi...2180.00000003     60.1     25     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
57Q9Y6M5    507   ZNT1_HUMAN Zinc transporter 1 OS=Homo sapiens...1330.17     38.9     29     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030315; C:T-tubule; ISS:BHF-UCL.
GO:0019855; F:calcium channel inhibitor activity; ISS:BHF-UCL.
GO:0070574; P:cadmium ion transmembrane transport; ISS:BHF-UCL.::GO:0006874; P:cellular calcium ion homeostasis; ISS:BHF-UCL.::GO:0006882; P:cellular zinc ion homeostasis; ISS:BHF-UCL.::GO:0090281; P:negative regulation of calcium ion import; ISS:BHF-UCL.::GO:0046929; P:negative regulation of neurotransmitter secretion; ISS:BHF-UCL.::GO:0071584; P:negative regulation of zinc ion import; ISS:BHF-UCL.
58P74068    310   Y1263_SYNY3 Uncharacterized transporter sll12...1780.00000007     58.5     26     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
59Q4R6K2    505   ZNT1_MACFA Zinc transporter 1 OS=Macaca fasci...1330.19     38.5     29     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
60Q99726    388   ZNT3_HUMAN Zinc transporter 3 OS=Homo sapiens...2400.00000009     58.5     25     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005770; C:late endosome; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015633; F:zinc transporting ATPase activity; TAS:ProtInc.
GO:0061088; P:regulation of sequestering of zinc ion; IDA:BHF-UCL.
61Q5R617    388   ZNT3_PONAB Zinc transporter 3 OS=Pongo abelii...2400.00000009     58.5     25     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
records
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