Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR189W
Length:
666
Number of sequences:
5887
Description:
YDR189W SLY1 SGDID:S000002597, Chr IV from 838392-840392, Genome Release 64-1-1, Verified ORF, "Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P22213    666   SLY1_YEAST Protein SLY1 OS=Saccharomyces cere...6660     1355     100     100GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0030134; C:ER to Golgi transport vesicle; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.
GO:0019905; F:syntaxin binding; IDA:SGD.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0035543; P:positive regulation of SNARE complex assembly; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0046578; P:regulation of Ras protein signal transduction; IMP:UniProtKB.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.::GO:0048280; P:vesicle fusion with Golgi apparatus; IMP:SGD.
2O74534    639   SLY1_SCHPO Protein sly1 OS=Schizosaccharomyce...6533e-146     446     39     60GO:0005829; C:cytosol; IDA:PomBase.
GO:0000149; F:SNARE binding; ISS:PomBase.
GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0006904; P:vesicle docking involved in exocytosis; ISS:PomBase.
3Q851W1    623   SLY1_ORYSJ SEC1 family transport protein SLY1...6607e-115     364     34     54
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
4Q8WVM8    642   SCFD1_HUMAN Sec1 family domain-containing pro...6592e-113     361     32     54GO:0005801; C:cis-Golgi network; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005798; C:Golgi-associated vesicle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0019905; F:syntaxin binding; ISS:UniProtKB.
GO:0006892; P:post-Golgi vesicle-mediated transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; ISS:UniProtKB.::GO:0009636; P:response to toxin; IEP:UniProtKB.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; ISS:UniProtKB.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
5Q9SL48    627   SLY1_ARATH SEC1 family transport protein SLY1...6591e-111     356     34     53GO:0005829; C:cytosol; IDA:TAIR.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
6Q8BRF7    639   SCFD1_MOUSE Sec1 family domain-containing pro...6652e-111     355     31     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
7Q62991    637   SCFD1_RAT Sec1 family domain-containing prote...6722e-110     353     31     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005798; C:Golgi-associated vesicle; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0019905; F:syntaxin binding; IDA:RGD.
GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:RGD.::GO:0006892; P:post-Golgi vesicle-mediated transport; IDA:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IMP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:UniProtKB.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
8O18637    656   SLY1_DROVI Protein sly1 homolog OS=Drosophila...6794e-102     332     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
9Q24179    657   SLY1_DROME Protein sly1 homolog OS=Drosophila...6875e-102     332     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0000902; P:cell morphogenesis; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.::GO:0048190; P:wing disc dorsal/ventral pattern formation; IGI:FlyBase.
10Q54IJ1    673   SCFD1_DICDI Sec1 family domain-containing pro...6811e-78     270     31     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
11Q8SS97    521   SLY1_ENCCU SEC1 family transport protein SLY1...6011e-56     206     25     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
12Q54QC8    598   SEC1_DICDI Protein transport protein sec1 OS=...6712e-28     124     23     42
GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
13O00186    592   STXB3_HUMAN Syntaxin-binding protein 3 OS=Hom...6403e-27     120     23     43GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0031091; C:platelet alpha granule; IDA:UniProtKB.::GO:0042581; C:specific granule; IDA:UniProtKB.::GO:0070820; C:tertiary granule; IDA:UniProtKB.
GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IMP:UniProtKB.::GO:0043312; P:neutrophil degranulation; IEP:UniProtKB.::GO:0070527; P:platelet aggregation; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
14Q15833    593   STXB2_HUMAN Syntaxin-binding protein 2 OS=Hom...6228e-27     119     23     41GO:0042582; C:azurophil granule; IDA:UniProtKB.::GO:0044194; C:cytolytic granule; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0042581; C:specific granule; IDA:UniProtKB.::GO:0070820; C:tertiary granule; IDA:UniProtKB.
GO:0030348; F:syntaxin-3 binding; IPI:UniProtKB.
GO:0001909; P:leukocyte mediated cytotoxicity; IMP:UniProtKB.::GO:0043312; P:neutrophil degranulation; IEP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
15Q9C5P7    673   SEC1A_ARATH Protein transport Sec1a OS=Arabid...4181e-26     119     23     46
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
16Q60770    592   STXB3_MOUSE Syntaxin-binding protein 3 OS=Mus...6529e-26     115     23     42GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.
GO:0019905; F:syntaxin binding; IPI:UniProtKB.
GO:0007420; P:brain development; IMP:MGI.::GO:0015758; P:glucose transport; IDA:MGI.::GO:0030073; P:insulin secretion; IMP:MGI.::GO:0022615; P:protein to membrane docking; IMP:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032868; P:response to insulin stimulus; IMP:MGI.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
17Q64324    593   STXB2_MOUSE Syntaxin-binding protein 2 OS=Mus...3781e-25     115     26     45GO:0016324; C:apical plasma membrane; IDA:MGI.
