Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR189W
Length:
666
Number of sequences:
5887
Description:
YDR189W SLY1 SGDID:S000002597, Chr IV from 838392-840392, Genome Release 64-1-1, Verified ORF, "Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P61763    594   STXB1_BOVIN Syntaxin-binding protein 1 OS=Bos...6333e-21     102     20     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:AgBase.
GO:0007412; P:axon target recognition; ISS:AgBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016188; P:synaptic vesicle maturation; ISS:AgBase.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
32P97390    570   VPS45_MOUSE Vacuolar protein sorting-associat...3743e-21     101     23     47GO:0010008; C:endosome membrane; IDA:MGI.::GO:0000139; C:Golgi membrane; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
33Q9NRW7    570   VPS45_HUMAN Vacuolar protein sorting-associat...3892e-19     96.3     22     45GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0000299; C:integral to membrane of membrane fraction; ISS:BHF-UCL.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
34P34815    673   UNC18_CAEEL Putative acetylcholine regulator ...6267e-19     94.7     21     41GO:0030424; C:axon; IDA:WormBase.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0001956; P:positive regulation of neurotransmitter secretion; IMP:WormBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0007271; P:synaptic transmission, cholinergic; IMP:WormBase.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IMP:WormBase.
35P38932    577   VPS45_YEAST Vacuolar protein sorting-associat...3732e-18     92.4     26     45GO:0005829; C:cytosol; IDA:SGD.::GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0031201; C:SNARE complex; IPI:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0051082; F:unfolded protein binding; IMP:SGD.
GO:0032258; P:CVT pathway; IMP:SGD.::GO:0006895; P:Golgi to endosome transport; IGI:SGD.::GO:0006896; P:Golgi to vacuole transport; IMP:SGD.::GO:0048210; P:Golgi vesicle fusion to target membrane; IMP:SGD.::GO:0035543; P:positive regulation of SNARE complex assembly; IMP:SGD.::GO:0007035; P:vacuolar acidification; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
36Q07327    597   ROP_DROME Protein ROP OS=Drosophila melanogas...6385e-18     91.7     22     40GO:0005829; C:cytosol; IDA:FlyBase.::GO:0016020; C:membrane; TAS:FlyBase.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:FlyBase.::GO:0043195; C:terminal button; IDA:FlyBase.
GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007317; P:regulation of pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0009416; P:response to light stimulus; IMP:FlyBase.::GO:0016082; P:synaptic vesicle priming; NAS:FlyBase.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
37O94590    693   SEC1_SCHPO Protein transport protein sec1 OS=...6281e-17     90.9     23     42GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000149; F:SNARE binding; ISS:PomBase.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; ISS:PomBase.::GO:0006906; P:vesicle fusion; ISS:PomBase.
38O49048    569   VPS45_ARATH Vacuolar protein sorting-associat...4240.00000000000001     80.5     22     43GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.::GO:0005802; C:trans-Golgi network; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006886; P:intracellular protein transport; IGI:TAIR.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
39Q09805    558   YAB3_SCHPO Putative vacuolar protein sorting-...2440.0000000000002     77     23     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0006895; P:Golgi to endosome transport; IMP:PomBase.::GO:0006896; P:Golgi to vacuole transport; IMP:PomBase.::GO:0006900; P:membrane budding; NAS:PomBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
40Q29268    118   STXB2_PIG Syntaxin-binding protein 2 OS=Sus s...910.00000000005     65.1     34     59
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
41P30619    724   SEC1_YEAST Protein transport protein SEC1 OS=...6520.0000008     55.8     22     38GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0000149; F:SNARE binding; IDA:SGD.
GO:0031340; P:positive regulation of vesicle fusion; IDA:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IPI:SGD.
42Q96AX1    596   VP33A_HUMAN Vacuolar protein sorting-associat...3280.000008     52.8     24     43GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032418; P:lysosome localization; IDA:UniProtKB.::GO:0032400; P:melanosome localization; IDA:UniProtKB.::GO:0030220; P:platelet formation; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0048070; P:regulation of developmental pigmentation; ISS:UniProtKB.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
43Q63615    597   VP33A_RAT Vacuolar protein sorting-associated...3290.0005     47     25     42GO:0031410; C:cytoplasmic vesicle; IDA:RGD.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
44Q9D2N9    598   VP33A_MOUSE Vacuolar protein sorting-associat...3300.002     45.1     24     43GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0043473; P:pigmentation; IMP:MGI.::GO:0030220; P:platelet formation; IMP:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0048070; P:regulation of developmental pigmentation; IMP:MGI.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
45P34260    603   VP33A_CAEEL Vacuolar protein sorting-associat...3620.048     40.4     22     44
GO:0005515; F:protein binding; IPI:IntAct.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
46Q9Y1I2    617   VP33A_DROME Vacuolar protein sorting-associat...4590.62     37     20     38GO:0005829; C:cytosol; TAS:FlyBase.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000046; P:autophagic vacuole fusion; IMP:FlyBase.::GO:0048072; P:compound eye pigmentation; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0007032; P:endosome organization; IMP:FlyBase.::GO:0008333; P:endosome to lysosome transport; IMP:FlyBase.::GO:0008057; P:eye pigment granule organization; IMP:UniProtKB.::GO:0006727; P:ommochrome biosynthetic process; IMP:FlyBase.::GO:0006622; P:protein targeting to lysosome; IMP:UniProtKB.::GO:0031396; P:regulation of protein ubiquitination; IMP:FlyBase.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
47P27302    663   TKT1_ECOLI Transketolase 1 OS=Escherichia col...2221     36.2     22     36
GO:0030145; F:manganese ion binding; IDA:EcoCyc.::GO:0042803; F:protein homodimerization activity; IDA:EcoCyc.::GO:0030976; F:thiamine pyrophosphate binding; IDA:EcoCyc.::GO:0004802; F:transketolase activity; IDA:EcoliWiki.
GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IMP:EcoCyc.
48A0AIA3    204   LEXA_LISW6 LexA repressor OS=SLCC5334). GN=le...1395.6     33.1     24     44
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49Q39610    4499   DYHA_CHLRE Dynein alpha chain, flagellar oute...886.2     33.9     28     47GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0035086; C:flagellar axoneme; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007018; P:microtubule-based movement; IEA:InterPro.
50Q23972    999   SMG_DROME Protein Smaug OS=Drosophila melanog...1936.4     33.9     28     42GO:0000932; C:cytoplasmic mRNA processing body; IDA:FlyBase.
GO:0003730; F:mRNA 3'-UTR binding; TAS:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0000900; F:translation repressor activity, nucleic acid binding; TAS:FlyBase.
GO:0051236; P:establishment of RNA localization; IMP:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IMP:FlyBase.::GO:0043488; P:regulation of mRNA stability; IMP:FlyBase.
records
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