UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR180W

Length:

1493

Number of sequences:

5887

Description:

YDR180W SCC2 SGDID:S000002588, Chr IV from 821295-825776, Genome Release 64-1-1, Verified ORF, "Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; evolutionarily-conserved adherin"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q04002	1493	SCC2_YEAST Sister chromatid cohesion protein ...	1493	0	3033	100	100	GO:0005729; C:2-micrometer circle DNA; IDA:SGD.::GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0032116; C:SMC loading complex; IPI:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0030543; P:2-micrometer plasmid partitioning; IC:SGD.::GO:0006302; P:double-strand break repair; IMP:SGD.::GO:0034087; P:establishment of mitotic sister chromatid cohesion; IMP:SGD.::GO:0071169; P:establishment of protein localization to chromatin; IMP:SGD.::GO:0070550; P:rDNA condensation; IMP:SGD.::GO:0000972; P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; IMP:SGD.::GO:0070058; P:tRNA gene clustering; IMP:SGD.
2	Q750S2	1479	SCC2_ASHGO Sister chromatid cohesion protein ...	1491	0	1010	39	61	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
3	Q09725	1587	MIS4_SCHPO Sister chromatid cohesion protein ...	1202	6e-39	162	23	42	GO:0000794; C:condensed nuclear chromosome; IC:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0030892; C:mitotic cohesin complex; IDA:PomBase.::GO:0032116; C:SMC loading complex; IMP:PomBase.
									GO:0005515; F:protein binding; IPI:PomBase.
									GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:PomBase.::GO:0071921; P:cohesin localization to chromatin; IMP:PomBase.::GO:0007064; P:mitotic sister chromatid cohesion; IMP:PomBase.::GO:0007052; P:mitotic spindle organization; IMP:PomBase.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; IMP:PomBase.::GO:0000084; P:S phase of mitotic cell cycle; IMP:PomBase.
4	Q00333	2072	NPBL_COPC7 Protein rad9 OS=9003) (Inky cap fu...	1020	1e-35	152	25	42	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
5	Q95XZ5	2203	NPBL_CAEEL Nipped-B-like protein pqn-85 OS=Ca...	63	0.63	38.5	33	52	GO:0032116; C:SMC loading complex; ISS:UniProtKB.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0034088; P:maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0071688; P:striated muscle myosin thick filament assembly; IMP:WormBase.
6	Q6KCD5	2798	NIPBL_MOUSE Nipped-B-like protein OS=Mus musc...	618	0.00000000001	73.6	22	41	GO:0032116; C:SMC loading complex; ISS:UniProtKB.
									GO:0048703; P:embryonic viscerocranium morphogenesis; IMP:MGI.::GO:0045444; P:fat cell differentiation; IMP:MGI.::GO:0034088; P:maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:MGI.::GO:0045778; P:positive regulation of ossification; IMP:MGI.
7	Q6KC79	2804	NIPBL_HUMAN Nipped-B-like protein OS=Homo sap...	618	0.00000000003	72.4	22	41	GO:0032116; C:SMC loading complex; IDA:UniProtKB.
									GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
									GO:0007420; P:brain development; IMP:BHF-UCL.::GO:0034613; P:cellular protein localization; IMP:UniProtKB.::GO:0071481; P:cellular response to X-ray; IMP:UniProtKB.::GO:0050890; P:cognition; IMP:BHF-UCL.::GO:0048589; P:developmental growth; IMP:BHF-UCL.::GO:0042471; P:ear morphogenesis; IMP:BHF-UCL.::GO:0035117; P:embryonic arm morphogenesis; IMP:BHF-UCL.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:BHF-UCL.::GO:0035261; P:external genitalia morphogenesis; IMP:BHF-UCL.::GO:0048592; P:eye morphogenesis; IMP:BHF-UCL.::GO:0060325; P:face morphogenesis; IMP:BHF-UCL.::GO:0061010; P:gall bladder development; IMP:BHF-UCL.::GO:0034088; P:maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.::GO:0001656; P:metanephros development; NAS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0003151; P:outflow tract morphogenesis; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IDA:BHF-UCL.::GO:0048638; P:regulation of developmental growth; IMP:BHF-UCL.::GO:0045995; P:regulation of embryonic development; IMP:BHF-UCL.::GO:0042634; P:regulation of hair cycle; IMP:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:BHF-UCL.::GO:0061038; P:uterus morphogenesis; IMP:BHF-UCL.
8	Q7PLI2	2077	NIPB_DROME Nipped-B protein OS=Drosophila mel...	170	0.11	40.8	22	46	GO:0005654; C:nucleoplasm; IDA:FlyBase.::GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0032116; C:SMC loading complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; IDA:FlyBase.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0034088; P:maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0070193; P:synaptonemal complex organization; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0071733; P:transcriptional activation by promoter-enhancer looping; IGI:FlyBase.
9	A2AIV2	1811	VIR_MOUSE Protein virilizer homolog OS=Mus mu...	93	2.5	36.6	26	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
10	Q9KA55	346	CHEB_BACHD Chemotaxis response regulator prot...	108	3.9	35.4	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008984; F:protein-glutamate methylesterase activity; IEA:EC.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
									GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
11	Q5AK64	450	GATA_CANAL Glutamyl-tRNA(Gln) amidotransferas...	124	4.5	35.4	26	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.
									GO:0006412; P:translation; IEA:UniProtKB-KW.
12	C4YRY0	450	GATA_CANAW Glutamyl-tRNA(Gln) amidotransferas...	124	4.5	35.4	26	44	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.
									GO:0006412; P:translation; IEA:UniProtKB-KW.
13	Q92HD6	1892	Y835_RICCN UPF0192 protein RC0835 OS=Ricketts...	150	7.6	35	27	46	GO:0005727; C:extrachromosomal circular DNA; IEA:InterPro.
									GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
14	Q1ZXN4	524	C519C_DICDI Probable cytochrome P450 519C1 OS...	97	9.6	34.3	33	51	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.

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