GO:0017075; F:syntaxin-1 binding; IPI:MGI.::GO:0030348; F:syntaxin-3 binding; IPI:MGI.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
18Q28288    593   STXB2_CANFA Syntaxin-binding protein 2 OS=Can...3762e-25     115     25     45GO:0042582; C:azurophil granule; ISS:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0042581; C:specific granule; ISS:UniProtKB.::GO:0070820; C:tertiary granule; ISS:UniProtKB.
GO:0030348; F:syntaxin-3 binding; ISS:UniProtKB.
GO:0043312; P:neutrophil degranulation; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
19Q9C5X3    666   KEULE_ARATH SNARE-interacting protein KEULE O...3842e-25     115     25     46GO:0005829; C:cytosol; IDA:TAIR.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
20Q62753    594   STXB2_RAT Syntaxin-binding protein 2 OS=Rattu...3787e-25     113     25     45GO:0005737; C:cytoplasm; IDA:RGD.::GO:0030027; C:lamellipodium; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0017075; F:syntaxin-1 binding; IPI:RGD.::GO:0030348; F:syntaxin-3 binding; IPI:RGD.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0043304; P:regulation of mast cell degranulation; IMP:RGD.::GO:0010447; P:response to acidity; IEP:RGD.::GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
21Q5VNU3    659   SEC1B_ORYSJ Probable protein transport Sec1b ...4561e-23     109     23     45
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
22Q7XWP3    665   SEC1A_ORYSJ Probable protein transport Sec1a ...3845e-23     107     24     46
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
23Q6R748    594   STXB1_CHICK Syntaxin-binding protein 1 OS=Gal...6336e-23     107     21     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
24Q9SZ77    662   SEC1B_ARATH Protein transport Sec1b OS=Arabid...4236e-22     104     25     47GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
25Q54GE3    563   VPS45_DICDI Vacuolar protein sorting-associat...6436e-22     103     21     44GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; ISS:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0051082; F:unfolded protein binding; ISS:dictyBase.
GO:0006896; P:Golgi to vacuole transport; ISS:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
26O08700    570   VPS45_RAT Vacuolar protein sorting-associated...3742e-21     102     24     47GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0000299; C:integral to membrane of membrane fraction; IDA:BHF-UCL.
GO:0005515; F:protein binding; IPI:BHF-UCL.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
27P61765    594   STXB1_RAT Syntaxin-binding protein 1 OS=Rattu...6333e-21     102     20     43GO:0005829; C:cytosol; TAS:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0042802; F:identical protein binding; IPI:BHF-UCL.::GO:0019904; F:protein domain specific binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0017075; F:syntaxin-1 binding; IDA:MGI.
GO:0050821; P:protein stabilization; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0010807; P:regulation of synaptic vesicle priming; IMP:RGD.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
28Q5R6D2    594   STXB1_PONAB Syntaxin-binding protein 1 OS=Pon...6333e-21     102     20     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
29O08599    594   STXB1_MOUSE Syntaxin-binding protein 1 OS=Mus...6333e-21     102     20     43GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0017075; F:syntaxin-1 binding; IPI:MGI.
GO:0007412; P:axon target recognition; IMP:MGI.::GO:0060292; P:long term synaptic depression; IMP:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0032229; P:negative regulation of synaptic transmission, GABAergic; IDA:MGI.::GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.::GO:0007269; P:neurotransmitter secretion; IMP:MGI.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016188; P:synaptic vesicle maturation; IMP:MGI.::GO:0006904; P:vesicle docking involved in exocytosis; IMP:MGI.
30P61764    594   STXB1_HUMAN Syntaxin-binding protein 1 OS=Hom...6333e-21     102     20     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0031091; C:platelet alpha granule; IDA:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.
GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0017075; F:syntaxin-1 binding; ISS:UniProtKB.
GO:0007412; P:axon target recognition; ISS:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0014047; P:glutamate secretion; TAS:Reactome.::GO:0032229; P:negative regulation of synaptic transmission, GABAergic; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; TAS:Reactome.::GO:0070527; P:platelet aggregation; IMP:UniProtKB.::GO:0002576; P:platelet degranulation; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0010807; P:regulation of synaptic vesicle priming; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016188; P:synaptic vesicle maturation; ISS:UniProtKB.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
31P61763    594   STXB1_BOVIN Syntaxin-binding protein 1 OS=Bos...6333e-21     102     20     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:AgBase.
GO:0007412; P:axon target recognition; ISS:AgBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016188; P:synaptic vesicle maturation; ISS:AgBase.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
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