Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR177W
Length:
215
Number of sequences:
5887
Description:
YDR177W UBC1 SGDID:S000002584, Chr IV from 816878-817525, Genome Release 64-1-1, Verified ORF, "Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q8S919    148   UBC5B_ORYSJ Ubiquitin-conjugating enzyme E2 5...1461e-40     141     47     65
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
32Q9C9Y7    149   UBC12_ARATH Probable ubiquitin-conjugating en...1461e-40     141     47     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
33P52486    199   UBCD4_DROME Ubiquitin-conjugating enzyme E2-2...1503e-40     142     52     69
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
34Q06AA9    147   UB2D2_PIG Ubiquitin-conjugating enzyme E2 D2 ...1456e-40     139     45     66
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
35P61078    147   UB2D3_RAT Ubiquitin-conjugating enzyme E2 D3 ...1456e-40     139     45     66GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
36Q5R4V7    147   UB2D3_PONAB Ubiquitin-conjugating enzyme E2 D...1456e-40     139     45     66GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
37P61079    147   UB2D3_MOUSE Ubiquitin-conjugating enzyme E2 D...1456e-40     139     45     66GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
38Q4R5N4    147   UB2D3_MACFA Ubiquitin-conjugating enzyme E2 D...1456e-40     139     45     66GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
39P61077    147   UB2D3_HUMAN Ubiquitin-conjugating enzyme E2 D...1456e-40     139     45     66GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
40P15731    148   UBC4_YEAST Ubiquitin-conjugating enzyme E2 4 ...1499e-40     139     45     63GO:0000502; C:proteasome complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.
GO:0006513; P:protein monoubiquitination; IDA:SGD.::GO:0000209; P:protein polyubiquitination; IMP:UniProtKB.::GO:0006950; P:response to stress; IDA:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
41Q3ZCF7    147   UB2D3_BOVIN Ubiquitin-conjugating enzyme E2 D...1457e-39     137     44     66GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
42O74196    147   UBC1_COLGL Ubiquitin-conjugating enzyme E2-16...1451e-38     136     45     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
43P46595    147   UBC4_SCHPO Ubiquitin-conjugating enzyme E2 4 ...1451e-38     136     44     63GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0008054; P:cyclin catabolic process; IGI:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
44Q9UVR2    147   UBC1_MAGO7 Ubiquitin-conjugating enzyme E2-16...1452e-38     135     45     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
45Q9FZ48    153   UBC36_ARATH Ubiquitin-conjugating enzyme E2 3...1465e-38     135     45     66GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0031372; C:UBC13-MMS2 complex; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0010039; P:response to iron ion; IMP:TAIR.::GO:0010053; P:root epidermal cell differentiation; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
46Q9SLE4    148   UBC29_ARATH Ubiquitin-conjugating enzyme E2 2...1466e-38     134     45     64
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
47P43102    147   UBC4_CANAX Ubiquitin-conjugating enzyme E2 4 ...1456e-38     134     44     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
48Q94490    148   UBCB_DICDI Ubiquitin conjugating enzyme E2 B ...1491e-37     134     40     64
GO:0004842; F:ubiquitin-protein ligase activity; ISS:dictyBase.
GO:0009653; P:anatomical structure morphogenesis; IMP:dictyBase.
49Q94A97    153   UBC35_ARATH Ubiquitin-conjugating enzyme E2 3...1461e-37     134     45     65GO:0031372; C:UBC13-MMS2 complex; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006301; P:postreplication repair; IGI:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0010039; P:response to iron ion; IMP:TAIR.::GO:0010053; P:root epidermal cell differentiation; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
50Q9FKT3    148   UBC30_ARATH Ubiquitin-conjugating enzyme E2 3...1461e-37     134     45     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
51P52485    232   UBCD2_DROME Ubiquitin-conjugating enzyme E2-2...1496e-37     134     44     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:FlyBase.
GO:0019915; P:lipid storage; IDA:FlyBase.
52P52483    207   UB2E3_MOUSE Ubiquitin-conjugating enzyme E2 E...1473e-36     132     44     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
53Q969T4    207   UB2E3_HUMAN Ubiquitin-conjugating enzyme E2 E...1473e-36     132     44     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
54Q2T9X7    207   UB2E3_BOVIN Ubiquitin-conjugating enzyme E2 E...1473e-36     132     44     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
55P51965    193   UB2E1_HUMAN Ubiquitin-conjugating enzyme E2 E...1494e-36     131     43     62GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042296; F:ISG15 ligase activity; IDA:HGNC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
56P52482    193   UB2E1_MOUSE Ubiquitin-conjugating enzyme E2 E...1494e-36     131     43     62GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
57Q91W82    201   UB2E2_MOUSE Ubiquitin-conjugating enzyme E2 E...1491e-35     130     42     62
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
58Q96LR5    201   UB2E2_HUMAN Ubiquitin-conjugating enzyme E2 E...1491e-35     130     42     62GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042296; F:ISG15 ligase activity; IDA:HGNC.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
59P52490    153   UBC13_YEAST Ubiquitin-conjugating enzyme E2 1...1505e-35     127     41     65GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0031371; C:ubiquitin conjugating enzyme complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0010994; P:free ubiquitin chain polymerization; IDA:SGD.::GO:0006301; P:postreplication repair; IMP:SGD.::GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; IDA:SGD.
60Q4R4I1    152   UBE2N_MACFA Ubiquitin-conjugating enzyme E2 N...1452e-34     125     42     63GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
61Q9EQX9    152   UBE2N_RAT Ubiquitin-conjugating enzyme E2 N O...1453e-34     125     42     63GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:RGD.
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