Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR191W
Length:
370
Number of sequences:
5887
Description:
YDR191W HST4 SGDID:S000002599, Chr IV from 842337-843449, Genome Release 64-1-1, Verified ORF, "Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q9FE17    473   SIR1_ARATH NAD-dependent protein deacetylase ...3270.000000008     60.5     27     40
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
92Q5JG47    257   NPD_PYRKO NAD-dependent protein deacylase OS=...2330.000000009     59.3     24     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
93B8ARK7    484   SIR1_ORYSI NAD-dependent protein deacetylase ...1770.00000001     60.5     30     46
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
94Q94AQ6    373   SIR4_ARATH NAD-dependent protein deacetylase ...2710.00000001     59.7     22     38GO:0005634; C:nucleus; IDA:TAIR.
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0031348; P:negative regulation of defense response; IMP:TAIR.::GO:0006476; P:protein deacetylation; IEA:InterPro.
95P0CS88    354   HST22_EMENI NAD-dependent protein deacetylase...2910.00000001     59.7     24     41
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
96Q5V4Q5    260   NPD_HALMA NAD-dependent protein deacetylase O...2340.00000001     58.5     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
97Q9WYW0    246   NPD_THEMA NAD-dependent protein deacetylase O...2270.00000002     58.2     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
98Q9Y6E7    314   SIR4_HUMAN NAD-dependent protein deacetylase ...2560.00000003     58.5     25     42GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0046676; P:negative regulation of insulin secretion; IMP:UniProtKB.::GO:0006471; P:protein ADP-ribosylation; TAS:BHF-UCL.::GO:0006476; P:protein deacetylation; IEA:InterPro.
99Q885X7    248   NPD2_PSESM NAD-dependent protein deacylase 2 ...2340.00000003     57.8     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
100Q1JQC6    315   SIR4_BOVIN NAD-dependent protein deacetylase ...2510.00000003     58.2     25     42GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.
101Q9NRC8    400   SIR7_HUMAN NAD-dependent protein deacetylase ...2880.00000003     58.5     22     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005731; C:nucleolus organizer region; IDA:UniProtKB.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007072; P:positive regulation of transcription on exit from mitosis; IMP:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0009303; P:rRNA transcription; IMP:UniProtKB.
102Q8Y3U2    229   NPD_LISMO NAD-dependent protein deacetylase O...2280.00000004     56.6     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
103Q4QB33    320   SIR4_LEIMA NAD-dependent protein deacetylase ...2570.00000004     57.8     23     39
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
104E9GD30    274   SIR5_DAPPU NAD-dependent protein deacylase OS...2560.00000004     57.4     25     45
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
105Q97VX5    247   NPD_SULSO NAD-dependent protein deacetylase O...1350.00000004     57     33     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106O67919    239   NPD_AQUAE NAD-dependent protein deacylase OS=...2220.00000005     56.6     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
107Q0P595    400   SIR7_BOVIN NAD-dependent protein deacetylase ...2940.00000006     57.8     21     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005731; C:nucleolus organizer region; ISS:UniProtKB.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007072; P:positive regulation of transcription on exit from mitosis; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0009303; P:rRNA transcription; ISS:UniProtKB.
108Q927A7    229   NPD_LISIN NAD-dependent protein deacetylase O...2280.00000009     55.8     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
109Q88BY5    262   NPD_PSEPK NAD-dependent protein deacylase OS=...2550.0000001     55.8     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
110Q7ZVK3    379   SIR2_DANRE NAD-dependent protein deacetylase ...2310.0000001     56.6     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
111Q88ZA0    234   NPD_LACPL NAD-dependent protein deacetylase O...2330.0000001     55.5     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
112F4P804    305   SIR4_BATDJ NAD-dependent protein deacetylase ...2860.0000002     55.8     20     36
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
113Q6N6U0    253   NPD_RHOPA NAD-dependent protein deacetylase O...1700.0000002     55.1     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
114Q5WKC8    237   NPD_BACSK NAD-dependent protein deacetylase O...2320.0000002     55.1     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
115Q6DHI5    305   SIR5_DANRE NAD-dependent protein deacylase si...2540.0000003     55.1     25     42GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
116Q8BKJ9    402   SIR7_MOUSE NAD-dependent protein deacetylase ...2920.0000003     55.5     22     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005731; C:nucleolus organizer region; ISS:UniProtKB.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007072; P:positive regulation of transcription on exit from mitosis; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0009303; P:rRNA transcription; ISS:UniProtKB.
117Q5HZN8    309   SIR5A_XENLA NAD-dependent protein deacylase s...2510.0000003     55.1     26     41GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
118Q89EA6    273   NPD2_BRAJA NAD-dependent protein deacetylase ...2440.0000004     54.3     22     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
119A8NWP2    299   SIR5_COPC7 NAD-dependent protein deacylase OS...2950.0000007     53.9     23     42
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
120Q8R216    333   SIR4_MOUSE NAD-dependent protein deacetylase ...2540.0000007     53.9     24     44GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.
121Q839C6    237   NPD_ENTFA NAD-dependent protein deacetylase O...2320.000001     52.8     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
records
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